Ankyrin Repeat-Containing Protein Proteins (EHMT2)

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. Additionally we are shipping EHMT2 Antibodies (63) and EHMT2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat EHMT2 EHMT2 361798  
EHMT2 110147 Q9Z148
EHMT2 10919 Q96KQ7
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Top EHMT2 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Baculovirus Human DYKDDDDK Tag Recombinant G9a protein gel. G9a protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. 20 μg Log in to see 1 to 2 Days
$466.67
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$365.64
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 1 to 2 Days
$466.67
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 1 to 2 Days
$466.67
Details

EHMT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , ,
, , ,

More Proteins for Ankyrin Repeat-Containing Protein (EHMT2) Interaction Partners

Arabidopsis thaliana Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. These results suggest that PIA2 modulates phyA-mediated PIF3 phosphorylation by physical interaction with PIF3 and that the secondary structure of the PIA2 N-terminus is important in this modulation.

  2. Data indicate protein kinases FLS2 and BAK1 (show BAK1 Proteins) contribute to autoimmune signaling in ACCELERATED CELL DEATH6 (ACD6) L591F amino acid substitution.

  3. Here we show instead that hybrid necrosis can be triggered by interactions between variants of a single gene, ACD6 (ACCELERATED CELL DEATH 6).

  4. The effects of mutation on the structure and function of ACD6 in response to salicylic acid and disease resistance are reported.

Mouse (Murine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. The findings of this study suggested that G9a participates in the nerve injury-induced reduction of the Oprm1 gene likely through G9a-triggered blockage in the access of cyclic AMP response element binding protein to this gene.

  2. GLP/G9a H3K9 methyltransferase complex is an enzyme counteracting Jmjd1a (show KDM3A Proteins)-mediated H3K9 demethylation at the Sry (show SRY Proteins) locus in gonadal somatic cells

  3. G9a regulates cell proliferation and timing of differentiation and that G9a expression in the tooth mesenchyme is required for proper tooth development

  4. Jmjd2c (show KDM4C Proteins) and G9a are novel enhancer-associated factors. Loss of Jmjd2c (show KDM4C Proteins) abrogates G9a recruitment and further destabilises loading of the mediator and cohesin components Med1 (show MBD4 Proteins) and Smc1a (show SMC1A Proteins) at newly activated and poised enhancers in embryonic stem cell-derived epiblast-like cells.

  5. G9a is an important regulator in placental diseases caused by defective vascular maturation.

  6. miR (show MLXIP Proteins)-217-mediated, genetic, or pharmacological inactivation of EHMT1 (show EHMT1 Proteins)/2 was sufficient to promote pathological hypertrophy

  7. G9A overexpression is associated with peritoneal fibrosis.

  8. high levels of G9a-dependent H3K9me2 at ILC3-specific genetic loci, demonstrating that G9a-mediated repression of ILC3-associated genes is critical for the optimal development of ILC2s.

  9. G9a functions both as a co-activator and a co-repressor to enhance cellular proliferation and inhibit myogenic differentiation.

  10. GLP, but not G9a, inhibits proteasome subunit-encoding genes expression.

Human Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. G9a inhibition impairs anchorage-dependent and -independent cell growth in hepatocellular carcinoma cells

  2. A histone H3K9-like mimic within LIG1 (show LIG1 Proteins) is methylated by G9a and GLP (show RCBTB1 Proteins) and avidly binds UHRF1 (show UHRF1 Proteins). Interaction with methylated LIG1 (show LIG1 Proteins) promotes the recruitment of UHRF1 (show UHRF1 Proteins) to DNA replication sites and is required for DNA methylation (show HELLS Proteins) maintenance.

  3. G9a is an important regulator in placental diseases caused by defective vascular maturation.

  4. Low G9a expression is associated with lung and colonic cancer.

  5. G9A overexpression is associated with peritoneal fibrosis.

  6. G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 (show TP53 Proteins) status.

  7. Inhibition of EZH2 (show EZH2 Proteins) (by GSK-343 or EPZ-6438) or inhibition of EHMT2 (by UNC-0638) in the Th17 primary cell model of HIV latency or resting memory T cells isolated from HIV-1-infected patients receiving highly active antiretroviral therapy, was sufficient to induce the reactivation of latent proviruses.

  8. we find an estrogen receptor-independent synthetic lethal interaction between a GATA3 frameshift mutant with an extended C-terminus and the histone methyltransferases G9A and GLP, indicating perturbed epigenetic regulation

  9. High expression of G9a and H3K9me2 in glioma tissue samples was associated with the WHO grade, which indicated that G9a and H3K9me2 may promote generation and development of glioma. BIX01294 may be a potential novel therapeutic agent in the treatment of glioma.

