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May act as a calcium-activated chloride channel (By similarity).. Additionally we are shipping ANO3 Antibodies (30) and ANO3 Kits (8) and many more products for this protein.
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This study demonstrated that Mutations in ANO3 may cause Dystonia.
rat Ano3 (also known as Tmem16c) interacts with, and alters the activity of the sodium-activated potassium channel Slack (show KCNT1 Proteins). Reduced expression of Ano3 in rat models results in increased pain sensitivity.
ANO3 causes a varied phenotype of young-onset or adult-onset craniocervical dystonia with tremor and/or myoclonic jerks
Low frequency missense variants in ANO3 occur in both cases and controls, warranting further assessment of this gene in primary torsion dystonia pathogenesis.
Our findings indicate that rare exonic variants in ANO3 do not play a major role in the development of essentail tremor
Mutations in ANO3 are a cause of autosomal-dominant craniocervical dystonia.
The significant single nucleotide polymorphisms are located within the overlapping anoctamin 3 (ANO3) and mucin 15 (MUC15 (show MUC15 Proteins)) genes.
C11orf25, FLJ10261 (ORAOV2 (show ANO1 Proteins)), C12orf3 (show ANO2 Proteins) and FLJ34272 constitute a family of eight-transmembrane proteins with N- and C-terminal tails facing the cytoplasm.
Data report the expression of Tmem16c during murine embryogenesis with an emphasis on the respiratory, digestive, skeletal, and integumentary systems.
May act as a calcium-activated chloride channel (By similarity).
, transmembrane protein 16C
, transmembrane protein 16C (eight membrane-spanning domains)