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Apolipoprotein B Proteins (APOB)

APOB product is the main apolipoprotein of chylomicrons and low density lipoproteins. Additionally we are shipping APOB Antibodies (354) and APOB Kits (144) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOB 338 P04114
APOB 54225 Q7TMA5
APOB 238055  
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Top APOB Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 9 to 11 Days
$330.00
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Human Human Un-conjugated 500 μg Log in to see 2 to 3 Days
$252.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$492.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,210.17
Details
HOST_Human Human Un-conjugated   500 μg Log in to see 7 to 9 Days
$210.36
Details
HOST_Human Human Un-conjugated   0.5 mg Log in to see 3 to 4 Days
$225.87
Details

APOB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Apolipoprotein B (APOB) Interaction Partners

Human Apolipoprotein B (APOB) interaction partners

  1. 10 association studies for Han Chinese, with 1195 CHD patients and 1178 healthy subjects, we found that XbaI (rs693) polymorphisms in APOB were statistically significantly associated with Coronary Heart Disease in Han Chinese population

  2. We observed a significant interaction between Ins (show INS Proteins)/Del ApoB genotype and dietary omega-3 PUFA intake with respect to BMI, WC, and obesity risk in both unadjusted (P = 0.007, P = 0.001, and P = 0.021, respectively) and adjusted (P = 0.007, P = 0.04, and P = 0.002, respectively) samples in NIDDM patients.

  3. Compared with healthy controls, preeclamptic patients had significantly lower Apo A (show APOA Proteins)-1 levels (167.07mg/dl+/-14.61mg/dl vs. 244.37mg/dl+/-20.84mg/dl, p<0.001), higher Apo B-100/Apo A (show APOA Proteins)-1 ratio (0.63+/-0.07 vs. 0.42+/-0.05, p<0.001), but similar Apo B-100 levels (104.84mg/dl+/-7.05mg/dl vs. 102.39mg/dl+/-8.08mg/dl, p=0.118).

  4. Higher level of some risk factors like PAB values, apoB/A1 ratio concentration, and lipid profiles is able to involve in the prognostic pathological consequences in patients with beta-thalassemia major. Even so, they contribute toward the gradual development of CVD.

  5. Multiple novel LDLR (show LDLR Proteins) and ApoB mutations have been identified in a-United Kingdom-based cohort with familial hypercholesterolemia.

  6. Data suggest that LDL-C/apoB ratio (ratio of plasma level of total cholesterol to plasma level of apolipoprotein B) is an important biomarker in overall evaluation of atherogenicity in obese, overweight, and normal-weight men; this study of qualitative changes in lipid/lipoprotein profile for early diagnosis of dyslipidemias leading to atherosclerosis was conducted in Russia.

  7. Mutations in APOB is associated with hypobetalipoproteinemia.

  8. LDLR (show LDLR Proteins) A(+)A(+) genotype, ApoB X(+) allele and ApoE (show APOE Proteins) E4 allele increased the risk of premature coronary artery disease by 1.8, 2.1 and 12.1 respectively.

  9. C7673T polymorphism in apoB gene is significantly associated with increased ischemic stroke risk in the Chinese population.

  10. Apo-B correlation with both LDL-C and non-HDL-C is reduced in individuals with high TG levels and in particular for those with diabetes or MetS.

Cow (Bovine) Apolipoprotein B (APOB) interaction partners

  1. Cholesterol deficiency results from a 1.3kbp insertion of an endogenous retrovirus (ERV2-1-LTR_BT) into exon 5 of the APOB gene at BTA11:77,959kb. The insertion is flanked by 6bp target site duplications as described for insertions mediated by retroviral integrases.

  2. A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle

  3. Nonesterified fatty acids significantly inhibit the expression of ApoB100, ApoE (show APOE Proteins), MTP (show MTTP Proteins), and LDLR (show LDLR Proteins), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  4. after calving the apolipoprotein B(100) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (show MTTP Proteins)) and apolipoprotein E (show APOE Proteins) messenger RNA abundance were higher in the liver.

Mouse (Murine) Apolipoprotein B (APOB) interaction partners

  1. We carried out our experiment in mice deficient in the low density lipoprotein (LDL) receptor (show LDLR Proteins) and expressing only ApoB100 molecule (ApoB - LDLr (show LDLR Proteins)) where the development of atherosclerosis is known to closely mimic human atherosclerosis

  2. The effect of hypercholesterolemia induced immune response and inflammation on progression of atherosclerosis in ApoB(tm25gy) LDLr (show LDLR Proteins)(tm1Her) mice, expressing only ApoB100 and deficient in the low density lipoprotein receptor (show LDLR Proteins).

  3. ApoB-containing lipoproteins contribute to augmentation of AngII-induced abdominal aortic aneurysms in male mice.

  4. Immunization with human apolipoprotein B100 (ApoB) resulted in four-fold increased accumulation of effector T cells in ApoB-containing matrigel

  5. PCSK9 (show PCSK9 Proteins) markedly increases intestinal triglyceride-rich apoB production through mechanisms mediated in part by transcriptional effects on apoB.

  6. Mice that produce apoB100 in the RPE (show RPE Proteins) and liver secrete lipoproteins into Bruch's membrane, but not to the extent that distinct features of AMD (show AMD1 Proteins) develop

  7. The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor-deficient apolipoprotein B-100-only mice, with IGF-II overexpression.

  8. Our data establish the role of APOB gene in severe gut (show GUSB Proteins) dysmotility.

  9. Cardiac lipotoxicity may originate from direct inhibition of myocardial ApoB lipoprotein and subsequent decreased lipid export, caused by supraphysiological levels of catecholamines.

  10. ApoB-100 transgenic animals present i) elevated serum and cerebral levels of triglycerides and ApoB-100, ii) increased cerebral tau phosphorylation at phosphosites Ser (show SIGLEC1 Proteins)(199), Ser (show SIGLEC1 Proteins)(199/202), Ser (show SIGLEC1 Proteins)(396) and Ser (show SIGLEC1 Proteins)(404).

Pig (Porcine) Apolipoprotein B (APOB) interaction partners

  1. found association between genotypes for LDLR (show LDLR Proteins) and APOB polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

APOB Protein Profile

Protein Summary

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Gene names and symbols associated with Apolipoprotein B Proteins (APOB)

  • apolipoprotein B (APOB)
  • apolipoprotein B (Apob)
  • apolipoprotein B (including Ag(x) antigen) (APOB)
  • Ac1-060 protein
  • AI315052 protein
  • ApoB(100) protein
  • apob-48 protein
  • Apo B-100 protein
  • apob-100 protein
  • FLDB protein
  • LDLCQ4 protein

Protein level used designations for Apolipoprotein B Proteins (APOB)

apo B-100 , apoB-100 , apoB-48 , apolipoprotein B (including Ag(x) antigen) , apolipoprotein B-100 , apolipoprotein B48 , mutant Apo B 100 , apolipoprotein B PI , apolipoprotein B-48 , apolipoprotein B

GENE ID SPECIES
338 Homo sapiens
54225 Rattus norvegicus
494004 Bos taurus
100725937 Cavia porcellus
238055 Mus musculus
100523371 Sus scrofa
100009101 Oryctolagus cuniculus
475680 Canis lupus familiaris
101107590 Ovis aries
396535 Gallus gallus
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