anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) Antibodies

Acts as a calcium-activated chloride channel. Additionally we are shipping ANO1 Proteins (8) and ANO1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANO1 55107 Q5XXA6
ANO1 101772 Q8BHY3
ANO1 309135  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-ANO1 Antibodies at antibodies-online.com

Showing 10 out of 339 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) 1 mL Log in to see 2 to 3 Days
$705.00
Details
Human Mouse Un-conjugated IHC, IHC (fro), IHC (p) Immunohistochemistry-Paraffin: DOG1/TMEM16A Antibody (DOG1.1) [NBP1-49559] - Gastrointestinal stromal tumor tissue. Immunohistochemistry-Paraffin: DOG1/TMEM16A Antibody (DOG1.1) [NBP1-49559] - FFPE gastrointestinal stromal tumor stained with D0G1 antibody. 6 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Rat Rabbit Un-conjugated WB Observed bind size: 114KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$242.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$308.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry: DOG1/TMEM16A Antibody [NBP1-60076] - Human Liver Antibody Dilution: 0.2 ug/ml. Western Blot: DOG1/TMEM16A Antibody [NBP1-60076] - Human Muscle lysate, concentration 0.2-1 ug/ml. 50 μL Log in to see 7 to 9 Days
$500.06
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat heart tissue labeled with Rabbit Anti-DOG-1/TMEM16A Polyclonal Antibody, Unconjugated (ABIN704216) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat heart tissue labeled with Rabbit Anti-DOG-1/TMEM16A Polyclonal Antibody, Unconjugated (ABIN704216) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated IHC (p) Formalin-Fixed Paraffin-Embedded gastrointestinal stromal tumor staiend with D0G1 Antibody Cat.-No AM09094SU (Clone DOG1.1). 0.5 mL Log in to see 6 to 8 Days
$324.50
Details

ANO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , ,


, , , , , , , , , , , , ,
Rat (Rattus) , , ,


, , , , , , , , , , , , ,

Top referenced anti-ANO1 Antibodies

  1. Human Monoclonal ANO1 Primary Antibody for IHC (p) - ABIN1689062 : Michelucci, Chiappetta, Cacciotti, Veccia, Astri, Leopizzi, Prosperi Porta, Petrozza, Della Rocca, Bevilacqua, Cavazzana, Di Cristofano: The KIT Exon 11 Stop Codon Mutation in Gastrointestinal Stromal Tumors: What Is the Clinical Meaning? in Gut and liver 2013 (PubMed)
    Show all 26 Pubmed References

  2. Human Monoclonal ANO1 Primary Antibody for IHC, IHC (fro) - ABIN4305778 : Namkung, Yao, Finkbeiner, Verkman: Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal ANO1 Primary Antibody for WB - ABIN2775453 : Katoh, Katoh: Identification and characterization of TMEM16E and TMEM16F genes in silico. in International journal of oncology 2004 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal ANO1 Primary Antibody for IHC, WB - ABIN4305781 : Li, Wang, Chen, Jiang, Tu, Li, Yin: TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway. in Molecular medicine reports 2016 (PubMed)

  5. Human Polyclonal ANO1 Primary Antibody for ELISA, ICC - ABIN4305784 : Banga, Flaig, Lewis, Winfree, Blazer-Yost: Epinephrine stimulation of anion secretion in the Calu-3 serous cell model. in American journal of physiology. Lung cellular and molecular physiology 2014 (PubMed)

More Antibodies against ANO1 Interaction Partners

Guinea Pig Anoctamin 1, Calcium Activated Chloride Channel (ANO1) interaction partners

Human Anoctamin 1, Calcium Activated Chloride Channel (ANO1) interaction partners

  1. TMEM16A expression was enhanced by 24-h treatment of IL-4 (show IL4 Antibodies) in human nasal epithelial cells.

  2. findings demonstrate that Ca2 (show CA2 Antibodies)+ influx via store-operated CRAC channels is essential for CaCC (show CLCA1 Antibodies) activation, chloride secretion, and sweat production in humans and mice.

  3. TMEM16A activation as a sequential, direct, and Vm-dependent binding.

  4. Ano1(0) without EAVK [Ano1(0)DeltaEAVK] has reduced sensitivity for intracellular calcium, attributable to slower kinetics. Differential expression of EAVK may function as a calcium-sensitive switch in the human stomach.

  5. Gains of ANO1 is associated with oropharyngeal squamous cell carcinoma.

  6. DOG1 is a novel marker for identifying intercellular canaliculi and is a potential immunomarker of myoepithelial cells specific to mammary glands, anogenital mammary-like glands and tumors originating therein.