  10. Depletion of G9a inhibits cell growth and induces cells apoptosis in gastric cancer.

Pig (Porcine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. EHMT2 inhibitor BIX-01294 is a potent inhibitor of H3K9 dimethylation and transient alterations in global histone modifications can have profound effects on embryo developmental potential.

EHMT2 Protein Profile

Protein Summary

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster\; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.

Gene names and symbols associated with EHMT2

  • ankyrin repeat-containing protein (ank1)
  • ankyrin repeat-containing protein (IscW_ISCW006888)
  • ankyrin repeat-containing protein (Arnit_2917)
  • ankyrin repeat-containing protein (AT3G04470)
  • ankyrin repeat-containing protein (AT4G14390)
  • protein accelerated cell death 6 (ACD6)
  • ankyrin repeat-containing protein (AT4G19150)
  • ankyrin repeat-containing protein (AT4G03500)
  • ankyrin repeat-containing protein (AT4G03450)
  • ankyrin repeat-containing protein (AT4G03460)
  • ankyrin repeat-containing protein (AT4G03440)
  • ankyrin repeat-containing protein (AT5G07840)
  • ankyrin repeat-containing protein (AT5G12320)
  • ankyrin repeat-containing protein (AT5G15500)
  • ankyrin repeat-containing protein (AT5G51160)
  • ankyrin repeat-containing protein (AT5G54620)
  • ankyrin repeat-containing protein (AT5G60070)
  • phytochrome interacting ankyrin-repeat protein 2 (AT5G61230)
  • ankyrin repeat-containing protein (AT1G04780)
  • ankyrin repeat-containing protein (AT1G62050)
  • euchromatic histone lysine N-methyltransferase 2 (Ehmt2)
  • euchromatic histone-lysine N-methyltransferase 2 (EHMT2)
  • ACCELERATED CELL DEATH 6 protein
  • BAT8 protein
  • C6orf30 protein
  • D17Ertd710e protein
  • DL3235W protein
  • DL3240W protein
  • F9H3.6 protein
  • F9H3.7 protein
  • F9H3.9 protein
  • F9H3.13 protein
  • F9H3_6 protein
  • F9H3_7 protein
  • F9H3_9 protein
  • F9H3_13 protein
  • F13G24.40 protein
  • FCAALL.188 protein
  • FCAALL.190 protein
  • G9A protein
  • GAT8 protein
  • KMT1C protein
  • MAF19.22 protein
  • MAF19_22 protein
  • MGO3.5 protein
  • MGO3_5 protein
  • MRB17.12 protein
  • MRB17_12 protein
  • MWD22.10 protein
  • MWD22_10 protein
  • NG36 protein
  • T18B16.120 protein
  • T18B16_120 protein
  • T20K14.110 protein
  • T20K14_110 protein
  • T27C4.12 protein
  • T27C4_12 protein

Protein level used designations for EHMT2

ankyrin repeat-containing protein , HLA-B associated transcript 8, rat orthologue , euchromatic histone-lysine N-methyltransferase 2 , histone-lysine N-methyltransferase, H3 lysine-9 specific 3 , H3-K9-HMTase 3 , HLA-B associated transcript 8 , HLA-B-associated transcript 8 , histone H3-K9 methyltransferase 3 , histone-lysine N-methyltransferase EHMT2 , protein G9a , G9A histone methyltransferase , lysine N-methyltransferase 1C

GENE ID SPECIES
4606933 Azoarcus sp. BH72
8032296 Ixodes scapularis
9173113 Arcobacter nitrofigilis DSM 7299
819603 Arabidopsis thaliana
827084 Arabidopsis thaliana
827085 Arabidopsis thaliana
827653 Arabidopsis thaliana
827731 Arabidopsis thaliana
827913 Arabidopsis thaliana
827916 Arabidopsis thaliana
827920 Arabidopsis thaliana
830677 Arabidopsis thaliana
831107 Arabidopsis thaliana
831403 Arabidopsis thaliana
835190 Arabidopsis thaliana
835551 Arabidopsis thaliana
836129 Arabidopsis thaliana
836244 Arabidopsis thaliana
839414 Arabidopsis thaliana
842501 Arabidopsis thaliana
361798 Rattus norvegicus
110147 Mus musculus
10919 Homo sapiens
474851 Canis lupus familiaris
100124382 Sus scrofa
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