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Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Additionally we are shipping ANGPTL2 Antibodies (42) and ANGPTL2 Kits (35) and many more products for this protein.
Showing 10 out of 13 products:
ANGPTL2 and TGF-beta1 (show TGFB1 Proteins) positively regulate each other as renal fibrosis progresses.
signaling involving ANGPTL2 and LILRB2 (show LILRB2 Proteins) is important for lung cancer development
ANGPTL2 may be a useful marker for detecting early postoperative recurrence in patients with gastric cancer.
In lumbar spinal stenosis, Angptl2 promotes inflammation in ligamentum flavum(LF) tissue by activating IL-6 (show IL6 Proteins) expression, leading to LF degeneration and hypertrophy.
ANGPTL2 promotes adipose tissue macrophage and T lymphocyte accumulation and leads to insulin (show INS Proteins) resistance.
Serum ANGPTL2 in GC patients was significantly higher than for healthy controls.
Angptl2 induces proinflammatory responses in peritoneal macrophages and monocytes.
Serum ANGPTL2 concentration was associated with carotid atherosclerosis in patients with type 2 diabetes.
these findings are the first to suggest a considerable role for Angptl2 in the pathogenesis of unstable coronary disease in a clinical context
These results suggested that ANGPTL2 was a potential biomarker for gastric cancer.
Angptl2 might therefore represent a multistep regulator of CNV pathogenesis and serve as a new therapeutic target for age-related macular degeneration.
In angptl2 knockdown mice, ACh (show FGFR3 Proteins)-mediated endothelium-dependent vasodilation was greater than in WT mice. Lack of angptl2 expression limits the metabolic stress induced by a high-fat diet and maintains endothelial function in mice.
knockdown of angptl2 may be protective against ANG II (show AGT Proteins)-induced cerebral endothelial dysfunction; it favors the production of NO increasing endothelial cell resistance to stress.
Angptl2 expression was reduced in PHD3 (show EGLN3 Proteins)(-/-) bone-marrow-derived macrophages under stress conditions. PHD3 (show EGLN3 Proteins) affects the production of Angptl2 and additionally influences the response toward this apoptosis-modulating factor.
Angptl2-induced inflammation increases susceptibility to microenvironmental changes, allowing increased oxidative stress and decreased Msh2 (show MSH2 Proteins) expression.
Endothelial cell-derived Angptl2 accelerates vascular inflammation by activating proinflammatory signaling in endothelial cells and increasing macrophage infiltration, leading to endothelial dysfunction and atherosclerosis progression.
periodic expression of ANGPTL2 is regulated by a molecular clock
Our findings demonstrated Angptl2 to be upregulated in corneal inflammation, and highlight that corneal hemangiogenesis and lymphangiogenesis may be driven by Angptk2 overexpression via macrophage infiltration and IL-1beta (show IL1B Proteins) expression.
Data show that angiopoietin-like proteins zangptl1 and 2 are required for definitive HSPCs formation, and genetically interact with notch (show NOTCH1 Proteins) receptor.
developmental expression of Angptl1 (show ANGPTL1 Proteins), 2 and 6 in zebrafish
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.
, fibrinogen-like protein
, angiopoietin-related protein 2
, angiopoietin-related protein 2-like
, angiopoietin-like protein 2
, angiopoietin-like 2 a
, angiopoietin-related protein-2
, angiopoietin related protein 2