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Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein Proteins (APBB1IP)

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein Antibodies (65) and Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APBB1IP 54518 Q7Z5R6
Rat APBB1IP APBB1IP 307171  
APBB1IP 54519 Q8R5A3
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Top Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

APBB1IP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) Interaction Partners

Human Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) interaction partners

  1. Disruption of the RIAM/lamellipodin-integrin-talin complex markedly impairs cell migration.

  2. RIAM is a critical component of the phagocytosis machinery downstream of Rap1 and mediates its function by recruiting talin to the phagocytic complement receptors.

  3. integrin-triggered, RIAM-dependent MEK (show MAP2K1 Proteins) activation represents a key feedback event required for efficient focal adhesion disassembly.

  4. RIAM was recruited to the lymphocyte plasma membrane through its Ras association and pleckstrin (show PLEK Proteins) homology domains, both of which were required for lymphocyte adhesion.

  5. RIAM might contribute to the dissemination of melanoma cells.

  6. by regulating the localization of PLC-gamma1, RIAM plays a central role in TCR signaling and the transcription of target genes.

  7. all-trans-retinoic acid-inducible RARP1 selectively affects signal transduction and may contribute to myeloid and megakaryocytic differentiation.(RARP1)

  8. Data pinpoint PREL1 as the first direct link between Ras signalling and cytoskeletal remodelling via Ena/VASP (show VASP Proteins) proteins during cell migration and spreading.

  9. a minimized 50-residue Rap (show LRPAP1 Proteins)-RIAM module containing the talin binding site of RIAM joined to the membrane-targeting sequence of Rap1A (show RAP1A Proteins). This minimized Rap (show LRPAP1 Proteins)-RIAM module was sufficient to target talin to the plasma membrane and to mediate integrin activation

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) interaction partners

  1. we show that leukocyte integrin activation critically depends on RIAM both in vitro and in vivo

  2. These in vivo results confirm a role for RIAM in the regulation of some, but not all, leukocyte integrins and suggest that RIAM-regulated integrin activation is required for trafficking of lymphocytes

  3. Conformational activation of talin by PREL-1 triggers integrin-mediated cell adhesion.

  4. crystal structure of an active, GTP (show AK3 Proteins)-bound GTPase (show RACGAP1 Proteins) domain of Rap1 (show TERF2IP Proteins) in complex with the Ras association (RA)-pleckstrin (show PLEK Proteins) homology (PH) structural module of RIAM at 1.65 A, is reported.

  5. generated RIAM-null mice and found that they are viable, fertile, and apparently healthy

  6. As talin engages F-actin, force exerted on the R2R3 helical bundles disrupts RIAM binding and exposes the vinculin (show VCL Proteins) binding sites, which recruit vinculin (show VCL Proteins) to stabilize the complex.

  7. Data demonstrate a novel mechanism by which alphavbeta3 integrin acts to locally suppress beta1 integrin activation and regulate VASP (show VASP Proteins) and RIAM to control cell adhesion and migration.

Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) Protein Profile

Protein Summary

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling.

Gene names and symbols associated with APBB1IP

  • amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (apbb1ip)
  • amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (APBB1IP)
  • amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (LOC100228743)
  • amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (Apbb1ip)
  • 9930118P07Rik protein
  • APBB1IP protein
  • INAG1 protein
  • MGC80693 protein
  • PREL1 protein
  • Prp48 protein
  • RARP1 protein
  • RIAM protein
  • zgc:63968 protein

Protein level used designations for APBB1IP

amyloid beta A4 precursor protein-binding family B member 1-interacting protein , APBB1-interacting protein 1 , Amyloid beta A4 precursor protein-binding family B member 1-interacting protein , amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein , amyloid beta A4 precursor protein-binding family B member 1-interacting protein-like , PREL-1 , RARP-1 , Rap1-GTP-interacting adaptor molecule , Rap1-interacting adaptor molecule , proline rich EVH1 ligand 1 , proline-rich EVH1 ligand 1 , proline-rich protein 73 , rap1-GTP-interacting adapter molecule , retinoic acid-responsive proline-rich protein 1 , proline-rich protein 48

GENE ID SPECIES
393607 Danio rerio
446995 Xenopus laevis
450361 Pan troglodytes
477985 Canis lupus familiaris
533670 Bos taurus
707383 Macaca mulatta
100125005 Xenopus (Silurana) tropicalis
100228743 Taeniopygia guttata
100439620 Pongo abelii
100065539 Equus caballus
100598478 Nomascus leucogenys
54518 Homo sapiens
307171 Rattus norvegicus
420492 Gallus gallus
54519 Mus musculus
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