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anti-Ankyrin 1, Erythrocytic (ANK1) Antibodies

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Additionally we are shipping Erythrocyte Ankyrin Kits (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANK1 286 P16157
ANK1 306570  
ANK1 11733 Q02357
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Top anti-Erythrocyte Ankyrin Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ANK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: HT1080 cell lysate Host: Rabbit  Target Name: ANK1  Sample Tissue: Human Fetal Liver  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ANK1 Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-ANK1  Antibody Titration: 1.25 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Human Mouse PE ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Human Mouse Streptavidin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Human Mouse PerCP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

ANK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Erythrocyte Ankyrin Antibodies

  1. Cow (Bovine) Polyclonal Erythrocyte Ankyrin Primary Antibody for IHC, WB - ABIN2775478 : Chang, Ruan: Exploration of pressure-induced dissociation of pyruvate oxidase. in Cellular and molecular biology (Noisy-le-Grand, France) 2004 (PubMed)
    Show all 2 references for ABIN2775478

  2. Human Monoclonal Erythrocyte Ankyrin Primary Antibody for ICC, IF - ABIN2485537 : Bennett, Baines: Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. in Physiological reviews 2001 (PubMed)

  3. Human Polyclonal Erythrocyte Ankyrin Primary Antibody for ELISA, WB - ABIN302139 : Dubreuil: Functional links between membrane transport and the spectrin cytoskeleton. in The Journal of membrane biology 2006 (PubMed)

  4. Human Polyclonal Erythrocyte Ankyrin Primary Antibody for WB - ABIN2776925 : Bok, Plazuk, Hryniewicz-Jankowska, Chorzalska, Szmaj, Dubielecka, Stebelska, Diakowski, Lisowski, Langner, Sikorski: Lipid-binding role of betaII-spectrin ankyrin-binding domain. in Cell biology international 2007 (PubMed)

More Antibodies against Erythrocyte Ankyrin Interaction Partners

Pig (Porcine) Ankyrin 1, Erythrocytic (ANK1) interaction partners

  1. Single nucleotide polymorphisms (SNPs) in the ANK1 gene promoter could potentially contribute to genome-assisted selection SNP panels to improve intramuscular fat and water holding capacity on a breed basis.

Human Ankyrin 1, Erythrocytic (ANK1) interaction partners

  1. analysis of a novel p.Q1772X ANK1 mutation in a Korean family with hereditary spherocytosis [case report of two family members]

  2. The study reports the refinement for a protein heterodimer complex using limited EPR (show EREG Antibodies) spectroscopic data and a rigid-body docking algorithm: a three-dimensional model for an ankyrin 1-BND3 (show SLC4A1 Antibodies) complex.

  3. A novel L1340P mutation in the ANK1 gene is associated with hereditary spherocytosis.

  4. Our analyses suggest that these DNA methylation (show HELLS Antibodies) changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network.

  5. We identified a differentially methylated region in the ankyrin 1 (ANK1) gene that was associated with neuropathology in the entorhinal cortex, a primary site of Alzheimer disease manifestation.

  6. ANK1 rs516946 confers impaired insulin (show INS Antibodies) release.

  7. The ankyrin-binding site on band 3 (show SLC4A1 Antibodies) is located near the deoxygenated hemoglobin (show HBB Antibodies)-binding site, therefore following deoxygenation ankyrin is displaced from band 3 (show SLC4A1 Antibodies).

  8. A tissue-specific chromatin loop brings NF-E2 (show NFE2 Antibodies) and ANK1E into close proximity preventing gene silencing and mutagenesis leading to hereditary spherocytosis.

  9. results indicate that the ANK1 locus is a new, common susceptibility locus for type 2 diabetes across different ethnic groups

  10. The interaction of KCTD6 with ankyrin-1 may have implications beyond muscle for hereditary spherocytosis, as KCTD6 is also present in erythrocytes, and erythrocyte ankyrin isoforms contain its mapped minimal binding site.

Mouse (Murine) Ankyrin 1, Erythrocytic (ANK1) interaction partners

  1. With increasing age (at 12-15 mo of age) extensor digitorum longus (EDL (show LIPG Antibodies)) skeletal muscles of sAnk1 KO mice develop prematurely large tubular aggregates.

  2. Study shows a direct interaction between beta-III spectrin (show SPTBN2 Antibodies) and erythroid ankyrin in the cerebellum and to demonstrate a critical role for beta-III spectrin (show SPTBN2 Antibodies) in maintaining ankyrin R throughout the Purkinje cell dendritic tree.

  3. Hema6 mutation of ankyrin-1 causes hereditary spherocytosis in mice through a mild reduction of protein expression.

  4. Suppression of hepcidin (show HAMP Antibodies) expression and iron overload mediate Salmonella susceptibility in ankyrin 1-mutated mice.

  5. We conclude that increased malaria resistance due to ankyrin-1 deficiency is caused by the intraerythrocytic death of P. chabaudi parasites.

  6. These results demonstrate that mammalian erythroblast enucleation does not depend on the membrane integrity generated by the ankyrin-band 3 (show SLC4A1 Antibodies) complex.

  7. The Ank1(E924X) strain provides a novel tool to study Ank1 and model HS.

  8. A spontaneous mutation, normoblastosis (Ank1nb) in mice provides an important animal model for human ankyrin-deficient anemias.

  9. Results support a role of obscurin (show OBSCN Antibodies) in mediating the subcellular localization of small ankyrin1 isoforms in striated (show NSDHL Antibodies) muscle cells.

  10. the organization of obscurin (show OBSCN Antibodies) at different locations in the sarcomere changes during muscle development and that this might affect the interaction with ank1.5.

Erythrocyte Ankyrin (ANK1) Antigen Profile

Protein Summary

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified.

Gene names and symbols associated with ANK1

  • ankyrin 1, erythrocytic (ANK1) antibody
  • ankyrin 1, erythrocytic (ank1) antibody
  • ankyrin 1, erythrocytic (Ank1) antibody
  • ankyrin 1, erythroid (Ank1) antibody
  • ANK antibody
  • Ank-1 antibody
  • ANK1 antibody
  • CHANK1 antibody
  • nb antibody
  • pale antibody
  • SPH1 antibody
  • SPH2 antibody
  • wu:fa09h06 antibody
  • zgc:101835 antibody

Protein level used designations for ANK1

ankyrin 1, erythrocytic , erythroid ankyrin , ankyrin-1-like , ANK-1 , ankyrin-1 , ankyrin-R , erythrocyte ankyrin , ankyrin 1, erythroid , normoblastic anemia

GENE ID SPECIES
396311 Gallus gallus
449796 Danio rerio
613080 Xenopus (Silurana) tropicalis
736634 Pan troglodytes
100036926 Xenopus laevis
100055459 Equus caballus
100388861 Callithrix jacchus
100482591 Ailuropoda melanoleuca
100155697 Sus scrofa
286 Homo sapiens
353108 Bos taurus
306570 Rattus norvegicus
482842 Canis lupus familiaris
11733 Mus musculus
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