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Anillin, Actin Binding Protein Proteins (ANLN)

Required for cytokinesis. Additionally we are shipping Anillin Antibodies (53) and Anillin Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ANLN ANLN 307056  
ANLN 54443 Q9NQW6
ANLN 68743 Q8K298
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Top Anillin Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days

ANLN Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Anillin, Actin Binding Protein (ANLN) Interaction Partners

Fruit Fly (Drosophila melanogaster) Anillin, Actin Binding Protein (ANLN) interaction partners

  1. we show that the transition from the actomyosin contractile ring to the midbody ring proceeds via a previously uncharacterized maturation process that requires opposing mechanisms of removal and retention of the scaffold protein (show HOMER1 Proteins) Anillin.

  2. Anillin is required for complete closure of the contractile ring and formation of the midbody ring during cytokinesis.

  3. the anillin pleckstrin (show PLEK Proteins) homology domain has two functions: targeting anillin to the plasma membrane furrow by binding to phosphatidylinositol phosphate lipids to maintain furrow organization and recruiting septins to the furrow.

  4. Data suggest that Cindr and Anillin cooperate to promote intercellular bridge stability during incomplete cytokinesis in Drosophila melanogaster.

  5. Results show that the anillin-septin and cadherin-catenin complexes can serve as alternative cassettes to promote tight physical coupling of F-actin and myosin II to the cleavage furrow and successful completion of cytokinesis.

  6. anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis

  7. important role for scraps in scaffolding cleavage furrow components, directly stabilizing intracellular bridges

  8. A novel RhoGEF(Pbl)-dependent input promotes the simultaneous association of anillin with the plasma membrane, septins, and microtubules, independently of F-actin.

  9. anillin and Peanut are involved in pseudocleavage furrow ingression in syncytial embryos, a process that is regulated by Ran

Human Anillin, Actin Binding Protein (ANLN) interaction partners

  1. High nuclear expression of anillin (ANLN) is an independent predictor of poor disease-specific survival and it is a useful prognostic marker of urothelial carcinoma of the upper urinary tract (UCUT).

  2. Data suggest that anillin (ANLN) could be involved in breast cancer progression and a potential target candidate in breast cancer.

  3. Identification 4 novel and 18 known exonic ANLN variants associated with carotid intima-media thickness at bifurcation.

  4. Anillin regulates intercellular adhesion in model human epithelia by mechanisms involving the suppression of JNK (show MAPK8 Proteins) activity and controlling the assembly of the perijunctional cytoskeleton.

  5. The sequestration of anillin by astral microtubules might alter the organization of cortical proteins to polarize cells for cytokinesis

  6. these data demonstrate that a complex of p190RhoGAP (show GRLF1 Proteins)-A and anillin modulates RhoA (show RHOA Proteins)-GTP (show AK3 Proteins) levels in the cytokinetic furrow to ensure progression of cytokinesis.

  7. Identified a missense mutation R431C in anillin (ANLN), an F-actin binding cell cycle gene, as a cause of FSGS (show ACTN4 Proteins). We screened 250 additional families with FSGS (show ACTN4 Proteins) and found another variant, G618C, that segregates with disease in a second family with FSGS (show ACTN4 Proteins).

  8. ANLN is positively associated with Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling in gastric cancer.Elevated expression of ANLN is a predictor of intestinal type gastric cancer. ER-alpha (show ESR1 Proteins) is negatively associated with the expression of ANLN in gastric cancer.

  9. Supervillin (show SVIL Proteins) concentrates activated and total myosin II at the furrow, and simultaneous knockdown of supervillin (show SVIL Proteins) and anillin additively increases cell division failure.

  10. Antibody screening revealed 3 candidate prognostic markers in breast cancer: the Anillin (ANLN); PDZ-Binding Kinase (PBK (show PBK Proteins)); and, PDZ-Domain Containing 1 (PDZK1 (show PDZK1 Proteins)).

Mouse (Murine) Anillin, Actin Binding Protein (ANLN) interaction partners

  1. Anillin is excluded from the cortex of first polar body, enriched in the cytokinetic ring that severs the polar body from the oocyte. In meiosis II, anillin is enriched in a cortical stripe coincident with and overlying the meiotic spindle midzone.

  2. Results show that targeting of mDia2 (show DIAPH3 Proteins) to the cleavage furrow requires not only its binding to RhoA (show RHOA Proteins) but also its diaphanous-inhibitory domain, and identify anillin as a novel mDia2 (show DIAPH3 Proteins) interaction partner.

Xenopus laevis Anillin, Actin Binding Protein (ANLN) interaction partners

  1. The authors propose that anillin is required for proper Rho-GTP (show AK3 Proteins) distribution at cell-cell junctions and for maintenance of a robust apical actomyosin belt, which is required for cell-cell junction integrity.

  2. anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis

Anillin (ANLN) Protein Profile

Protein Summary

Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression (By similarity).

Gene names and symbols associated with ANLN

  • scraps (scra)
  • anillin, actin binding protein-like 1 (Anlnl1)
  • anillin, actin binding protein (ANLN)
  • anillin, actin binding protein (LOC100351074)
  • anillin, actin binding protein (anln)
  • anillin, actin binding protein (Anln)
  • 1110037A17Rik protein
  • 2900037I21Rik protein
  • Abp8 protein
  • ani protein
  • anil protein
  • anillin protein
  • ANLN protein
  • C78101 protein
  • CG2092 protein
  • Dmel\\CG2092 protein
  • l(2)03427 protein
  • l(2)43Ec protein
  • l(2)k08255 protein
  • RGD1566097 protein
  • scra protein
  • Scraps protein

Protein level used designations for ANLN

Actin-binding protein 8 , CG2092-PA , CG2092-PB , CG2092-PC , anillin , annilin , lethal (2) k08255 , scra-PA , scra-PB , scra-PC , anillin, actin binding protein (scraps homolog, Drosophila) , anillin, actin binding protein , actin-binding protein anillin-like , actin-binding protein anillin , contractile ring component anillin

35696 Drosophila melanogaster
307056 Rattus norvegicus
420738 Gallus gallus
463351 Pan troglodytes
482401 Canis lupus familiaris
518274 Bos taurus
706404 Macaca mulatta
100351074 Oryctolagus cuniculus
100387382 Callithrix jacchus
100469164 Ailuropoda melanoleuca
100329114 Xenopus (Silurana) tropicalis
100548396 Meleagris gallopavo
100558878 Anolis carolinensis
100581939 Nomascus leucogenys
54443 Homo sapiens
68743 Mus musculus
398569 Xenopus laevis
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