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anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) Antibodies

The protein encoded by APBB2 interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Kits (4) and Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APBB2 323 Q92870
APBB2 11787 Q9DBR4
APBB2 305338  
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Top anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-APBB2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using APBB2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using APBB2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-APBB2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959274 concentration 10 ug/ml. Anti-APBB2 antibody IHC staining of human adrenal cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959274 concentration 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB APBB2 Antibody (Center) (ABIN1881063) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the APBB2 antibody detected the APBB2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with APBB2 antibody ABIN214621 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

APBB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Antibodies

  1. Cow (Bovine) Polyclonal APBB2 Primary Antibody for WB - ABIN2786292 : Hong, Hsu, Schultz, Pratt, Mattison, Chang: Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response. in BMC molecular biology 2007 (PubMed)

More Antibodies against Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Interaction Partners

Human Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) interaction partners

  1. APBB2 was differentially expressed between Fibromyalgia patients and healthy controls.

  2. results provide additional evidence of a genetic interaction between GSK3beta (show GSK3b Antibodies) and APBB2 and further suggest that GSK3beta (show GSK3b Antibodies) is involved in the pathophysiology of both of the primary neuropathologies of Alzheimer's disease

  3. The APBB2 rs13133980 G allele was over-represented in centenarians with severe cognitive impairment compared to individuals without this disability.

  4. FE65L1 potentiates gamma-secretase processing of APP (show APP Antibodies) CTFs. This requires binding of FE65L1 to APP (show APP Antibodies) and APP (show APP Antibodies) CTFs. Enhanced APP (show APP Antibodies) CTF (show NFIA Antibodies) processing can be detected in early endosome vesicles

  5. rs13133980 associated significantly with age of onset in Alzheimer disease. Genetic variations in APBB2 may affect late onset AD susceptibility.

  6. the apoptosis inhibitory domain of FE65 (show APBB1 Antibodies)-like protein 1 regulates both apoptotic and caspase (show CASP3 Antibodies)-independent programmed cell death mediated by TNF (show TNF Antibodies)

  7. In response to TNF (show TNF Antibodies), Zfra is upregulated and modulates TNF (show TNF Antibodies)-mediated cell death via interacting with TRADD (show TRADD Antibodies), FADD (show FADD Antibodies) and RIP (show HRB Antibodies) (death-inducing signaling complex) at the receptor level, and downstream effectors NF-kappaB (show NFKB1 Antibodies), p53 (show TP53 Antibodies), WOX1 (show WWOX Antibodies), and JNK1 (show MAPK8 Antibodies).

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) interaction partners

  1. Findings show that amyloid precursor protein (show APP Antibodies)-binding proteins FE65 (show APBB1 Antibodies) and FE65L1 are essential for the maintenance of lens transparency.

  2. FE65 (show APBB1 Antibodies) proteins contribute to physiological APP (show APP Antibodies) processing and accumulation of amyloid precursor protein (show APP Antibodies) metabolic products resulting from NMDA receptor activation

  3. While mitogen activated protein kinase 8 (JNK1 (show MAPK8 Antibodies)) is a downstream effector of the Tumor Necrosis Factor (TNF (show TNF Antibodies)) signaling, Zfra regulation of the TNF (show TNF Antibodies) cytotoxic function is likely due to its interaction, in part, with JNK1 (show MAPK8 Antibodies).

  4. the apoptosis inhibitory domain of FE65 (show APBB1 Antibodies)-like protein 1 regulates both apoptotic and caspase (show CASP3 Antibodies)-independent programmed cell death mediated by TNF (show TNF Antibodies)

  5. Targeted deletion of two members of the FE65 (show APBB1 Antibodies) family of adaptor proteins, FE65 (show APBB1 Antibodies) and FE65L1, results in cortical dysplasia and suggests that FE65 (show APBB1 Antibodies) proteins are involved in basement membrane assembly.

  6. Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein (show APP Antibodies) reveals a novel peptide binding mode

Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) Antigen Profile

Protein Summary

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with APBB2

  • amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) (APBB2) antibody
  • amyloid beta (A4) precursor protein-binding, family B, member 2 (APBB2) antibody
  • amyloid beta (A4) precursor protein-binding, family B, member 2 (apbb2) antibody
  • amyloid beta (A4) precursor protein-binding, family B, member 2 (Apbb2) antibody
  • 2310007D03Rik antibody
  • APBB2 antibody
  • DKFZp469I236 antibody
  • DKFZp469L0910 antibody
  • FE65L antibody
  • FE65L1 antibody
  • RGD1562438 antibody
  • Rirl1 antibody
  • TR2L antibody
  • Zfra antibody

Protein level used designations for APBB2

amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) , amyloid beta A4 precursor protein-binding, family B, member 2 , amyloid beta (A4) precursor protein-binding, family B, member 2 , amyloid beta A4 precursor protein-binding, family B, member 2-like , amyloid beta A4 precursor protein-binding family B member 2-like , Fe65-like 1 , amyloid beta A4 precursor protein-binding family B member 2 , protein Fe65-like 1 , zinc finger-like protein

GENE ID SPECIES
422781 Gallus gallus
461184 Pan troglodytes
701342 Macaca mulatta
100144693 Xenopus (Silurana) tropicalis
100171964 Pongo abelii
100174507 Pongo abelii
100353587 Oryctolagus cuniculus
100409701 Callithrix jacchus
100463683 Ailuropoda melanoleuca
323 Homo sapiens
488831 Canis lupus familiaris
514013 Bos taurus
11787 Mus musculus
305338 Rattus norvegicus
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