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Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 8 Proteins (ALS2CR8)

May be a transcription factor (By similarity).

list all proteins Gene Name GeneID UniProt
Mouse ALS2CR8 ALS2CR8 241066 Q8VHI4
Human ALS2CR8 ALS2CR8 79800 Q8N187
Rat ALS2CR8 ALS2CR8 301446  
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More Proteins for Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 8 (ALS2CR8) Interaction Partners

Mouse (Murine) Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 8 (ALS2CR8) interaction partners

  1. This report that loss of CaRF (show CDKN2AIP Proteins) leads to enhanced NMDAR (show GRIN1 Proteins)-dependent induction of both Bdnf (show BDNF Proteins) IV and the activity-regulated gene Arc (show NOL3 Proteins), and we investigate potential mechanisms as well as biological consequences of this change in transcriptional regulation.

  2. Carf (show CDKN2AIP Proteins)(+/-) and Carf (show CDKN2AIP Proteins)(-/-) mice were impaired in their ability to acquire timed response thresholds relative to Carf (show CDKN2AIP Proteins)(+/+) mice.

  3. These data strongly support the characterization of CaRF (show CDKN2AIP Proteins) as a unique transcription factor and provide the first insight into the program of CaRF (show CDKN2AIP Proteins)-regulated transcription in neurons.

  4. the data of this study reveal novel roles for CaRF (show CDKN2AIP Proteins) in the organization and/or function of neural circuits that underlie essential aspects of learning and memory.

  5. Cloned as a calcium- and neural-selective transcriptional activator of the gene for Brain-Derived Neurotrophic Factor (BDNF (show BDNF Proteins)).

Human Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 8 (ALS2CR8) interaction partners

  1. Cloned as a calcium- and neural-selective transcriptional activator of the gene for Brain-Derived Neurotrophic Factor (BDNF (show BDNF Proteins)).

Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 8 (ALS2CR8) Protein Profile

Protein Summary

May be a transcription factor (By similarity).

Gene names and symbols associated with ALS2CR8

  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 (ALS2CR8)
  • novel protein similar to human amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 (ALS2CR8) (CH211-195C14.1)
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 (CARF)
  • calcium response factor (Carf)
  • calcium responsive transcription factor (CARF)
  • calcium responsive transcription factor (Carf)
  • Als2cr8 protein
  • ECBRC-FC1 protein
  • ECBRC-FC2 protein
  • LOC555728 protein
  • NYD-SP24 protein

Protein level used designations for ALS2CR8

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 , novel protein similar to human amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 (ALS2CR8) , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog , calcium-responsive transcription factor , calcium-response factor CaRF , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein , calcium-response factor , testis development protein NYD-SP24 , calcium response factor

GENE ID SPECIES
424090 Gallus gallus
459889 Pan troglodytes
555728 Danio rerio
509072 Bos taurus
478877 Canis lupus familiaris
241066 Mus musculus
79800 Homo sapiens
301446 Rattus norvegicus
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