Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
ANGPTL3 encodes a member of a family of secreted proteins that function in angiogenesis. Additionally we are shipping ANGPTL3 Kits (62) and ANGPTL3 Proteins (27) and many more products for this protein.
Showing 10 out of 161 products:
Human Polyclonal ANGPTL3 Primary Antibody for EIA, WB - ABIN452736
Shan, Yu, Liu, Hu, Sturgis, Miranda, Liu: The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms. in The Journal of biological chemistry 2009
Show all 2 references for 452736
Human Polyclonal ANGPTL3 Primary Antibody for WB - ABIN390666
Shimamura, Matsuda, Kobayashi, Ando, Ono, Koishi, Furukawa, Makishima, Shimomura: Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes. in Biochemical and biophysical research communications 2003
Show all 2 references for 390666
Cow (Bovine) Polyclonal ANGPTL3 Primary Antibody for WB - ABIN2775402
Kathiresan, Melander, Guiducci, Surti, Burtt, Rieder, Cooper, Roos, Voight, Havulinna, Wahlstrand, Hedner, Corella, Tai, Ordovas, Berglund, Vartiainen, Jousilahti, Hedblad, Taskinen, Newton-Cheh et al.: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ... in Nature genetics 2008
Human Monoclonal ANGPTL3 Primary Antibody for ELISA, WB - ABIN165378
Ono, Shimizugawa, Shimamura, Yoshida, Noji-Sakikawa, Ando, Koishi, Furukawa: Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo. in The Journal of biological chemistry 2003
Knockdown of Angptl3 decreases liver size in developing zebrafish.
participants with heterozygous loss-of-function variants in ANGPTL3 had significantly lower serum levels of triglycerides, HDL (show HSD11B1 Antibodies) cholesterol, and LDL cholesterol than participants without these variants.
ANGPTL3 deficiency is associated with protection from coronary artery disease.
our data shows that ANGPTL3, 4 and 8 are increased in obesity and type 2 diabetes (T2D). ANGPTL8 associates with ANGPTL3 in the non-diabetic subjects while it associated more with ANGPTL4 (show ANGPTL4 Antibodies) in the obese and T2D subjects.
ANGPTL3 is specifically correlated with HDL (show HSD11B1 Antibodies)-c, apoA-I (show APOA1 Antibodies), SAA (show SAA1 Antibodies) and HDL (show HSD11B1 Antibodies) function in female non-diabetic participants. The decrease of ANGPTL3 level in female T2DM patients might contribute to its weak association to HDL (show HSD11B1 Antibodies) components and function.
The ANGPTL3 gene lies within DOCK7 (show DOCK7 Antibodies), although the variant is within non-coding regions outside of ANGPTL3, within DOCK7 (show DOCK7 Antibodies), suggesting complex long-range regulatory effects on gene expression in coronary artery disease.
ANGPTL3 levels were associated with fasting insulin (show INS Antibodies) and the homeostasis model assessment of insulin (show INS Antibodies) resistance in Korean children.
An ANGPTL3-4-8 model was proposed to explain the variations of lipoprotein lipase (LPL (show LPL Antibodies)) activity during the fed-fast cycle. Feeding induces ANGPTL8, activating the ANGPTL8-ANGPTL3 pathway, which inhibits LPL (show LCP1 Antibodies) in cardiac and skeletal muscles to direct circulating triglycerides (TG) to white adipose tissue; the reverse is true during fasting, which suppresses ANGPTL8 but induces ANGPTL4 (show ANGPTL4 Antibodies), thereby directing TG to muscles.
Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion
Novel mutation Y344S found in ANGPTL3 gene in two diabetic patients with familial hypobetalipoproteinemia.
Data suggest that silencing of ANGPTL 3 (angiopoietin-like protein 3) improves insulin (show INS Antibodies) sensitivity.
This model suggests a general mechanism by which TAG trafficking is coordinated by lipasin, Angptl3 and Angptl4 (show ANGPTL4 Antibodies) at different nutritional statuses.
The deletion of ANGPTL3 tremendously attenuates proteinuria and protects podocytes from injury in a mouse model of adriamycin-induced nephropathy.
ANGPTL3 has a role in regulating white adipose tissue energy homeostasis but not in liver
Data indicate that expression of Angptl3 in hematopoietic stem cell (HSC (show FUT1 Antibodies)) through lentiviral transduction promoted HSC (show FUT1 Antibodies) expansion.
Angptl3 could induce actin filament rearrangement, mainly in lamellipodia formation, and that this process was mediated by integrin alpha(V)beta-mediated FAK and PI3K phosphorylation and Rac1 activation.
Furin (show FURIN Antibodies) has a role as the primary in vivo convertase of ANGPTL3 and endothelial lipase (show LIPG Antibodies) in hepatocytes
ANGPTL8, a paralog of ANGPTL3 that arose through duplication of an ancestral DOCK gene, regulates postprandial TAG and fatty acid metabolism by controlling activation of its progenitor, and perhaps other ANGPTLs
Angptl3, as an extrinsic factor, thus supports the stemness of hematopoietic stem cells in the bone marrow niche.
ANGPTL3 expression is upregulated in puromycin-induced podocyte damage and is associated with the reduction of perlecan (show HSPG2 Antibodies) and agrin (show AGRN Antibodies) expression
First report of molecular cloning and characterization of ANGPTL3 in pigs, which will be helpful for a better understanding of the role of ANGPTLs in lipid metabolism.
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
, WITHDRAWN: zgc:111943
, angiopoietin-related protein 3-like
, angiopoietin 5
, angiopoietin-related protein 3
, angiopoietin-like protein 3