  7. Increase in TMEM16A activity occurred within minutes of exposure to CLCA1 (show CLCA1 Antibodies) or after a short treatment with nocodazole, consistent with the hypothesis that CLCA1 (show CLCA1 Antibodies) stabilizes TMEM16A at the cell surface by preventing its internalization.

  8. These results suggest that ANO1 Cl(-) channels may function as a transcriptional regulator of HER2 (show ERBB2 Antibodies), and ANO1 inhibitors have potential in the treatment of BCA (show BLNK Antibodies) patients with resistance to HER2 (show ERBB2 Antibodies)-targeted therapy.

  9. Endogenous ANO1 was associated with COPB1 (show COPB1 Antibodies) in U251 glioblastoma cells, and silencing of COPB1 (show COPB1 Antibodies) enhanced surface expression and whole-cell currents of ANO1 in these cells. Taken together, these data suggest that COPB1 (show COPB1 Antibodies) negatively regulates ANO1 surface expression.

  10. targeting TMEM16A improves response to biological therapies targeting EGFR (show EGFR Antibodies)/HER family members

Mouse (Murine) Anoctamin 1, Calcium Activated Chloride Channel (ANO1) interaction partners

  1. ANO1 immunoreactivity was observed in the presynaptic terminals of various retinal neurons, including photoreceptors

  2. In this work we demonstrate that increasing the extracellular proton concentration from 10-10 to 10-5.5 m enabled TMEM16A activation. Furthermore, we show that this effect is voltage independent, caused by changes in the apparent open probability of the channel, and due to protonation of extracellular residue E623

  3. The present study shows that ANO1 and CavL play a central role in the generation of slow waves, phasic contractions and tone in the internal anal sphincter and that this pathway can occur in the absence of stretch

  4. findings demonstrate that Ca2 (show CA2 Antibodies)+ influx via store-operated CRAC channels is essential for CaCC (show CLCA1 Antibodies) activation, chloride secretion, and sweat production in humans and mice.

  5. We knocked out Ano1 to varying degrees in interstitial cells of Cajal (ICC) of adult mice. Partial knockout of Ano1 shortened the widths of electrical slow waves and Ca(2 (show CA2 Antibodies)+) transients in myenteric ICC but Ca(2 (show CA2 Antibodies)+) transient synchronicity was preserved. Near-complete knockout was necessary for transient desynchronization and loss of slow waves, indicating a large functional reserve of Ano1 in ICC.

  6. Phosphorylation levels of P38 (show CRK Antibodies) and JNK (show MAPK8 Antibodies) in siRNA-TMEM16A group were lower than that of the Model group. Thus, TMEM16A is one of the critical components of a signal transduction pathway that links renal injury to podocyte apoptosis in DN.

  7. To determine the role of ANO1 in physiological functions.

  8. ANO1/TMEM16A is a significant pathway in pancreatic acinar cells for HCO3 (-) secretion into the lumen.

  9. TMEM16A is a positive regulator of endothelial reactive oxygen species generation via Nox2 (show CYBB Antibodies)-containing NADPH oxidase (show NOX1 Antibodies), which induces endothelial dysfunction and hypertension.

  10. Data indicate that anoctamin channel proteins ANO1 and ANO2 (show ANO2 Antibodies) are expressed in the cerebellum.

ANO1 Antigen Profile

Protein Summary

Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).

Gene names and symbols associated with ANO1

  • anoctamin 1, calcium activated chloride channel (Ano1) antibody
  • anoctamin 1, calcium activated chloride channel (ANO1) antibody
  • DOG1 antibody
  • ORAOV2 antibody
  • TAOS2 antibody
  • Tmem16a antibody

Protein level used designations for ANO1

anoctamin 1, calcium activated chloride channel , Ca-activated chloride channel Tmem16A , anoctamin-1 , discovered on gastrointestinal stromal tumors protein 1 , oral cancer overexpressed 2 , transmembrane protein 16A (eight membrane-spanning domains) , tumor-amplified and overexpressed sequence 2 , transmembrane protein 16A

GENE ID SPECIES
100529098 Cavia porcellus
55107 Homo sapiens
423144 Gallus gallus
532126 Bos taurus
101772 Mus musculus
309135 Rattus norvegicus
611698 Canis lupus familiaris
Selected quality suppliers for anti-ANO1 (ANO1) Antibodies
Did you look for something else?