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APOA1 encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. Additionally we are shipping Apolipoprotein A-I Antibodies (528) and Apolipoprotein A-I Kits (88) and many more products for this protein.
Showing 10 out of 106 products:
Human APOA1 Protein expressed in Escherichia coli (E. coli) - ABIN2003220
Soutar, Hawkins, Vigushin, Tennent, Booth, Hutton, Nguyen, Totty, Feest, Hsuan: Apolipoprotein AI mutation Arg-60 causes autosomal dominant amyloidosis. in Proceedings of the National Academy of Sciences of the United States of America 1992
Show all 4 references for ABIN2003220
Human APOA1 Protein expressed in Escherichia coli (E. coli) - ABIN413012
Barlic, Zhu, Murphy: Atherogenic lipids induce high-density lipoprotein uptake and cholesterol efflux in human macrophages by up-regulating transmembrane chemokine CXCL16 without engaging CXCL16-dependent cell adhesion. in Journal of immunology (Baltimore, Md. : 1950) 2009
Show all 3 references for ABIN413012
Mouse (Murine) APOA1 Protein expressed in Human Cells - ABIN2008404
Eggerman, Hoeg, Meng, Tombragel, Bojanovski, Brewer: Differential tissue-specific expression of human apoA-I and apoA-II. in Journal of lipid research 1991
Show all 3 references for ABIN2008404
Human APOA1 Protein expressed in Escherichia coli (E. coli) - ABIN667126
Khadem-Ansari, Rasmi, Rahimi-Pour, Jafarzadeh: The association between serum apolipoprotein A-I and apolipoprotein B and the severity of angiographical coronary artery disease. in Singapore medical journal 2009
Show all 2 references for ABIN667126
APOA1 SNPs (rs670, rs5069, and rs2070665) are not associated with dyslipidemia in the Kazakh population of China.
the data described the region around residue 217 in the C-terminal domain of apoA-I as the most sensitive reporter of the crowding-induced self-association of apoA-I. The implications of this behavior to in vivo functionality are discussed.
ApoA1 is increasingly expressed and secreted as a delayed response to neuronal injury, and this is a self-protecting mechanism of the injured system.
A novel APOA1 mutation in hereditary apolipoprotein A-I amyloidosis
The genotype frequency of APOA1 (rs5069, rs670) in a cohort of patients with CAA (show TSHZ1 Proteins)-associated intracerebral hemorrhage was compared with hypertension-associated ICH (show COL4a2 Proteins), Alzheimer disease, and controls. The APOA1 genotypes were not different among groups. apoA1 may act as a physiological transporter of Abeta (show APP Proteins)(1-40).
RVX-208 raises ApoA-I/HDL (show HSD11B1 Proteins) and represses pro-inflammatory, pro-atherosclerotic and pro-thrombotic pathways that can contribute to cardiovascular disease risk.
Epigenetic silencing of ApoA1 gene expression by CpG island DNA hypermethylation induced by Hepatitis B virus.
protein(s) in the homogenate interact with HDL (show HSD11B1 Proteins) protein(s), leading to release of Apo (show C9orf3 Proteins) A1 from the HDL (show HSD11B1 Proteins) particle, a process that was associated with an increase in HDL (show HSD11B1 Proteins) diameter and with impaired HDL (show HSD11B1 Proteins) anti-oxidant activity.
Data indicate that serum apolipoproteins ApoB (show APOB Proteins), ApoA-1 and ApoB (show APOB Proteins)/A-1 ratio levels are independently associated with coronary heart disease (CHD (show CHDH Proteins)) risk in Korean men.
Expression of ApoA-1 and ApoC-III (show APOC3 Proteins) in SCLC was significantly different, compared with that in NSCLC and normal lung tissues, and was correlated with recurrence of SCLC.
results demonstrate that double deletion of Apoe (show APOE Proteins) and Apoa1 ameliorated the amyloid pathology.
study suggests that apolipoprotein a1 can alleviate obesity related metabolic disease by inducing AMPK (show PRKAA1 Proteins) dependent mitochondrial biogenesis.
ApoA-I can attenuate lymphocyte activation and autoimmunity in Lupus independently of cholesterol transport, through oxidized fatty acid peroxisome proliferator-activated receptor gamma (show PPARG Proteins) ligands, and it can reduce renal inflammation in glomerulonephritis.
KLF14 (show SP6 Proteins) regulates plasma HDL (show HSD11B1 Proteins)-C levels and cholesterol efflux capacity by modulating hepatic ApoA-I production.
Akt (show AKT1 Proteins), through its downstream targets, mTORC1 and hence autophagy, negatively regulates cholesterol efflux to apoA-I.
macrophage apoAI expression protects against atherosclerosis and dermatitis by reducing cholesterol accumulation and regulating CD4 (show CD4 Proteins)(+) T-cell levels, without affecting serum HDL (show HSD11B1 Proteins) or tissue macrophage levels.
HDL (show HSD11B1 Proteins) from apoA1 transgenic mice expressing the 4WF isoform is resistant to oxidative loss of function.
ApoA1 levels were not associated with AngII-induced abdominal aortic aneurysms in mice.
decreased ApoAI synthesis might be accounted for the lower plasma HDL (show HSD11B1 Proteins) level in ApoCIII (show APOC3 Proteins) transgenic mice
MMP-8 (show MMP8 Proteins)-deficient mice had significantly lower serum triglyceride (TG) levels (P = 0.003) and larger HDL (show HSD11B1 Proteins) particles compared with wild-type (WT) mice. However, no differences were observed in the apoA-I levels.
Alterations in the Apo A (show APOA Proteins)-I pattern is a good indicator of the presence and severity of infectious diseases in the pig.Lower overall amounts of Apo A (show APOA Proteins)-I were observed in Salmonella typhimurium and Escherichia coli infections.
down-regulation of apolipoprotein A-I and A-IV messages in the liver may be mediated by interleukin 6 (show IL6 Proteins) and tumor necrosis factor-alpha (show TNF Proteins)
This study showed that apoA-I exerted protective effects against fatty liver disease in rabbits induced by a high-fat diet, possibly through its antioxidant actions.
The molar ratio ApoE (show APOE Proteins)/ApoA-I is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.
Binding of apoA-I to ectopic F(0)F(1) ATPase (show ATP5E Proteins) triggers the generation of ADP, which via activation of the purinergic receptor P2Y (show P2RY1 Proteins)(12) stimulates the uptake and transport of HDL (show HSD11B1 Proteins) and initially lipid-free apoA-I by endothelial cells.
the model of a two-step process for the transendothelial transport of apoA-I in which apoA-I is initially lipidated by ABCA1 (show ABCA1 Proteins) and then further processed by ABCA1 (show ABCA1 Proteins)-independent mechanisms.
insulin (show INS Proteins) secretion and tissue rejuvenation activities of WT-reconstituted high-density lipoproteins were nearly depleted by fructosylation, but V156K-rHDL did not lose its beneficial activity.
The NABB system using engineered zebrafish apo A-I is a native-like membrane mimetic system for G-protein-coupled receptors.
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
, apolipoprotein A-I-like
, apolipoprotein A-I preproprotein
, apolipoprotein A1
, apolipoprotein A-1
, preproapolipoprotein A-I
, Apolipoprotein A1
, Apolipoprotein A-I