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Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) ELISA Kits

The protein encoded by APBB2 interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Antibodies (57) and Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
APBB2 323 Q92870
APBB2 11787 Q9DBR4
APBB2 305338  
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Top Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
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Rat
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$999.43
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Human
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$999.43
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Mouse
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$999.43
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More ELISA Kits for Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 Interaction Partners

Human Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) interaction partners

  1. APBB2 was differentially expressed between Fibromyalgia patients and healthy controls.

  2. results provide additional evidence of a genetic interaction between GSK3beta and APBB2 and further suggest that GSK3beta is involved in the pathophysiology of both of the primary neuropathologies of Alzheimer's disease

  3. The APBB2 rs13133980 G allele was over-represented in centenarians with severe cognitive impairment compared to individuals without this disability.

  4. FE65L1 potentiates gamma-secretase processing of APP (show APP ELISA Kits) CTFs. This requires binding of FE65L1 to APP (show APP ELISA Kits) and APP (show APP ELISA Kits) CTFs. Enhanced APP (show APP ELISA Kits) CTF (show NFIA ELISA Kits) processing can be detected in early endosome vesicles

  5. rs13133980 associated significantly with age of onset in Alzheimer disease. Genetic variations in APBB2 may affect late onset AD susceptibility.

  6. the apoptosis inhibitory domain of FE65 (show APBB1 ELISA Kits)-like protein 1 regulates both apoptotic and caspase (show CASP3 ELISA Kits)-independent programmed cell death mediated by TNF (show TNF ELISA Kits)

  7. In response to TNF (show TNF ELISA Kits), Zfra is upregulated and modulates TNF (show TNF ELISA Kits)-mediated cell death via interacting with TRADD (show TRADD ELISA Kits), FADD (show FADD ELISA Kits) and RIP (show HRB ELISA Kits) (death-inducing signaling complex) at the receptor level, and downstream effectors NF-kappaB (show NFKB1 ELISA Kits), p53 (show TP53 ELISA Kits), WOX1 (show WWOX ELISA Kits), and JNK1 (show MAPK8 ELISA Kits).

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) interaction partners

  1. Findings show that amyloid precursor protein (show APP ELISA Kits)-binding proteins FE65 (show APBB1 ELISA Kits) and FE65L1 are essential for the maintenance of lens transparency.

  2. FE65 (show APBB1 ELISA Kits) proteins contribute to physiological APP (show APP ELISA Kits) processing and accumulation of amyloid precursor protein (show APP ELISA Kits) metabolic products resulting from NMDA receptor activation

  3. While mitogen activated protein kinase 8 (JNK1 (show MAPK8 ELISA Kits)) is a downstream effector of the Tumor Necrosis Factor (TNF (show TNF ELISA Kits)) signaling, Zfra regulation of the TNF (show TNF ELISA Kits) cytotoxic function is likely due to its interaction, in part, with JNK1 (show MAPK8 ELISA Kits).

  4. the apoptosis inhibitory domain of FE65 (show APBB1 ELISA Kits)-like protein 1 regulates both apoptotic and caspase (show CASP3 ELISA Kits)-independent programmed cell death mediated by TNF (show TNF ELISA Kits)

  5. Targeted deletion of two members of the FE65 (show APBB1 ELISA Kits) family of adaptor proteins, FE65 (show APBB1 ELISA Kits) and FE65L1, results in cortical dysplasia and suggests that FE65 (show APBB1 ELISA Kits) proteins are involved in basement membrane assembly.

  6. Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein (show APP ELISA Kits) reveals a novel peptide binding mode

Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2) Antigen Profile

Antigen Summary

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with APBB2

  • amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) (APBB2) antibody
  • amyloid beta (A4) precursor protein-binding, family B, member 2 (APBB2) antibody
  • amyloid beta (A4) precursor protein-binding, family B, member 2 (apbb2) antibody
  • amyloid beta (A4) precursor protein-binding, family B, member 2 (Apbb2) antibody
  • 2310007D03Rik antibody
  • APBB2 antibody
  • DKFZp469I236 antibody
  • DKFZp469L0910 antibody
  • FE65L antibody
  • FE65L1 antibody
  • RGD1562438 antibody
  • Rirl1 antibody
  • TR2L antibody
  • Zfra antibody

Protein level used designations for APBB2

amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) , amyloid beta A4 precursor protein-binding, family B, member 2 , amyloid beta (A4) precursor protein-binding, family B, member 2 , amyloid beta A4 precursor protein-binding, family B, member 2-like , amyloid beta A4 precursor protein-binding family B member 2-like , Fe65-like 1 , amyloid beta A4 precursor protein-binding family B member 2 , protein Fe65-like 1 , zinc finger-like protein

GENE ID SPECIES
422781 Gallus gallus
461184 Pan troglodytes
701342 Macaca mulatta
100144693 Xenopus (Silurana) tropicalis
100171964 Pongo abelii
100174507 Pongo abelii
100353587 Oryctolagus cuniculus
100409701 Callithrix jacchus
100463683 Ailuropoda melanoleuca
323 Homo sapiens
488831 Canis lupus familiaris
514013 Bos taurus
11787 Mus musculus
305338 Rattus norvegicus
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