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The protein encoded by ANG is an exceedingly potent mediator of new blood vessel formation. Additionally we are shipping Angiogenin Antibodies (131) and Angiogenin Kits (78) and many more products for this protein.
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Human Angiogenin Protein expressed in Escherichia coli (E. coli) - ABIN1046530
Kurachi, Davie, Strydom, Riordan, Vallee: Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor. in Biochemistry 1986
Show all 2 references for ABIN1046530
Association analyses revealed the significant associations (P < 0.05) between the porcine ANG g. 149G>T polymorphism and mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean platelet volume (MPV) and platelet-large cell ratio (P-LCR).
ANG K17I variant is rare in Caucasian patients and controls and increases the risk for amyotrophic lateral sclerosis
ANG rs11701 variant is a genetic risk factor for Parkinson's disease in Taiwan population.Mutations in ANG are not a common cause for idiopathic Parkinson's disease.
In conclusion, angiogenin secretion by HCCs (show HCCS Proteins) favors tumor development by inducing HSC (show FUT1 Proteins) activation and ECM (show MMRN1 Proteins) remodeling.
the present study established a link between Ang and FHL3 (show FHL3 Proteins) proteins and identifies a new pathway for regulating astrocytoma progression.
Studied the mechanism of ligand binding in human angiogenin using the NMR chemical shift projection analysis.
ANG could play a pivotal role in the development of bladder cancer through regulating AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling pathway.
Suggest a novel regulatory pathway whereby breast tumor-derived angiogenin directly activates angiogenesis through inhibition of miR (show MLXIP Proteins)-542-3p.
a biological explanation for the loss-of-function of D22G-Angiogenin leading to ALS, and suggest that the L35P-Angiogenin mutation would probably cause ALS symptoms in individuals harboring this mutation
High angiogenin expression is associated with bladder cancer.
a novel mechanism of ANG in regulating PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling pathway via RI, is reported.
angiogenin and ILK (show ILK Proteins) signaling pathway plays a pivotal role in mediating the inhibitory effects of RI on melanoma cells growth
Our data provide new insights into the paracrine activities of angiogenin in the nervous system, and further highlight the critical role of non-neuronal cells in the pathogenesis of Amyotrophic lateral sclerosis
RNase 4 (show RNASE4 Proteins) and RNase 5/ang 1 (show ANGPT1 Proteins) are unique among the RNase A (show RNASE1 Proteins) ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing.
ANG plays an important role in neurite pathfinding and this has implications for amyotrophic lateral sclerosis.
Angiogenin mRNA was expressed in murine skin in a hair-cycle dependent manner, with maximum levels observed at the late anagen.
All three types of the ANG inhibitor suppress rRNA transcription of the prostate luminal epithelial cells and inhibit AKT (show AKT1 Proteins)-induced PIN (show DYNLL1 Proteins), indicating an essential role of ANG in AKT (show AKT1 Proteins)-mediated cell proliferation and survival.
Murine angiogenin mRNA and protein are upregulated in motoneurons in response to hypoxia, and that Hypoxia-Inducible Factor 1 (show HIF1A Proteins) is sufficient and required to upregulate angiogenin expression during hypoxia.
This study is the first to demonstrate that hypoxia upregulates Ang1 (show ANGPT1 Proteins) expression via HIF2alpha (show EPAS1 Proteins)-mediated transcriptional activation in pericytes, which plays a key role in angiogenesis.
rAAV-mediated angiogenin gene transfer induces angiogenesis and modifies left ventricular remodeling in rats with myocardial infafrction.
bovine angiogenin is the substance mainly responsible for the inhibitory effect of bovine milk on osteoclast-mediated bone resorption
The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
, epididymis luminal protein 168
, ribonuclease 5
, angiogenin, ribonuclease A family, member 1
, leukocyte ribonuclease A-1
, ribonuclease A
, ribonuclease A/angiogenin
, angiogenin ribonuclease 2