Ankylosis, Progressive Homolog (Mouse) (ANKH) ELISA Kits

ANKH encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Additionally we are shipping ANKH Antibodies (33) and ANKH Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ANKH ANKH 56172 Q9HCJ1
Anti-Rat ANKH ANKH 114506 P58366
Anti-Mouse ANKH ANKH 11732 Q9JHZ2
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More ELISA Kits for ANKH Interaction Partners

Pig (Porcine) Ankylosis, Progressive Homolog (Mouse) (ANKH) interaction partners

  1. Data indicate that ankylosis gene product ANK siRNA suppressed basal and hypotonically-stressed ATP levels.

Human Ankylosis, Progressive Homolog (Mouse) (ANKH) interaction partners

  1. Results show that ANK localizes to the trans-Golgi network (TGN), clathrin-coated vesicles and the plasma membrane, and is required for endosomal function and endocytosis

  2. This study validates the association between a functional polymorphism in the 5' UTR (show UTS2R ELISA Kits) of ANKH and Chondrocalcinosis

  3. Polymorphisms in ALP (show ALP ELISA Kits), ENPP1 (show ENPP1 ELISA Kits) and ANKH are important genetic risk factors contributing to Pseudoxanthoma elasticum

  4. ANK (show ANK1 ELISA Kits) was concentrated around crystal deposits and correlated with markers of chondrocyte hypertrophy. These findings support a role for ANK (show ANK1 ELISA Kits) in CPPD crystal formation in cartilage.

  5. expression levels of type II collagen (show COL2A1 ELISA Kits), aggrecan (show ACAN ELISA Kits), and ANK (show ANK1 ELISA Kits) in endplate chondrocytes of experimental group were lower than that of control group and phosphorylation level of JNK (show MAPK8 ELISA Kits) in the experimental group which was higher than that in the control group

  6. Analysis of the present CMD (show ACAN ELISA Kits) family suggested the presence of a maternal mosaicism in an ANKH mutation, and the mother who was mosaic for the ANKH mutation had no apparent clinical or radiological features of CMD (show ACAN ELISA Kits).

  7. The aim of this study was to investigate two mineralization-related genes TNAP and ANKH polymorphisms associated with ankylosing spondylitis (AS) in the North Chinese Han population.

  8. Neither ANKH nor ENPP1 (show ENPP1 ELISA Kits) mutations are the cause of chondrocalcinosis in these Slovakian families.

  9. TNF (show TNF ELISA Kits)-activated NF-kappaB (show NFKB1 ELISA Kits) promotes inflammation-accelerated vascular calcification by inhibiting ankylosis protein homolog expression and consequent pyrophosphate secretion.

  10. We report a novel mutation, not previously described, in ANKH exon 1, wherein serine replaces proline, in a case of early-onset severe calcium pyrophosphate disease associated with metabolic abnormalities, with similar findings in the proband's father

Mouse (Murine) Ankylosis, Progressive Homolog (Mouse) (ANKH) interaction partners

  1. our study provides evidence that ANK plays a critical role in the adipogenic/osteogenic fate decision of adult mesenchymal precursor cells

  2. regulates the transport of inorganic pyrophosphate, and Ank knock-out mice feature a rapidly forming and thick cementum and increased cementum regeneration

  3. Loss of Ank alters cementoblast gene expression and cervical cementum extracellular matrix composition.

  4. the relationship between the type of temporomandibular disorders (TMD (show TTN ELISA Kits)) and ANKH polymorphisms

  5. Phe377del mutation in ANK causes impaired osteoblastogenesis and osteoclastogenesis resulting in hypomineralization and a high bone mass phenotype.

  6. ANK is a positive regulator of osteoblastic and osteoclastic differentiation events toward a mature osteoblastic and osteoclastic phenotype.

  7. Analyses on mineralized tissues showed no decrease in mineralization between ank/ank cementum vs. WT controls. Nanoindentation on enamel, dentin or cementum of ank/ank vs. WT molars revealed no significant difference in hardness and elastic modulus.

  8. endogenous expression of ANKH mRNA and protein in whole mouse kidney as well as mouse renal epithelial cell lines and a osteoblast cell line.

  9. Linked regulatory effects on extracellular PP(i) and OPN (show SPP1 ELISA Kits) expression mediate the ability of PC-1 (show PCSK1 ELISA Kits) and ANK to regulate calcification.

  10. intra-renal and subcellular localisation of ANK is consistent with pyrophosphate export from collecting duct cells and supports a role for ANK in limiting intra-renal calcium-crystal formation

ANKH Antigen Profile

Antigen Summary

This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia.

Gene names and symbols associated with ANKH

  • ANKH inorganic pyrophosphate transport regulator (ANKH) antibody
  • ANKH inorganic pyrophosphate transport regulator S homeolog (ankh.S) antibody
  • ANKH inorganic pyrophosphate transport regulator (Ankh) antibody
  • ANKH inorganic pyrophosphate transport regulator b (ankhb) antibody
  • progressive ankylosis (Ank) antibody
  • Ank antibody
  • Ankh antibody
  • CCAL2 antibody
  • CMDJ antibody
  • CPPDD antibody
  • D15Ertd221e antibody
  • HANK antibody
  • MANK antibody
  • mKIAA1581 antibody
  • wu:fc08d03 antibody

Protein level used designations for ANKH

ankylosis, progressive homolog (mouse) , progressive ankylosis protein , progressive ankylosis protein homolog-like , progressive ankylosis protein homolog , ankylosis, progressive homolog , progressive ankylosis-like protein , progressive ankylosis homolog , ANK-B , progressive ankylosis protein homolog B , fn54 protein

100020529 Monodelphis domestica
100090061 Ornithorhynchus anatinus
100343978 Oryctolagus cuniculus
100400360 Callithrix jacchus
100459252 Pongo abelii
100470006 Ailuropoda melanoleuca
471459 Pan troglodytes
100070193 Equus caballus
100550536 Meleagris gallopavo
100600686 Nomascus leucogenys
100624458 Sus scrofa
399193 Xenopus laevis
56172 Homo sapiens
114506 Rattus norvegicus
420917 Gallus gallus
491486 Canis lupus familiaris
511800 Bos taurus
323738 Danio rerio
11732 Mus musculus
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