Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Acts as a calcium-activated chloride channel. Additionally we are shipping ANO1 Proteins (8) and ANO1 Kits (1) and many more products for this protein.
Showing 10 out of 316 products:
Human Monoclonal ANO1 Primary Antibody for IHC (p) - ABIN1689062
Michelucci, Chiappetta, Cacciotti, Veccia, Astri, Leopizzi, Prosperi Porta, Petrozza, Della Rocca, Bevilacqua, Cavazzana, Di Cristofano: The KIT Exon 11 Stop Codon Mutation in Gastrointestinal Stromal Tumors: What Is the Clinical Meaning? in Gut and liver 2013
Show all 26 references for ABIN1689062
Human Polyclonal ANO1 Primary Antibody for EIA, IF - ABIN500970
Rock, Futtner, Harfe: The transmembrane protein TMEM16A is required for normal development of the murine trachea. in Developmental biology 2008
Show all 5 references for ABIN500970
Human Monoclonal ANO1 Primary Antibody for IHC, IHC (fro) - ABIN4305778
Namkung, Yao, Finkbeiner, Verkman: Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011
Show all 2 references for ABIN4305778
Human Polyclonal ANO1 Primary Antibody for IHC, WB - ABIN4305781
Li, Wang, Chen, Jiang, Tu, Li, Yin: TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway. in Molecular medicine reports 2016
Human Polyclonal ANO1 Primary Antibody for EIA, WB - ABIN493518
Caputo, Caci, Ferrera, Pedemonte, Barsanti, Sondo, Pfeffer, Ravazzolo, Zegarra-Moran, Galietta: TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. in Science (New York, N.Y.) 2008
Chicken Polyclonal ANO1 Primary Antibody for WB - ABIN2775453
Katoh, Katoh: Identification and characterization of TMEM16E and TMEM16F genes in silico. in International journal of oncology 2004
Increase in TMEM16A activity occurred within minutes of exposure to CLCA1 (show CLCA1 Antibodies) or after a short treatment with nocodazole, consistent with the hypothesis that CLCA1 (show CLCA1 Antibodies) stabilizes TMEM16A at the cell surface by preventing its internalization.
These results suggest that ANO1 Cl(-) channels may function as a transcriptional regulator of HER2 (show ERBB2 Antibodies), and ANO1 inhibitors have potential in the treatment of BCA (show BLNK Antibodies) patients with resistance to HER2 (show ERBB2 Antibodies)-targeted therapy.
Endogenous ANO1 was associated with COPB1 (show COPB1 Antibodies) in U251 glioblastoma cells, and silencing of COPB1 (show COPB1 Antibodies) enhanced surface expression and whole-cell currents of ANO1 in these cells. Taken together, these data suggest that COPB1 (show COPB1 Antibodies) negatively regulates ANO1 surface expression.
targeting TMEM16A improves response to biological therapies targeting EGFR (show EGFR Antibodies)/HER family members
STAT6 (show STAT6 Antibodies)-TMEM16A-ERK1/2 (show MAPK1/3 Antibodies) signal pathway and TMEM16A channel activity are required for the IL-13 (show IL13 Antibodies)-induced TMEM16A mediated mucus production
DOG1 positivity was detected in most gastrointestinal stromal tumors and its overexpression was related with adverse prognosis
DOG1 positivity might be a candidate marker to support KIT and PDGFRA (show PDGFRA Antibodies) mutations.
Results showed that DOG1 expression was consistently positive in breast myoepithelial cells (MEC (show CCL28 Antibodies)), and is then a useful MEC (show CCL28 Antibodies) marker providing more sophisticated information when diagnosing uncertain cases in the breast.
ANO1 on ICCs makes a key contribution to generation and regulation of pacemaker electrical slow-wave activity.
Data show that calcium-activated chloride channel TMEM16 overexpression correlates with decreased survival in human papilloma virus -negative tumors.
To determine the role of ANO1 in physiological functions.
ANO1/TMEM16A is a significant pathway in pancreatic acinar cells for HCO3 (-) secretion into the lumen.
TMEM16A is a positive regulator of endothelial reactive oxygen species generation via Nox2 (show CYBB Antibodies)-containing NADPH oxidase (show NOX1 Antibodies), which induces endothelial dysfunction and hypertension.
Data indicate that anoctamin channel proteins ANO1 and ANO2 (show ANO2 Antibodies) are expressed in the cerebellum.
Ano1 may play a role in the pathophysiological processes during ischaemia in heart, and therefore, Ano1 might be a potential therapeutic target to prevent ischaemic damage
Thegenetic ablation of TMEM16A did not seem to affect the maturation of olfactory sensory neurons and their ciliary layer.
Suggest Ca(2 (show CA2 Antibodies)+)-dependent push-pull conformational change as a key electromechanical movement for gating the ANO1 channel.
These results indicate ANO1 channels are involved with TRPV1 (show TRPV1 Antibodies) actions in sensory neurons and inhibition of ANO1 could be a novel means of inducing analgesia.
Basolateral Ano1 supports CCH-induced Ca2 (show CA2 Antibodies)+ signaling and secretion via luminal CFTR (show CFTR Antibodies).
By inhibiting TRPM7 (show TRPM7 Antibodies) and ANO1 via opioid receptor signaling pathways.
Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).
anoctamin 1, calcium activated chloride channel
, Ca-activated chloride channel Tmem16A
, discovered on gastrointestinal stromal tumors protein 1
, oral cancer overexpressed 2
, transmembrane protein 16A (eight membrane-spanning domains)
, tumor-amplified and overexpressed sequence 2
, transmembrane protein 16A