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Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. Additionally we are shipping APOA4 Antibodies (183) and APOA4 Kits (65) and many more products for this protein.
Showing 10 out of 28 products:
Apolipoprotein L1 (show APOL1 Proteins) and apolipoprotein A-IV and their association with kidney function
APOA-IV glycation is associated with coronary artery disease severity in patients with Type 2 Diabetes Mellitus.
These findings indicate that LZIP (show CREB3 Proteins) is a novel modulator of APOA4 expression and hepatic lipid metabolism.
Study discovered novel and independent associations of prediabetes and related traits with MASP1 (show MASP1 Proteins), and some evidence for associations with THBS1 (show THBS1 Proteins), GPLD1 (show GPLD1 Proteins) and ApoA-IV, suggesting a role for these proteins in the pathophysiology of type 2 diabetes.
Analyses of SNP-scores indicate potential causal effects of kidney function and by lesser extent triglycerides on apoA-IV concentrations.
Low levels of APOA1 (show APOA1 Proteins), APOC3 (show APOC3 Proteins), and APOA4 are associated with risk of Alzheimer disease.
Single nucleotide polymorphisms (Rs7396835) of APOA4 protein did not increase the risk of CHD (show CHDH Proteins) in the Chinese population.
ApoA-IV colocalizes with NR4A1 (show NR4A1 Proteins), which suppresses G6Pase (show G6PC Proteins) and PEPCK (show PEPCK Proteins) gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.
the present findings reveal that High-altitude polycythemia -induced gastric mucosal lesion inspires the protection responses by up-regulating APOA4 and APOC3 (show APOC3 Proteins), and down-regulating GIF (show GIF Proteins).
analysis of methylation patterns of the APOA1 (show APOA1 Proteins)/C3/A4/A5 cluster that may be directly involved in the transcriptional regulation of this cluster, especially in liver
zebrafish ApoA-IV performs a conserved role to that in rat in the regulation of food intake by transiently overexpressing ApoA (show APOA1 Proteins)-IVb.
MTTP (show MTTP Proteins) is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption.
down-regulation of apolipoprotein A-I (show APOA1 Proteins) and A-IV messages in the liver may be mediated by interleukin 6 (show IL6 Proteins) and tumor necrosis factor-alpha (show TNF Proteins)
Hepatocyte nuclear factor 4 alpha (HNF-4 alpha (show HNF4A Proteins))induces apoliprotein IV gene in response to dietary lipids in the intestine.
APOA4 genes with SNPs
Upregulation of the intestinal apolipoprotein APOA-IV in horses with chronic laminitis was confirmed by western blot.[APOA-IV]
This study uncovers an anti-sense lncRNA (APOA4-AS), which is co-expressed with APOA4, and concordantly and specifically regulates APOA4 expression both in vitro and in vivo with the involvement of HuR (show ELAVL1 Proteins).
Our findings may throw light on the function of ApoA4 in inflammatory responses and acute-phase reactions, as well as the development of SERPINA3 (show SERPINA3 Proteins) relative diseases.
Very Low Density Lipoprotein (VLDL) assembly and CREBH (show CREB3L3 Proteins) activation play key roles in the response to hepatic steatosis by up-regulating apoA-IV and promoting assembly and secretion of larger, more triglyceride - enriched VLDL particles.
It was suggested that increased ileal GPR119 (show GPR119 Proteins) is a potential mechanism by which GLP-1 (show GCG Proteins) secretion is enhanced in apoA-IV-/- mice.
these data suggest that apoA-IV is not necessary for the metabolic improvements shown with VSG, but also suggest an interesting role for apoA-IV in regulating macronutrient preference and hepatic triglyceride levels.
These results reveal ApoA-IV as a novel follicle-associated epithelium-specific marker especially in the upper small intestine of adult mice.
transcriptional regulation of apolipoprotein A-IV by the transcription factor CREBH (show CREB3L3 Proteins)
apoA-IV inhibits hepatic gluconeogenesis by decreasing Glc-6-Pase (show G6PC Proteins) and PEPCK (show PEPCK Proteins) gene expression through NR1D1 (show NR1D1 Proteins).
Hepatic steatosis in mice induces hepatic apoA-IV expression, which in turn promotes lipoprotein particle expansion and reduces hepatic lipid burden without increasing the number of secreted atherogenic apoB (show APOB Proteins)-containing lipoprotein particles.
Data indicate that plasma lipids, lipid absorption, and microsomal triglyceride transfer protein (MTP (show MTTP Proteins)), FoxO1 (show FOXO1 Proteins), and FoxA2 (show FOXA2 Proteins) levels are lower at night and at mealtime in apoAIV-/- mice.
Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.
, apolipoprotein A4
, Apo A-IV
, apolipoprotein A-IV
, apolipoprotein A-IV-like