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Anoctamin 6 Proteins (ANO6)

ANO6 encodes a multi-pass transmembrane protein that belongs to the anoctamin family. Additionally we are shipping Anoctamin 6 Antibodies (32) and Anoctamin 6 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANO6 105722 Q6P9J9
Rat ANO6 ANO6 315272  
ANO6 196527 Q4KMQ2
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Top Anoctamin 6 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details

ANO6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Anoctamin 6 (ANO6) Interaction Partners

Mouse (Murine) Anoctamin 6 (ANO6) interaction partners

  1. ANO6 produces volume-regulated anion currents and controls cell volume in four unrelated cell types.

  2. deficiency in Ano6 resulted in reduced viability with increased bleeding time

  3. Although broadly expressed, Ano6 has no role in intestinal cholinergic Cl- secretion.

  4. Ano6 mediates effects essential for innate immunity downstream of P2X7 (show P2RX7 Proteins) receptors in macrophages.

  5. TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets.

  6. Ano6 and Ano2 (show ANO2 Proteins) proteins co-localize in the ciliary membrane microdomains, which indicates a role for Ano6 in olfactory signaling.

  7. human osteoblasts and osteoblasts from Ano6(-/-) and WT mice, we demonstrate that NCX1 requi (show SLC8A1 Proteins)res Ano6 to efficiently translocate Ca(2+) out (show CA2 Proteins) of osteoblasts into the calcifying bone matrix

  8. Ano6 plays an essential role in C2C12 myoblast proliferation

  9. findings show TMEM16A (show ANO1 Proteins) and TMEM16F have an important function in cell migration-TMEM16A (show ANO1 Proteins) in directional migration, TMEM16F in determination of speed of migration; conclude that TMEM16A (show ANO1 Proteins) and TMEM16F channels have a distinct impact on steering and motor mechanisms of migrating ELA cells

  10. TMEM16A (show ANO1 Proteins) and -16F use a similar mechanism for sorting to plasma membrane and protein stabilization, but their functional domains significantly differ

Human Anoctamin 6 (ANO6) interaction partners

  1. Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms

  2. deficiency in Ano6 resulted in reduced viability with increased bleeding time

  3. ANO6 is highly expressed in apoptotic cyst epithelial cells of human polycystic kidneys.

  4. Homology modeling shows that the scramblase domain forms an unusual hydrophilic cleft that faces the lipid bilayer and may function to facilitate translocation of phospholipid between membrane leaflets.

  5. Ano6 mediates effects essential for innate immunity downstream of P2X7 (show P2RX7 Proteins) receptors in macrophages.

  6. using human osteoblasts and osteoblasts from Ano6(-/-) and WT mice, we demonstrate that NCX1 (show SLC8A1 Proteins) requires Ano6 to efficiently translocate Ca(2 (show CA2 Proteins)+) out of osteoblasts into the calcifying bone matrix

  7. TMEM16A (show ANO1 Proteins) and -16F use a similar mechanism for sorting to plasma membrane and protein stabilization, but their functional domains significantly differ

  8. Anoo6 induces a chloride ion conductance along with a smaller nonselective cation conductance that is activated either calcium ion dependently (ionomycin) or calcium independently(fas receptor (show FAS Proteins)), but not during mitochondrial apoptosis.

  9. TMEM16F is an essential component of a divalent calcium ion-activated Cl- channel with a divalent calcium ion sensitivity that is distinct from that of TMEM16A (show ANO1 Proteins)/B and not related to volume-sensitive outwardly rectifying Cl- channel (VSOR) activity.

  10. Study identified 2 novel mutations in the TMEM16F gene in 2 patients with Scott syndrome.

Anoctamin 6 (ANO6) Protein Profile

Protein Summary

This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Anoctamin 6 Proteins (ANO6)

  • anoctamin 6 (ANO6)
  • anoctamin 6 (LOC100337802)
  • anoctamin 6 (ano6)
  • anoctamin 6 (Ano6)
  • 2900059G15Rik protein
  • AA407480 protein
  • AW554778 protein
  • BDPLT7 protein
  • F730003B03Rik protein
  • SCTS protein
  • Tmem16f protein

Protein level used designations for Anoctamin 6 Proteins (ANO6)

anoctamin 6 , transmembrane protein 16F , abnormal X segregation-like , Transmembrane protein 16F , anoctamin-6-like , SCAN channel , anoctamin-6 , small-conductance calcium-activated nonselective cation channel

GENE ID SPECIES
451845 Pan troglodytes
486597 Canis lupus familiaris
521784 Bos taurus
701540 Macaca mulatta
100084251 Ornithorhynchus anatinus
100155593 Sus scrofa
100227071 Taeniopygia guttata
100337802 Oryctolagus cuniculus
100449080 Pongo abelii
100467950 Ailuropoda melanoleuca
100486935 Xenopus (Silurana) tropicalis
100555469 Anolis carolinensis
100599841 Nomascus leucogenys
105722 Mus musculus
315272 Rattus norvegicus
196527 Homo sapiens
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