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Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. Additionally we are shipping Angiostatin Antibodies (12) and Angiostatin Proteins (10) and many more products for this protein.
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Plasminogen (show PLG ELISA Kits)-deficient mice frequently develop colon lesions and rectal prolapses.
manganese transport protein (show SLC11A2 ELISA Kits) C (show PROC ELISA Kits) (MntC) is an extracellular matrix- and plasminogen-binding protein (show ENO1 ELISA Kits)
Plg (show PLG ELISA Kits) from mouse plasma contains oxPtdPC adducts that are not affected by the action of Lp-PLA(2 (show Lp-PLA2 ELISA Kits)), suggesting that linkage to Plg (show PLG ELISA Kits) protects oxPtdPCs from metabolism during their transport in the plasma.
plg (show PLG ELISA Kits)-/- and tPA (show PLAT ELISA Kits)-/- mice exhibit brain parenchymal fibrin deposits that appear to result from reduced neurovascular integrity
plasminogen (show PLG ELISA Kits)-dependent proteolysis has a beneficial effect during neurological recovery after stroke.
Pla-induced mononuclear cell recruitment in vivo was dependent on protease-activated receptor-1 activation of the MEK/ERK/NF-kappaB pathway, which led to the release of CCL2 and activation of CCR2.
Plg (show PLG ELISA Kits) may play an important role in innate immunity by changing expression of genes that contribute to phagocytosis.
Plasminogen (show PLG ELISA Kits) is a key molecular determinant of inflammatory joint disease capable of simultaneously driving or ameliorating arthritis pathogenesis in distinct anatomic locations in the same subject.
Plasmin (show PLG ELISA Kits) suppresses brain metastasis in two ways: by converting membrane-bound astrocytic FasL (show FASL ELISA Kits) into a paracrine death signal for cancer cells, and by inactivating the axon pathfinding molecule L1CAM (show L1CAM ELISA Kits), which metastatic cells express for spreading along brain capillaries and for metastatic outgrowth.
Plasminogen (show PLG ELISA Kits) stimulates autocrine cytokine production in human airway smooth muscle cells in a manner mediated by plasmin (show PLG ELISA Kits) and annexin A2 (show ANXA2 ELISA Kits).
Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity).
, plasmin heavy chain A
, plasmin light chain B