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ANAPC1 encodes a subunit of the anaphase-promoting complex. Additionally we are shipping Anaphase Promoting Complex Subunit 1 Kits (8) and and many more products for this protein.
Showing 10 out of 119 products:
Human Polyclonal ANAPC1 Primary Antibody for IHC, ELISA - ABIN1532106
Jörgensen, Gräslund, Betz, Ståhl, Larsson, Höög: Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex. in Gene 2001
Human Polyclonal ANAPC1 Primary Antibody for EIA, WB - ABIN499291
Peters: The anaphase promoting complex/cyclosome: a machine designed to destroy. in Nature reviews. Molecular cell biology 2006
findings suggest a tumor suppressor role for APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) in melanocytes and that targeting PAX3 (show PAX3 Antibodies) may be a strategy for treating melanoma.
Human Cytomegalovirus UL21a but not UL97 can disrupt APC (show APC Antibodies)/C function, leading to the accumulation of substrates and that UL21a is necessary and sufficient to induce the degradation of APC1 (show SLC25A24 Antibodies), in addition to the previously reported APC4 (show ANAPC4 Antibodies) and APC5 (show ANAPC5 Antibodies).
Data indicate that regulation of Rad17 (show RAD17 Antibodies) turnover is through the Cdh1 (show CDH1 Antibodies)/anaphase-promoting complex pathway in breast cancer cells.
EYA1 (show EYA1 Antibodies) is efficiently degraded during mitotic exit in a ANAPC1-dependent manner and these two proteins physically interact.
analysis of ubiquitylation of p53 (show TP53 Antibodies) by the APC (show APC Antibodies)/C inhibitor Trim39 (show TRIM39 Antibodies)
Single nucleotide polymorhpisms of ANAPC1 were associated with nicotine dependence.
Studies indicate that the APC (show APC Antibodies)/C is tightly regulated by its co-activators and by the spindle assembly checkpoint.
the ability of Emi1 (show FBXO5 Antibodies) to inhibit APC (show APC Antibodies)/C is negatively regulated by CDKs
Data demonstrate that PFKFB3 (show PFKFB3 Antibodies) is essential for cell division and that it is regulated by APC (show APC Antibodies)/C-Cdh1 (show CDH1 Antibodies) and SKP1 (show SKP1 Antibodies)-CUL1 (show CUL1 Antibodies)-F (SCF (show KITLG Antibodies))-beta-TrCP (show BTRC Antibodies).
These results suggest that APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) is involved in ubiquitination and down-regulating the stability of TRB3 (show TAS2R13 Antibodies) protein.
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.
anaphase promoting complex subunit 1
, adenomatous polyposis coli protein
, anaphase-promoting complex 1 (meiotic checkpoint regulator)
, anaphase-promoting complex subunit 1
, cyclosome subunit 1
, mitotic checkpoint regulator
, testis-specific gene 24 protein
, meiotic check point regulator