You are viewing an incomplete version of our website. Please click to reload the website as full version.

Angiopoietin-Like 3 Proteins (ANGPTL3)

ANGPTL3 encodes a member of a family of secreted proteins that function in angiogenesis. Additionally we are shipping ANGPTL3 Antibodies (162) and ANGPTL3 Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANGPTL3 27329 Q9Y5C1
ANGPTL3 30924 Q9R182
Rat ANGPTL3 ANGPTL3 502970  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ANGPTL3 Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Human DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
$299.25
Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
$225.75
Details
HOST_Human Mouse DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
$225.75
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$728.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$798.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$618.75
Details

ANGPTL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Mouse (Murine) ,
, , ,

Top referenced ANGPTL3 Proteins

  1. Human ANGPTL3 Protein expressed in Human - ABIN1344368 : Broxmeyer, Srour, Cooper, Wallace, Hangoc, Youn: Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors. in Blood cells, molecules & diseases 2012 (PubMed)

  2. Human ANGPTL3 Protein expressed in HEK-293 Cells - ABIN2180588 : Conklin, Gilbertson, Taft, Maurer, Whitmore, Smith, Walker, Chen, Wattler, Nehls, Lewis: Identification of a mammalian angiopoietin-related protein expressed specifically in liver. in Genomics 2000 (PubMed)

More Proteins for Angiopoietin-Like 3 (ANGPTL3) Interaction Partners

Zebrafish Angiopoietin-Like 3 (ANGPTL3) interaction partners

  1. Knockdown of Angptl3 decreases liver size in developing zebrafish.

Human Angiopoietin-Like 3 (ANGPTL3) interaction partners

  1. ANGPTL3 levels were associated with fasting insulin (show INS Proteins) and the homeostasis model assessment of insulin (show INS Proteins) resistance in Korean children.

  2. An ANGPTL3-4-8 model was proposed to explain the variations of lipoprotein lipase (LPL (show LPL Proteins)) activity during the fed-fast cycle. Feeding induces ANGPTL8, activating the ANGPTL8-ANGPTL3 pathway, which inhibits LPL (show LCP1 Proteins) in cardiac and skeletal muscles to direct circulating triglycerides (TG) to white adipose tissue; the reverse is true during fasting, which suppresses ANGPTL8 but induces ANGPTL4 (show ANGPTL4 Proteins), thereby directing TG to muscles.

  3. Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion

  4. Novel mutation Y344S found in ANGPTL3 gene in two diabetic patients with familial hypobetalipoproteinemia.

  5. Data suggest that silencing of ANGPTL 3 (angiopoietin-like protein 3) improves insulin (show INS Proteins) sensitivity.

  6. HCV core represses ANGPTL-3 expression through loss of HNF-1alpha binding activity and blockage of LXR/RXR transactivation

  7. Data suggest that genetic polymorphisms in ANGPTL3 (angiopoietin-like 3 protein), TIMD4 (show TIMD4 Proteins) (T cell immunoglobulin mucin-4 (show MUC4 Proteins)), and apolipoproteins A5 and B are among the genetic determinants of hypertriglyceridemia in Amerindian populations. [REVIEW]

  8. ANGPTL3 is positively associated with low-density lipoprotein cholesterol and high-density lipoprotein cholesterol and not with metabolic syndrome traits including triglycerides.

  9. Identification of loss-of-function ANGPTL3 mutation is shedding light on a possible role of ANGPTL3 at the crossroads of lipoproteins, fatty acids, and glucose metabolism. [Review]

  10. Although partial Angptl3 deficiency did not affect the activities of lipolytic enzymes, the complete absence of Angptl3 results in an increased lipoprotein lipase (show LPL Proteins) activity and mass and low circulating free fatty acid levels.

Mouse (Murine) Angiopoietin-Like 3 (ANGPTL3) interaction partners

  1. This model suggests a general mechanism by which TAG trafficking is coordinated by lipasin, Angptl3 and Angptl4 (show ANGPTL4 Proteins) at different nutritional statuses.

  2. Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion

  3. The deletion of ANGPTL3 tremendously attenuates proteinuria and protects podocytes from injury in a mouse model of adriamycin-induced nephropathy.

  4. ANGPTL3 has a role in regulating white adipose tissue energy homeostasis but not in liver

  5. Data indicate that expression of Angptl3 in hematopoietic stem cell (HSC (show FUT1 Proteins)) through lentiviral transduction promoted HSC (show FUT1 Proteins) expansion.

  6. Angptl3 could induce actin filament rearrangement, mainly in lamellipodia formation, and that this process was mediated by integrin alpha(V)beta-mediated FAK and PI3K phosphorylation and Rac1 activation.

  7. Furin (show FURIN Proteins) has a role as the primary in vivo convertase of ANGPTL3 and endothelial lipase (show LIPG Proteins) in hepatocytes

  8. ANGPTL8, a paralog of ANGPTL3 that arose through duplication of an ancestral DOCK gene, regulates postprandial TAG and fatty acid metabolism by controlling activation of its progenitor, and perhaps other ANGPTLs

  9. Angptl3, as an extrinsic factor, thus supports the stemness of hematopoietic stem cells in the bone marrow niche.

  10. ANGPTL3 expression is upregulated in puromycin-induced podocyte damage and is associated with the reduction of perlecan (show HSPG2 Proteins) and agrin (show AGRN Proteins) expression

Pig (Porcine) Angiopoietin-Like 3 (ANGPTL3) interaction partners

  1. First report of molecular cloning and characterization of ANGPTL3 in pigs, which will be helpful for a better understanding of the role of ANGPTLs in lipid metabolism.

ANGPTL3 Protein Profile

Protein Summary

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.

Gene names and symbols associated with Angiopoietin-Like 3 Proteins (ANGPTL3)

  • angiopoietin-like 3 (angptl3)
  • angiopoietin-like 3 (ANGPTL3)
  • angiopoietin-like 3 (LOC100230785)
  • angiopoietin-like 3 (Angptl3)
  • ANG-5 protein
  • ANGPT5 protein
  • ANGPTL3 protein
  • ANL3 protein
  • fb60e11 protein
  • fb66h02 protein
  • FHBL2 protein
  • hypl protein
  • LOC100230785 protein
  • wu:fb60e11 protein
  • wu:fb66h02 protein
  • zgc:111943 protein

Protein level used designations for Angiopoietin-Like 3 Proteins (ANGPTL3)

angiopoietin-like 3 , WITHDRAWN: zgc:111943 , angiopoietin-related protein 3-like , angiopoietin 5 , angiopoietin-related protein 3 , angiopoietin-like protein 3 , hypolipidemia

GENE ID SPECIES
114421 Danio rerio
479547 Canis lupus familiaris
695499 Macaca mulatta
742370 Pan troglodytes
100230785 Taeniopygia guttata
100412498 Callithrix jacchus
100442706 Pongo abelii
100473620 Ailuropoda melanoleuca
100616799 Monodelphis domestica
27329 Homo sapiens
30924 Mus musculus
502970 Rattus norvegicus
782603 Bos taurus
445466 Sus scrofa
100189558 Gallus gallus
Selected quality suppliers for ANGPTL3 Proteins (ANGPTL3)
Did you look for something else?