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Antizyme Inhibitor 1 Proteins (AZIN1)

Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Additionally we are shipping Antizyme Inhibitor 1 Antibodies (19) and Antizyme Inhibitor 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AZIN1 51582 O14977
AZIN1 54375 O35484
AZIN1 58961 Q63764
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Top Antizyme Inhibitor 1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,256.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,256.00
Details
HOST_Sf-9 Cells Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$460.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

AZIN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Antizyme Inhibitor 1 (AZIN1) Interaction Partners

Pig (Porcine) Antizyme Inhibitor 1 (AZIN1) interaction partners

  1. Expression patterns showed that in Lantang pig, the AZ1 gene is differentially expressed in various tissues and displayed higher expression in lung and skeletal muscle

Human Antizyme Inhibitor 1 (AZIN1) interaction partners

  1. AzI1 fulfils an essential regulatory function in polyamine homeostasis and cell proliferation.

  2. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN).

  3. This study also suggests that highly expressed AZI (show OAZ1 Proteins) may be partly responsible for increased ODC (show ODC1 Proteins) activity and cellular transformation.

  4. AZIN1 rs2679757 and TRPM5 (show TRPM5 Proteins) rs886277 are associated with the risk of HBV-related liver cirrhosis in Chinese.

  5. edited form has a stronger affinity to antizyme, and the resultant higher AZIN1 protein stability promotes cell proliferation through the neutralization of antizyme-mediated degradation of ornithine decarboxylase (ODC (show ODC1 Proteins)) and cyclin D1 (show CCND1 Proteins)

  6. minor allelic SNP variant in 12th exon of AZIN1 associated with slower rates of fibrosis progression favors expression of novel splice form, AZIN1 SV2 (show SV2A Proteins), that inhibits expression of fibrogenic genes in hepatic stellate cells.

  7. AZ_95-176 is the minimal AZ peptide that is fully functioning in the binding of ODC (show ODC1 Proteins) and AZI (show OAZ1 Proteins) and inhibition of their function.

  8. SNP rs2679757 in the AZIN1 gene is associated with the risk of HBV-related liver cirrhosis in Chinese patients.

  9. Decreased ornithine decarboxylase (show ODC1 Proteins) is associated with prostate cancer.

Mouse (Murine) Antizyme Inhibitor 1 (AZIN1) interaction partners

  1. The polyamines regulate two novel steps of Azin1 expression, namely the transcription and a particular splicing pattern, both of which may affect the level of mRNA encoding the full-length active Azin1 protein.

  2. miR (show MLXIP Proteins)-433 is an important component of TGF-beta (show TGFB1 Proteins)/Smad3 (show SMAD3 Proteins)-induced renal fibrosis through the induction of a positive feedback loop to amplify TGF-beta (show TGFB1 Proteins)/Smad3 (show SMAD3 Proteins) signaling.

  3. AZI plays an important role in regulating the levels of Ornithine decarboxylase (show ODC1 Proteins), putrescine and spermidine in mice, and is essential for the survival of mice.

  4. differences in the subcellular distribution of AZIN1 and AZIN2 (show ADC Proteins)

  5. The data-driven docking results suggest that both proteins occupy the same binding site on Az1, with Az1 binding within a large groove in antizyme (show OAZ1 Proteins) inhibitor (AzI) and

Antizyme Inhibitor 1 (AZIN1) Protein Profile

Protein Summary

Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with Antizyme Inhibitor 1 Proteins (AZIN1)

  • antizyme inhibitor 1 (AZIN1)
  • antizyme inhibitor 1b (azin1b)
  • antizyme inhibitor 1 (azin1)
  • Antizyme inhibitor 1 (azin1)
  • ornithine decarboxylase antizyme 1a (oaz1a)
  • ornithine decarboxylase antizyme 1 (oaz1)
  • ornithine decarboxylase antizyme 1 (OAZ1)
  • antizyme inhibitor 1 (Azin1)
  • 1700085L02Rik protein
  • AI414949 protein
  • AZ1 protein
  • azi protein
  • azin1 protein
  • AZS protein
  • MGC75770 protein
  • MGC81852 protein
  • oaz protein
  • OAZ1 protein
  • oaz1S protein
  • Oazi protein
  • Oazin protein
  • ODC-Az protein
  • ODC1L protein
  • wu:fj32d12 protein

Protein level used designations for Antizyme Inhibitor 1 Proteins (AZIN1)

antizyme inhibitor 1 , ornithine decarboxylase antizyme inhibitor , Antizyme inhibitor 1 , ODC antizyme , ODC-Az-S , ornithine decarboxylase antizyme 1 , ornithine decarboxylase antizyme 1 long isoform , AZI , ODC antizyme inhibitor

GENE ID SPECIES
464324 Pan troglodytes
475058 Canis lupus familiaris
317764 Danio rerio
420254 Gallus gallus
447408 Xenopus laevis
493320 Xenopus (Silurana) tropicalis
532835 Bos taurus
693581 Macaca mulatta
100023835 Monodelphis domestica
100056267 Equus caballus
100158237 Sus scrofa
100195376 Salmo salar
100398307 Callithrix jacchus
100468174 Ailuropoda melanoleuca
100601793 Nomascus leucogenys
259192 Danio rerio
394475 Xenopus (Silurana) tropicalis
397034 Sus scrofa
455569 Pan troglodytes
476749 Canis lupus familiaris
721477 Macaca mulatta
100190498 Taeniopygia guttata
100196403 Salmo salar
51582 Homo sapiens
54375 Mus musculus
58961 Rattus norvegicus
100173300 Pongo abelii
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