anti-Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) Antibodies

Required for MUC2 post-transcriptional synthesis and secretion. Additionally we are shipping AGR2 Kits (28) and AGR2 Proteins (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGR2 10551 O95994
AGR2 23795 O88312
AGR2 298961  
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Top anti-AGR2 Antibodies at antibodies-online.com

Showing 10 out of 183 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Host: Rabbit <br /> Target Name: AGR2 <br /> Sample Tissue: Fetal MuscleLane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/laneGel Concentration:.12 % 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB AGR2 Antibody (N-term) (ABIN657766) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the AGR2 antibody detected the AGR2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-AGR2 Antibody (Center) (ABIN390227) in NCI-H460 cell line lysates (35 µg/lane). AGR2(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of AGR2(arrow) using rabbit polyclonal AGR2 Antibody (Center) (ABIN390227).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the AGR2 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of AGR2 Antibody (N-term) in T47D cell line lysates (35 µg/lane). AGR2 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of AGR2(arrow) using rabbit polyclonal AGR2 Antibody (N-term) (ABIN390226).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the AGR2 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334341 (0.01µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$340.00
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details

AGR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-AGR2 Antibodies

  1. Human Monoclonal AGR2 Primary Antibody for ELISA, WB - ABIN564604 : Zhao, Lee, Brown, Molloy, Marx, Pavlakis, Boyer, Stockler, Kaplan, Breit, Sutherland, Henshall, Horvath: Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling. in Cancer research 2009 (PubMed)
    Show all 9 Pubmed References

  2. Polyclonal AGR2 Primary Antibody for IHC (p) - ABIN540789 : Petek, Windpassinger, Egger, Kroisel, Wagner: Localization of the human anterior gradient-2 gene (AGR2) to chromosome band 7p21.3 by radiation hybrid mapping and fluorescencein situ hybridisation. in Cytogenetics and cell genetics 2000 (PubMed)
    Show all 2 Pubmed References

  3. Polyclonal AGR2 Primary Antibody for IHC (p) - ABIN540424 : Fletcher, Patel, Tyson, Adam, Schenker, Loader, Daviet, Legrain, Parekh, Harris, Terrett: hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. in British journal of cancer 2003 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal AGR2 Primary Antibody for ELISA, WB - ABIN523969 : Bergström, Berg, Rodríguez-Piñeiro, Stecher, Johansson, Hansson: AGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucus. in PLoS ONE 2014 (PubMed)

More Antibodies against AGR2 Interaction Partners

Zebrafish Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. Agr2 is essential for terminal differentiation of intestinal goblet cells in zebrafish embryos

  2. Both phylogenetic and syntenic analyses indicate that zebrafish agr2 is the orthologue of human AGR2 and mouse Agr2 genes.

Human Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. The authors conclude that extracellular AGR2 plays an extracellular role independent of its endoplasmic reticulum function and elucidate this gain-of-function as a novel and unexpected critical extracellular matrix microenvironmental pro-oncogenic regulator of epithelial morphogenesis and tumorigenesis.

  2. High AGR2 expression is associated with ovarian cancer.

  3. This study demonstrates that AGR2, which is overexpressed in a variety of human cancers and provides a poor prognosis, up-regulates DUSP10 (show DUSP10 Antibodies) which subsequently inhibits p38 MAPK (show MAPK14 Antibodies) and prevents p53 (show TP53 Antibodies) activation by phosphorylation.

  4. A direct impact of mTOR (show FRAP1 Antibodies) signalling on AGR2 3'UTR (show UTS2R Antibodies) shortening associated with increased protein synthesis was found, which led to the identification of a novel molecular mechanism involved in upregulation of AGR2 levels in mTOR (show FRAP1 Antibodies)-activated cells via modulating the 3'UTR (show UTS2R Antibodies) length of AGR2 mRNA.

  5. Suggest elevated AGR2 as a candidate tamoxifen-dependent mechanism of action responsible for increased incidence of endometrial cancer.

  6. AGR2 could also be upregulated in hormone-independent manner. AGR2 expression was shown to be significantly increased in HER2 (show ERBB2 Antibodies) positive breast tumors on both the mRNA and the protein level.

