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The protein encoded by AMN is a type I transmembrane protein. Additionally we are shipping AMN Kits (12) and AMN Proteins (8) and many more products for this protein.
Showing 4 out of 5 products:
Human Polyclonal AMN Primary Antibody for ICC, IF - ABIN4280385
Galamb, Sipos, Spisák, Galamb, Krenács, Valcz, Tulassay, Molnár et al.: Potential biomarkers of colorectal adenoma-dysplasia-carcinoma progression: mRNA expression profiling and in situ protein detection on TMAs reveal 15 sequentially upregulated and 2 downregulated ... in Cellular oncology : the official journal of the International Society for Cellular Oncology 2008
heterozygous mutations in AMN (show ABCD1 Antibodies) in a family from the United Kingdom with clinical features of Imerslund-Grasbeck Syndrome
Our genetic screening of 154 families of patients with inherited cobalamin malabsorption revealed population-specific mutations, mutational hotspots, and functionally distinct regions in the three causal genes: CUBN (show CUBN Antibodies), AMN (show ABCD1 Antibodies), and GIF (show GIF Antibodies).
amnionless is essential for the correct luminal expression of cubilin (show CUBN Antibodies) in humans.
homozygous mutations affecting exons 1-4 of human AMN (show ABCD1 Antibodies) lead to megaloblastic anemia 1
cubilin (show CUBN Antibodies) and amnionless are subunits of a novel cubilin (show CUBN Antibodies)/amnionless (cubam) complex
Recurrent spontaneous abortions may be caused by mutations in the Amnionless gene.
This review summarizes recent data on the biological function of amnionless and focuses on its implication in embryonic nutrition and central nervous system malformations.
AMN (show TRAF3 Antibodies) may participate in meiosis in early spermatocytes and in functional differentiation of adult Leydig cells through the mediation of vitamin B(12) transport in the mouse testes
Amn (show TRAF3 Antibodies) is an essential component of the Cubn (show CUBN Antibodies) receptor complex
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.
, protein amnionless
, visceral endoderm-specific type 1 transmembrane protein
, type I transmembrane protein