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ANAPC1 encodes a subunit of the anaphase-promoting complex. Additionally we are shipping Anaphase Promoting Complex Subunit 1 Antibodies (128) and and many more products for this protein.
findings suggest a tumor suppressor role for APC (show APC ELISA Kits)/C(Cdh1 (show CDH1 ELISA Kits)) in melanocytes and that targeting PAX3 (show PAX3 ELISA Kits) may be a strategy for treating melanoma.
Human Cytomegalovirus UL21a but not UL97 can disrupt APC (show APC ELISA Kits)/C function, leading to the accumulation of substrates and that UL21a is necessary and sufficient to induce the degradation of APC1 (show SLC25A24 ELISA Kits), in addition to the previously reported APC4 (show ANAPC4 ELISA Kits) and APC5 (show ANAPC5 ELISA Kits).
Data indicate that regulation of Rad17 (show RAD17 ELISA Kits) turnover is through the Cdh1 (show CDH1 ELISA Kits)/anaphase-promoting complex pathway in breast cancer cells.
EYA1 (show EYA1 ELISA Kits) is efficiently degraded during mitotic exit in a ANAPC1-dependent manner and these two proteins physically interact.
analysis of ubiquitylation of p53 (show TP53 ELISA Kits) by the APC (show APC ELISA Kits)/C inhibitor Trim39 (show TRIM39 ELISA Kits)
Single nucleotide polymorhpisms of ANAPC1 were associated with nicotine dependence.
Studies indicate that the APC (show APC ELISA Kits)/C is tightly regulated by its co-activators and by the spindle assembly checkpoint.
the ability of Emi1 (show FBXO5 ELISA Kits) to inhibit APC (show APC ELISA Kits)/C is negatively regulated by CDKs
Data demonstrate that PFKFB3 (show PFKFB3 ELISA Kits) is essential for cell division and that it is regulated by APC (show APC ELISA Kits)/C-Cdh1 (show CDH1 ELISA Kits) and SKP1 (show SKP1 ELISA Kits)-CUL1 (show CUL1 ELISA Kits)-F (SCF (show KITLG ELISA Kits))-beta-TrCP (show BTRC ELISA Kits).
These results suggest that APC (show APC ELISA Kits)/C(Cdh1 (show CDH1 ELISA Kits)) is involved in ubiquitination and down-regulating the stability of TRB3 (show TAS2R13 ELISA Kits) protein.
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.
anaphase promoting complex subunit 1
, adenomatous polyposis coli protein
, anaphase-promoting complex 1 (meiotic checkpoint regulator)
, anaphase-promoting complex subunit 1
, cyclosome subunit 1
, mitotic checkpoint regulator
, testis-specific gene 24 protein
, meiotic check point regulator