  7. Our findings demonstrated recombinant human endostatin (show COL18A1 Antibodies)-gold nanoparticles might normalize vessels by interfering anterior gradient 2-mediated angiogenesis in metastatic colorectal cancer.

  8. AGR2, through interaction with ER-alpha (show ESR1 Antibodies), enhances fulvestrant resistance and IGF-1 (show IGF1 Antibodies)-induced carcinogenesis in breast cancer cells.

  9. AGR2 inhibits TNF-alphainduced Caco-2 cell hyperpermeability by regulating TJ and that this protective mechanism may be promoted by inhibition of NF-kappaB p65-mediated activation of the MLCK/p-MLC signaling pathway.

  10. our study showed the important role of AGR2 in regulating EMT (show ITK Antibodies) of glioblastoma. SDF-1 (show CXCL12 Antibodies) signaling induced the expression of AGR2 to control the progress of EMT (show ITK Antibodies) in the progression of glioblastoma.

Mouse (Murine) Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. AGR2 accelerates skin wound healing through regulation of cell migration.

  2. AGR2 induced in ER-stressed and inflammatory pre-neoplastic pancreas is a potential marker of cancer progenitor cells with an important functional role in PDAC initiation.

  3. impact of AGR2 expression and EGFR (show EGFR Antibodies) signaling on tissue regeneration

  4. EGFR (show EGFR Antibodies)-mediated signaling in NCI-H460 cells is disrupted with reduced AGR2 expression.

  5. AGR2 has both intracellular and extracellular effects in the intestine

  6. Results indicate that DNA methylation (show HELLS Antibodies) within the AGR2 promoter modulates more aggressive cancer cell phenotypes.

  7. It was concluded that: the expression of AGR2 protein was significantly higher in asthmatic mice as compared with their normal counterparts; the expression was obviously related to the expression of Muc5ac protein and IL-13 (show IL13 Antibodies).

  8. Agr2 consequently serves to maintain the balance between proliferating and differentiated epithelial cells.

  9. Agr2 facilitates normal lobuloalveolar development by regulating mammary epithelial cell proliferation; we found no effects on apoptosis in Agr2(-/-) mammary epithelial cells.

  10. Loss of Foxp1 (show FOXP1 Antibodies)/4 in the developing lung and in postnatal secretory epithelium leads to ectopic activation of the goblet cell fate program, in part, through de-repression of the protein disulfide isomerase (show P4HB Antibodies) anterior gradient 2 (Agr2).

AGR2 Antigen Profile

Protein Summary

Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity).

Gene names and symbols associated with AGR2

  • anterior gradient 3 (agr3) antibody
  • anterior gradient 2 homolog (LOC100329406) antibody
  • anterior gradient 2 (AGR2) antibody
  • anterior gradient 2 (Agr2) antibody
  • anterior gradient 2 homolog (Xenopus laevis) (Agr2) antibody
  • anterior gradient 2 homolog (Xenopus laevis) (AGR2) antibody
  • anterior gradient homolog 2 (Xenopus laevis) (AGR2) antibody
  • anterior gradient homolog 2 (Xenopus laevis) (agr2) antibody
  • AG2 antibody
  • agr2 antibody
  • Agr2h antibody
  • bcmp11 antibody
  • Gob-4 antibody
  • HAG-2 antibody
  • hag-3 antibody
  • hag3 antibody
  • mAG-2 antibody
  • MGC89004 antibody
  • PDIA17 antibody
  • wu:fj29g05 antibody
  • XAG-2 antibody
  • zgc:112187 antibody

Protein level used designations for AGR2

anterior gradient 3 , anterior gradient 2 homolog , AG-2 , HPC8 , anterior gradient homolog 2 , anterior gradient protein 2 homolog , protein disulfide isomerase family A, member 17 , secreted cement gland homolog , secreted cement gland protein XAG-2 homolog , protein Gob-4 , anterior gradient 2 homologue

GENE ID SPECIES
448756 Xenopus (Silurana) tropicalis
100329406 Danio rerio
10551 Homo sapiens
23795 Mus musculus
298961 Rattus norvegicus
482333 Canis lupus familiaris
100174601 Pongo abelii
100514482 Sus scrofa
415112 Bos taurus
335616 Danio rerio
420596 Gallus gallus
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