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Amyloid P Component, serum (APCS) ELISA Kits

The protein encoded by APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. Additionally we are shipping Amyloid P Component, serum Antibodies (114) and Amyloid P Component, serum Proteins (32) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
APCS 325 P02743
APCS 29339 P23680
APCS 20219 P12246
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Top Amyloid P Component, serum ELISA Kits at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 50pg/mL 1.56-100 ng/mL Rat SAP/PTX2 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Mouse 50pg/mL 1.56-100 ng/mL Mouse SAP/PTX2 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Human
  96 Tests Log in to see 2 to 3 Days
$352.00
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Rabbit
  96 Tests Log in to see 11 to 13 Days
$785.71
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Guinea Pig
  96 Tests Log in to see 11 to 13 Days
$801.43
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Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
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Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
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Goat
  96 Tests Log in to see 11 to 13 Days
$801.43
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Top referenced Amyloid P Component, serum ELISA Kits

  1. Human APCS ELISA Kit for Sandwich ELISA - ABIN612669 : Jenny, Arnold, Kuller, Tracy, Psaty: Serum amyloid P and cardiovascular disease in older men and women: results from the Cardiovascular Health Study. in Arteriosclerosis, thrombosis, and vascular biology 2007 (PubMed)
    Show all 3 references for ABIN612669

  2. Rat (Rattus) APCS ELISA Kit for Sandwich ELISA - ABIN1889378 : Emsley, White, OHara, Oliva, Srinivasan, Tickle, Blundell, Pepys, Wood: Structure of pentameric human serum amyloid P component. in Nature 1994 (PubMed)

More ELISA Kits for Amyloid P Component, serum Interaction Partners

Human Amyloid P Component, serum (APCS) interaction partners

  1. Data suggest that serum amyloid P (SAP) activates CD209 DC-SIGN (show CD209 ELISA Kits) to regulate the innate immune system differently from C-reactive protein (CRP (show CRP ELISA Kits)), and that DC-SIGN (show CD209 ELISA Kits) is a target for antifibrotics.

  2. Here, it is reported that X-ray analysis of the SAP complex with CPHPC and cadmium ions provides higher resolution detail of the interaction than is observed with calcium ions.

  3. Compared to wildtype C57BL/6 mice, we find that in Apcs-/- "SAP knock-out" mice, bleomycin induces a more persistent inflammatory response and increased fibrosis.

  4. The effects of SAP and Xiapex (Collagenase Clostridium histolyticum) on fibrocytes derived from Dupuytren's disease, was evaluated.

  5. plasma protein serum amyloid P binds to FcgammaRI (show FCGR1A ELISA Kits) on monocytes to inhibit fibrocyte differentiation, and binds to FcgammaRIIa on neutrophils to reduce neutrophil adhesion.

  6. In the late phase post-myocardial infarct there is a coordinated decrease in immune response-inflammation proteins, except for SAP which showed an increase related to the specific activation of the classical complement pathway.

  7. 9 different proteins (haptoglobin (show HP ELISA Kits), transthyretin (show TTR ELISA Kits), apolipoprotein A-1 (show APOA1 ELISA Kits), serum amyloid P component, apolipoprotein E (show APOE ELISA Kits), complement factor H (show CFH ELISA Kits), fibrinogen gamma, thrombin (show F2 ELISA Kits), complement C3 (show C3 ELISA Kits)) were identified as a potential diagnostic pattern of Parkinson's disease.

  8. Human SAP binds phosphoethanolamine, while rabbits seem to have low levels of SAP that bind to a lesser extent.

  9. These results indicate that SAP functions as a host defense factor, similar to other peptidoglycan recognition proteins and nucleotide-binding oligomerization domain-like receptors.

  10. SAP may act as an effective receptor mimic to limit influenza A virus infection of airway epithelial cells.

Mouse (Murine) Amyloid P Component, serum (APCS) interaction partners

  1. SAP deficiency mitigated foam cell formation and atherosclerotic development in apoE (show APOE ELISA Kits)(-/-) mice, due to reduction in macrophages recruitment, polarization and pro-inflammatory cytokines

  2. Data suggest that serum amyloid P (SAP) activates CD209 DC-SIGN (show CD209 ELISA Kits) to regulate the innate immune system differently from C-reactive protein (CRP (show CRP ELISA Kits)), and that DC-SIGN (show CD209 ELISA Kits) is a target for antifibrotics.

  3. observations suggest that serum amyloid P, at least in part, uses FcgammaRI (show FCGR1A ELISA Kits) and FcRgamma (show FCER1G ELISA Kits) to inhibit fibrocyte differentiation

  4. Bglu3 is confirmed to be a locus affecting diabetes susceptibility, and Apcs is a probable candidate gene.

  5. binding of SAP to ALD (show ABCD1 ELISA Kits)-DNA could switch macrophage phenotypic polarization from proinflammatory M2b to anti-inflammatory M2a via PI3K/Akt (show AKT1 ELISA Kits)-ERK (show EPHB2 ELISA Kits) signaling activation, thus exerting protective and therapeutic interventions on murine lupus nephritis

  6. SAP has an effect on macrophages in fibrotic lung disease

  7. sFRP4 (show SFRP4 ELISA Kits) negatively regulates bone formation without disrupting phosphorus homeostasis.

  8. Binding of mouse and human SAP to immobilized influenza virus was compared. Mouse SAP bound much less avidly than human SAP.mouse SAP apparently plays no significant role during infection of mice with influenza virus.

  9. Targeted pharmacological depletion of serum amyloid P component for treatment of amyloidosis

  10. during murine tuberculosis (TB) SAP levels were increased; purified mouse SAP inhibited the intra-alveolar macrophage M. tuberculosis growth, in vitro; SAP may thus contribute both to the pathogenesis and pulmonary innate immunity in TB

Amyloid P Component, serum (APCS) Antigen Profile

Antigen Summary

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Gene names and symbols associated with APCS

  • amyloid P component, serum (APCS) antibody
  • amyloid P component, serum (Apcs) antibody
  • C-reactive protein, pentraxin-related (CRP) antibody
  • serum amyloid P-component (Apcs) antibody
  • serum amyloid P-component-like (LOC100352593) antibody
  • APCS antibody
  • PTX2 antibody
  • Sap antibody

Protein level used designations for APCS

amyloid P component, serum , pentraxin , C-reactive protein , amyloid P component serum , 9.5S alpha-1-glycoprotein , pentaxin-related , serum amyloid P-component , serum amyloid P component , Serum amyloid P-component , SAP , APCS amyloid P-component serum protein

GENE ID SPECIES
457427 Pan troglodytes
100126558 Meleagris gallopavo
325 Homo sapiens
396921 Sus scrofa
29339 Rattus norvegicus
100726823 Cavia porcellus
514488 Bos taurus
776376 Gallus gallus
20219 Mus musculus
100352593 Oryctolagus cuniculus
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