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The protein encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. Additionally we are shipping AMOTL1 Antibodies (34) and and many more products for this protein.
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AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin (show NF2 ELISA Kits).
phosphorylation-deficient S793Ala mutant of AMOTL1 showed a shorter half-life and conferred resistance to energy-stress-induced YAP (show YAP1 ELISA Kits) inhibition.
study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP (show CREBBP ELISA Kits), CBFA2T3 (show CBFA2T3 ELISA Kits), AMOTL1, FAT4, FBXO11 (show FBXO11 ELISA Kits), PLA2G4D (show PLA2G4D ELISA Kits), TRRAP (show TRRAP ELISA Kits) and USH2A (show USH2A ELISA Kits).
miR (show MLXIP ELISA Kits)-124 binds AmotL1 3'UTR (show UTS2R ELISA Kits) and down-regulates its expression repressing vasculogenic mimicry and cell motility in cervical cancer cells.
Scaffold proteins angiomotin (Amot (show AMOT ELISA Kits)) and angiomotin (show AMOT ELISA Kits)-related AmotL1 and AmotL2 (show AMOTL2 ELISA Kits) were recently identified as negative regulators of YAP (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits) by preventing their nuclear translocation.
These results suggested that IFN-gamma exhibits anti-angiogenesis effects by regulating the expression of TNF-alpha-induced AmotL1 via NFkappaB in emphysema lungs.
AmotL1 and ZO-2 (show TJP2 ELISA Kits) are two candidates that could be harnessed to control the oncogenic function of YAP (show YAP1 ELISA Kits).
By yeast two-hybrid screening, angiomotin-like 1 (AmotL1) was identified as a host factor that interacts with the M protein (show MYOM2 ELISA Kits) of parainfluenza virus 5 (PIV5).
The angiomotin-like 1 is involved in actin-cytoskeleton-based processes, in part, via its interaction with a p80-angiomotin-containing complex and the actin cytoskeleton
Amot (show AMOT ELISA Kits) and AmotL1 have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot (show AMOT ELISA Kits) appears to control the cell polarity and AmotL1 affects the stability of cell-cell junctions.
Amot (show AMOT ELISA Kits), Amotl1, and Amotl2 (show AMOTL2 ELISA Kits) are differentially expressed in uterine cells during the peri (show POSTN ELISA Kits)-implantation period.
Data show that MUPP1 (show MPDZ ELISA Kits) interacts with angiomotin (Amot (show AMOT ELISA Kits)), JEAP/Amot (show AMOT ELISA Kits)-like 1 and MASCOT/Amot (show AMOT ELISA Kits)-like 2, and that all the Amot (show AMOT ELISA Kits)/JEAP family proteins also interacted with Patj (show INADL ELISA Kits), a close relative of MUPP1 (show MPDZ ELISA Kits).
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
angiomotin like 1
, angiomotin-like protein 1-like
, angiomotin-like protein 1
, junction-enriched and associated protein
, junction-enriched and -associated protein