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anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) Antibodies

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Additionally we are shipping Anaphase Promoting Complex Subunit 11 Proteins (9) and Anaphase Promoting Complex Subunit 11 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANAPC11 498030  
ANAPC11 51529 Q9NYG5
ANAPC11 66156 Q9CPX9
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Top anti-Anaphase Promoting Complex Subunit 11 Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a, amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto- tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see references below. 0.1 mL Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-ANAPC11 / APC11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959612 concentration 5 ug/ml. Anti-ANAPC11 / APC11 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959612 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a 100 μL Log in to see 2 to 3 Days
$369.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ANAPC11 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IP, ELISA, WB   100 μL Log in to see 8 to 10 Days
$610.50
Details
Human Mouse Un-conjugated IF   100 μL Log in to see 8 to 10 Days
$493.17
Details

ANAPC11 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Anaphase Promoting Complex Subunit 11 Antibodies

  1. Human Polyclonal ANAPC11 Primary Antibody for EIA, IP - ABIN117941 : Chan, Lee, Chim, Kok, Waye, Lee, Fung, Tsui: Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p. in Journal of cellular biochemistry 2001 (PubMed)
    Show all 8 references for ABIN117941

  2. Human Polyclonal ANAPC11 Primary Antibody for EIA, WB - ABIN783600 : Peters: The anaphase promoting complex/cyclosome: a machine designed to destroy. in Nature reviews. Molecular cell biology 2006 (PubMed)

More Antibodies against Anaphase Promoting Complex Subunit 11 Interaction Partners

Human Anaphase Promoting Complex Subunit 11 (ANAPC11) interaction partners

  1. siRNA targeted against Apc11 could hamper entry into G2/M phase.

  2. The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2.

  3. Studies indicate that APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) is required to maintain genomic stability.

  4. APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

  5. Inhibition of APC11 function by H(2)O(2) contributes to the delay in cell cycle progression through mitosis that is characteristic of cells subjected to oxidative stress

Anaphase Promoting Complex Subunit 11 (ANAPC11) Antigen Profile

Protein Summary

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.

Gene names and symbols associated with ANAPC11

  • anaphase promoting complex subunit 11 (anapc11) antibody
  • anaphase promoting complex subunit 11 (Anapc11) antibody
  • anaphase-promoting complex subunit 11-like (LOC615066) antibody
  • Apc11p (APC11) antibody
  • anaphase-promoting complex subunit Apc11 (apc11) antibody
  • similar to S. cerevisiae APC11 (YDL008W) anaphase promoting complex subunit (APC11) antibody
  • ubiquitin-protein ligase Anaphase Promoting Complex (APC11) antibody
  • anaphase promoting complex subunit 11 (APC11) antibody
  • hypothetical protein (APC11) antibody
  • anaphase-promoting complex/cyclosome 11 (APC11) antibody
  • anaphase promoting complex subunit 11 (ANAPC11) antibody
  • anaphase promoting complex subunit 11 (LOC692923) antibody
  • APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11) antibody
  • anaphase-promoting complex subunit 11 (APC11) antibody
  • 1110011I19Rik antibody
  • anapc11 antibody
  • anaphase-promoting complex/cyclosome 11 antibody
  • APC11 antibody
  • Apc11p antibody
  • DDBDRAFT_0187183 antibody
  • DDBDRAFT_0231277 antibody
  • DDB_0187183 antibody
  • DDB_0231277 antibody
  • F10A16.17 antibody
  • F10A16_17 antibody
  • R75218 antibody
  • RGD1561880 antibody
  • si:dkey-237i9.4 antibody
  • zgc:153671 antibody

Protein level used designations for ANAPC11

anaphase promoting complex subunit 11 , anaphase promoting complex subunit 11 homolog , anaphase-promoting complex subunit 11 , anaphase promoting complex subunit 11-like , Apc11p , Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition , anaphase-promoting complex subunit Apc11 , potential anaphase-promoting complex subunit Apc11 , ubiquitin-protein ligase Anaphase Promoting Complex , hypothetical protein , anaphase-promoting complex/cyclosome 11 , APC11 anaphase promoting complex subunit 11 homolog , cyclosome subunit 11 , anaphase promoting complex subunit 11 (yeast APC11 homolog) , hepatocellular carcinoma-associated RING finger protein , APC11

GENE ID SPECIES
496247 Xenopus laevis
496610 Xenopus (Silurana) tropicalis
498030 Rattus norvegicus
615066 Bos taurus
851554 Saccharomyces cerevisiae S288c
2543187 Schizosaccharomyces pombe 972h-
3639005 Candida albicans SC5314
4852029 Scheffersomyces stipitis CBS 6054
5718640 Chlamydomonas reinhardtii
7203954 Phaeodactylum tricornutum CCAP 1055/1
8248072 Micromonas sp. RCC299
8625855 Dictyostelium discoideum AX4
9320604 Arabidopsis lyrata subsp. lyrata
454972 Pan troglodytes
483370 Canis lupus familiaris
692923 Bombyx mori
768140 Danio rerio
100173127 Pongo abelii
51529 Homo sapiens
66156 Mus musculus
616275 Bos taurus
819756 Arabidopsis thaliana
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