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Aminolevulinate, delta-, Synthase 1 (ALAS2) ELISA Kits

ALAS2 encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. Additionally we are shipping ALAS2 Antibodies (43) and ALAS2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ALAS2 100420897  
ALAS2 65155 P13195
ALAS2 11655 Q8VC19
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Top ALAS2 ELISA Kits at

Showing 3 out of 16 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.36 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 16 to 21 Days

More ELISA Kits for ALAS2 Interaction Partners

Human Aminolevulinate, delta-, Synthase 1 (ALAS2) interaction partners

  1. ALAS1 mRNA and activity were elevated approximately ~3- and 5-fold, and HMB synthase activity was approximately half-normal (~42%)

  2. These results indicate that ALAS1 is a novel NR5A-target gene and participates in steroid hormone production.

  3. Lon (show LONP1 ELISA Kits) peptidase 1 (show CNDP2 ELISA Kits) (LONP1 (show LONP1 ELISA Kits))-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells.

  4. REVIEW: mechanisms involving ALAS deficiency, point mutations, post translational processing, and complex formation with succinyl CoA (show OXCT1 ELISA Kits) synthetase subunit B in the pathogenesis of hereditary sideroblastic anemia.

  5. ALAS expression is regulated by AP-1 (show FOSB ELISA Kits) complex through sequestration of cAMP-response element protein (CRE)-binding protein (CBP (show CREBBP ELISA Kits)) coactivator in human cells

  6. ALAS gene expression is regulated by Hepatic nuclear factor 3 and nuclear factor 1

  7. First described frameshift ALAS2 mutation, CD506-507 (-C).

  8. in the liver of Acute liver failure patients, there may be an increase in free heme concentration which down-regulating ALAS1 gene expression

  9. Alternative splicing of human ALAS1 generates two mRNAs with different 5'-UTRs: a major one, where exon 1B is omitted, and a minor form containing exon 1B.

  10. 5-aminolevulinate synthase gene repression by the potent tumor promoter, TPA (show PLAT ELISA Kits), involves multiple signal transduction pathways

Mouse (Murine) Aminolevulinate, delta-, Synthase 1 (ALAS2) interaction partners

  1. RNAi-mediated silencing of hepatic Alas1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice.

  2. Both ALAS1 mRNA and protein content were induced in diabetic animals, accompanied by decreased Akt (show AKT1 ELISA Kits) phosphorylation and increased nuclear FOXO1 (show FOXO1 ELISA Kits), PGC-1alpha (show PPARGC1A ELISA Kits) and FOXO1 (show FOXO1 ELISA Kits)-PGC-1alpha (show PPARGC1A ELISA Kits) complex levels.

  3. Egr-1 (show EGR1 ELISA Kits) regulates the transcriptional repression of mouse delta-aminolevulinic acid synthase 1 by heme

  4. Mice bearing a homozygous knock-in allele were lethal by embryonic day 8.5, demonstrating that ALAS-N is essential for early embryogenesis.

  5. Ser (show SIGLEC1 ELISA Kits)-254 is critical for formation of a competent catalytic complex by coupling succinyl-CoA (show OXCT1 ELISA Kits) binding to enzyme conformational equilibria

  6. identified a drug-responsive enhancer in the ALAS1 gene

  7. Histidine-282 impacts a variety of ALAS functions, including substrate and pyridoxal 5'-phosphate (PLP (show C3 ELISA Kits))-binding and catalysis.

  8. The findings show that a B2 SINE retrotransposon can contribute to the regulation of ALAS1 and SINEs in 5'-UTR (show UTS2R ELISA Kits) regions contribute to inter-individual differences in gene expression.

ALAS2 Antigen Profile

Antigen Summary

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme\; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with ALAS2

  • aminolevulinate, delta-, synthase 1 (ALAS1) antibody
  • aminolevulinate, delta-, synthase 1 (alas1) antibody
  • alanyl-tRNA synthetase domain-containing protein (alaS1) antibody
  • alanyl-tRNA synthetase protein (alaS1) antibody
  • aminolevulinate, delta-, synthase 1 pseudogene (ALAS1) antibody
  • aminolevulinate, delta-, synthase 1 pseudogene (LOC100420897) antibody
  • aminolevulinate, delta-, synthase 1 (Alas1) antibody
  • aminolevulinate, delta-, synthetase 1 (alas1) antibody
  • aminolevulinic acid synthase 1 (Alas1) antibody
  • ALAS antibody
  • Alas-1 antibody
  • Alas-h antibody
  • ALAS-N antibody
  • ALAS1 antibody
  • ALAS3 antibody
  • ALASH antibody
  • ALASN antibody
  • MIG4 antibody
  • wu:fb58d01 antibody
  • wu:fi12g09 antibody

Protein level used designations for ALAS2

aminolevulinate, delta, synthase 1 , 5-aminolevulinate synthase, nonspecific, mitochondrial , aminolevulinate, delta-, synthase 1 , 5-aminolevulinic acid synthase 1 , Delta-ALA synthetase , delta-ALA synthase 1 , delta-aminolevulinate synthase 1 , 5-aminolevulinate synthase 1 , 5-aminolevulinate synthase, nonspecific, mitochondrial-like , alanyl-tRNA synthetase domain-containing protein , alanyl-tRNA synthetase protein , 5-aminolevulinic acid synthase , ALAS-H , migration-inducing protein 4 , delta-ALA synthetase 1 , ALA-S , ALAS-N , aminolevulinic acid synthase 1 , delta-ALA synthetase , ALA-synthase , aminolevulinate synthase 1 , aminolevulinate synthase H , succinyl-CoA: glycine C-succinyl transferase

460416 Pan troglodytes
493434 Xenopus (Silurana) tropicalis
698093 Macaca mulatta
100031030 Monodelphis domestica
100060491 Equus caballus
100172808 Pongo abelii
100231674 Taeniopygia guttata
100345847 Oryctolagus cuniculus
100388038 Callithrix jacchus
100473179 Ailuropoda melanoleuca
100607410 Nomascus leucogenys
5821016 Bordetella petrii DSM 12804
6399949 Rhizobium etli CIAT 652
100307125 Sus scrofa
100420897 Homo sapiens
444480 Xenopus laevis
211 Homo sapiens
476600 Canis lupus familiaris
534286 Bos taurus
65155 Rattus norvegicus
552895 Gallus gallus
101112853 Ovis aries
64608 Danio rerio
11655 Mus musculus
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