Angiopoietin-Like 2 Proteins (ANGPTL2)

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Additionally we are shipping ANGPTL2 Antibodies (71) and ANGPTL2 Kits (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANGPTL2 23452 Q9UKU9
ANGPTL2 26360 Q9R045
ANGPTL2 171100  
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Top ANGPTL2 Proteins at antibodies-online.com

Showing 9 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$778.00
Details
Human Cells Mouse Fc Tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$688.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$608.00
Details
Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days
$976.25
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$797.50
Details
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$893.75
Details

ANGPTL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human
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Mouse (Murine) , ,
, ,
Rat (Rattus)

More Proteins for Angiopoietin-Like 2 (ANGPTL2) Interaction Partners

Human Angiopoietin-Like 2 (ANGPTL2) interaction partners

  1. Results reveal a novel cascade comprising sequential P. gingivalis lipopolysaccharide --> ANGPTL2 --> integrin alpha5beta1 --> inflammatory cytokine induction, which might be responsible for inducing potent periodontal disorganization activity in gingival epithelial cells. Via this pathway, ANGPTL2 functions in the pathogenesis of periodontitis and contributes to prolonging chronic inflammation in patients with systemi...

  2. In patients with type 2 diabetes, serum ANGPTL2 concentrations were independently associated with death and MACE.

  3. Elevated serum ANGPTL2 levels are a novel risk factor for the development of CVD in the general population. This association is partially mediated by metabolic disorders and inflammation.

  4. Increased ANGPTL2 expression contributes to proliferation and invasion of gastric cancer cells.

  5. Aberrant expression of ANGPTL2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.

  6. Reduced leukocyte DNA methylation (show HELLS Proteins) in the promoter region of ANGPTL2 is associated with the pro-inflammatory environment that characterizes patients with post-ACS (show PLA2G15 Proteins) differently from age-matched healthy controls. Methylation of different CpGs in ANGPTL2 gene may prove to be a reliable biomarker of coronary disease

  7. At 11-13 weeks in pregnancies that develop GDM, the serum concentration of ANGPTL2 is increased, and it can be combined with maternal factors to provide effective early screening for GDM.

  8. ANGPTL2 and TGF-beta1 (show TGFB1 Proteins) positively regulate each other as renal fibrosis progresses.

  9. signaling involving ANGPTL2 and LILRB2 (show LILRB2 Proteins) is important for lung cancer development

  10. ANGPTL2 may be a useful marker for detecting early postoperative recurrence in patients with gastric cancer.

Mouse (Murine) Angiopoietin-Like 2 (ANGPTL2) interaction partners

  1. These results support the importance of ANGPTL2 in the stem cell niche in regulating stemness and epithelial wound healing in the intestine.

  2. we provide the first evidence for ANGPTL2 function in the acute ischemic brain. Infiltrated macrophage-derived ANGPTL2 enhanced inflammatory responses and was associated with severe brain tissue damage in the acute phase of ischemic stroke.

  3. Angptl2 deficiency in lung epithelial cells and resident alveolar macrophages causes severe lung fibrosis seen following bleomycin treatment, suggesting that ANGPTL2 derived from these cell types plays a protective role against fibrosis in lung.

  4. Angptl2 regulates not only adipose tissue metabolism but also bone metabolism

  5. findings suggest that macrophage-derived ANGPTL2 promotes an innate immune response in those cells by enhancing proinflammatory activity and NO production required to fight infection.

  6. Angptl2 might therefore represent a multistep regulator of CNV pathogenesis and serve as a new therapeutic target for age-related macular degeneration.

  7. ANGPTL2 promotes adipose tissue macrophage and T lymphocyte accumulation and leads to insulin (show INS Proteins) resistance.

  8. Angptl2 induces proinflammatory responses in peritoneal macrophages and monocytes.

  9. In angptl2 knockdown mice, ACh (show FGFR3 Proteins)-mediated endothelium-dependent vasodilation was greater than in WT mice. Lack of angptl2 expression limits the metabolic stress induced by a high-fat diet and maintains endothelial function in mice.

  10. knockdown of angptl2 may be protective against ANG II (show AGT Proteins)-induced cerebral endothelial dysfunction; it favors the production of NO increasing endothelial cell resistance to stress.

Zebrafish Angiopoietin-Like 2 (ANGPTL2) interaction partners

  1. Data show that angiopoietin-like proteins zangptl1 and 2 are required for definitive HSPCs formation, and genetically interact with notch (show NOTCH1 Proteins) receptor.

  2. developmental expression of Angptl1 (show ANGPTL1 Proteins), 2 and 6 in zebrafish

ANGPTL2 Protein Profile

Protein Summary

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.

Gene names and symbols associated with Angiopoietin-Like 2 Proteins (ANGPTL2)

  • angiopoietin like 2 (ANGPTL2)
  • angiopoietin-like 2 (Angptl2)
  • angiopoietin-like 2b (angptl2b)
  • angiopoietin-like 2 (ANGPTL2)
  • angiopoietin like 2 (angptl2)
  • angiopoietin like 2 L homeolog (angptl2.L)
  • angiopoietin like 2 (Angptl2)
  • AI593246 protein
  • angptl2 protein
  • angptl2a protein
  • arp2 protein
  • AW260363 protein
  • fbnl protein
  • harp protein
  • wu:fc41g02 protein

Protein level used designations for Angiopoietin-Like 2 Proteins (ANGPTL2)

angiopoietin-like protein 2 , angiopoietin-related protein 2 , angiopoietin related protein 2 , angiopoietin-like 2 , angiopoietin-related protein-2 , fibrinogen-like protein , angiopoietin-like 2 a , angiopoietin-related protein 2-like

GENE ID SPECIES
23452 Homo sapiens
26360 Mus musculus
171100 Rattus norvegicus
464743 Pan troglodytes
480720 Canis lupus familiaris
503514 Danio rerio
512019 Bos taurus
701444 Macaca mulatta
776031 Gallus gallus
100038298 Xenopus (Silurana) tropicalis
100085245 Ornithorhynchus anatinus
100125230 Xenopus laevis
100126164 Sus scrofa
100354822 Oryctolagus cuniculus
100394668 Callithrix jacchus
100067146 Equus caballus
100728986 Cavia porcellus
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