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Anthrax Toxin Receptor 2 Proteins (ANTXR2)

ANTXR2 encodes a receptor for anthrax toxin. Additionally we are shipping ANTXR2 Antibodies (49) and ANTXR2 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANTXR2 71914 Q6DFX2
ANTXR2 118429 P58335
Rat ANTXR2 ANTXR2 305633  
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Top ANTXR2 Proteins at antibodies-online.com

Showing 9 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ANTXR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
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Human , , , ,
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More Proteins for Anthrax Toxin Receptor 2 (ANTXR2) Interaction Partners

Mouse (Murine) Anthrax Toxin Receptor 2 (ANTXR2) interaction partners

  1. blood pressure measured under anesthesia in Antxr2 siRNA-injected mice rose significantly compared with that of the controls, suggesting that ANTXR2 is a causative gene in the human 4q21 GWAS-blood pressure locus.

  2. Silencing CMG2 using targeted siRNAs provided almost complete protection against anthrax lethal toxin-induced cytotoxicity and death in murine and human macrophages.

  3. we have discovered that ANTXR1 (show ANTXR1 Proteins) and ANTXR2 function as positive regulators of MT1-MMP (show MMP14 Proteins) activity.

  4. these results demonstrate that CMG2 is not required for normal mouse embryonic development but is indispensable for murine parturition

  5. This work demonstrates that anthrax toxin uptake through CMG2 and the resulting impairment of myeloid cells are essential to anthrax infection.

  6. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.

  7. Cytoplasmic delivery of lethal factor by anthrax toxin receptor 2 was mediated by cathepsin B (show CTSB Proteins).

  8. because protective antigen binds to CMG2 with much higher affinity than it does to TEM8 (show ANTXR1 Proteins), a lower pH is needed to attenuate CMG2 binding to allow pore formation; toxin can form pores at different points in the endocytic pathway

  9. The mRNA transcripts of both receptors, ANTXR1 (show ANTXR1 Proteins) and ANTXR2 were detected in J774A.1 cells and mouse tissues suggesting that anthrax edema toxin and B. anthracis Sterne spore are involved in the ANTXR mRNA regulation in host cells.

  10. Data show that the lethality of anthrax toxin for mice is mostly mediated by CMG2 and that TEM8 (show ANTXR1 Proteins) plays only a minor role.

Human Anthrax Toxin Receptor 2 (ANTXR2) interaction partners

  1. Anthrax Susceptibility: Human Genetic Polymorphisms Modulating ANTXR2 Expression

  2. miR (show MLXIP Proteins)-124 might induce autophagy to participate in AS by targeting ANTXR2, which might be implicated in pathological process of AS.

  3. The disulfide bond Cys255-Cys279 in the immunoglobulin-like domain of ANTXR2 is required for membrane insertion of anthrax protective antigen pore.

  4. CMG2 glycosylation provides a buffer towards genetic variation by promoting folding of the protein in the ER lumen.

  5. Results show that CMG2 has been shown to be able to regulate the proliferation and tubule formation of endothelial cells, but not the migration.

  6. Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene.

  7. data suggested that cellular cholesterol regulated ANTXR2-dependent activation of MMP-2 via ERK1/2 phosphorylation in neuroglioma U251 cell.

  8. Fused the ANTXR2 ectodomain to the C-terminus of bacterial Trigger Factor (TF), and the fusion protein was overly expressed as a dominant soluble protein in E coli.

  9. Silencing CMG2 using targeted siRNAs provided almost complete protection against anthrax lethal toxin-induced cytotoxicity and death in murine and human macrophages.

  10. Loss of CMG2 expression is associated with breast cancer progression.

ANTXR2 Protein Profile

Protein Summary

This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ANTXR2

  • anthrax toxin receptor 2 (ANTXR2)
  • anthrax toxin receptor 2 (antxr2)
  • anthrax toxin receptor 2 (Antxr2)
  • 2310046B19Rik protein
  • ANTXR2 protein
  • AW561899 protein
  • cI-35 protein
  • CMG-2 protein
  • CMG2 protein
  • DKFZp459A152 protein
  • HFS protein
  • ISH protein
  • JHF protein

Protein level used designations for ANTXR2

anthrax toxin receptor 2 , capillary morphogenesis gene 2 protein , capillary morphogenesis protein 2

GENE ID SPECIES
422580 Gallus gallus
471191 Pan troglodytes
696513 Macaca mulatta
100051770 Equus caballus
100158556 Xenopus (Silurana) tropicalis
100174746 Pongo abelii
100356899 Oryctolagus cuniculus
100582046 Nomascus leucogenys
71914 Mus musculus
118429 Homo sapiens
487821 Canis lupus familiaris
510080 Bos taurus
305633 Rattus norvegicus
100514416 Sus scrofa
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