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APOBEC3G is a member of the cytidine deaminase gene family. Additionally we are shipping APOBEC3G Antibodies (174) and APOBEC3G Proteins (9) and many more products for this protein.
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thousands of mutation clusters introduced along primate evolution which exhibit features that strongly fit the known patterns of APOBEC3G mutagenesis. These results suggest that APOBEC3G-induced mutations have contributed to the evolution of all genomes
the effect of APOBEC3G over-expression upon AATF (show AATF ELISA Kits) gene expression, was examined.
The results disclosed no association between the single nucleotide polymorphisms of APOBEC3G and susceptibility to HIV-1, or effects of these polymorphisms on the CD4 (show CD4 ELISA Kits)(+) T cell count or clinical phase of disease.
Findings support a role for APOBEC3G/F proteins in the generation of plasma drug-resistant minority human immunodeficiency virus type 1 variants (DRMVs). However, this role seems to be limited to a small subset of mutations and does not explain most of the DRMVs evaluated.
STAT3 (show STAT3 ELISA Kits) plays an important role in IFN-induced A3G production, and HBsAg may correlated with poor response to IFN treatment
Data show that restriction factor APOBEC3G (A3G) is susceptible to degradation by the HIV-1 Vif (show BTG1 ELISA Kits) protein, whereas restriction factor APOBEC3B (show APOBEC3B ELISA Kits) (A3B (show SGCB ELISA Kits)) is resistant to Vif (show BTG1 ELISA Kits).
This study demonstrates an association of rs6001417, rs8177832, and rs35228531 of APOBEC3G with HIV-1 infection in a population from Burkina Faso.
Results were consistent with Pokeweed antiviral protein activity inhibiting translation of Vif (show BTG1 ELISA Kits), which in turn reduces the effect of Vif (show BTG1 ELISA Kits) to inactivate the host restriction factor APOBEC3G.
USF1 (show USF1 ELISA Kits) gene can take part in basal transcription regulation of the human A3G gene in hepatocyte, and the identified E-box represented a binding site for the USF1 (show USF1 ELISA Kits).
Incomplete APOBEC3G/F neutralization by a single Vif (show BTG1 ELISA Kits) amino acid substitution.
APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host.
The arginine at position 14 of the SIV Vif (show BTG1 ELISA Kits) is a critical residue for virus restriction by rhA3D, rhA3G and rhA3H.
APOBEC3F/G-specific responses in HIV-1-infected rhesus macaques are CD8 (show CD8A ELISA Kits)+ T cell mediated.
Vif (show BTG1 ELISA Kits) proteins of human and simian immunodeficiency viruses require cellular CBFbeta (show CBFB ELISA Kits) to degrade APOBEC3G.
simian immunodeficiency virus (SIV) Vif (show BTG1 ELISA Kits) binds to and requires CBF-beta (show CBFB ELISA Kits) to degrade rhesus macaque APOBEC3G
Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.
APOBEC3 proteins restrict xenotropic murine leukemia virus-related virus infections in a Macaca mulatta model.
Alteration of the conserved sequence at positions 14 to 17 from DRMR to SERQ, which is the sequence in AGM (show IGFBP7 ELISA Kits) Vif (show BTG1 ELISA Kits), caused HIV-1 Vif (show BTG1 ELISA Kits) to functionally interact with rhAPOBEC3G and agmAPOBEC3G
Upregulation of APOBEC3G may restrict spread of SIV in the brain and thus limit brain damage during lentiviral infection
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
DNA dC->dU-editing enzyme APOBEC-3G
, deoxycytidine deaminase
, APOBEC-related cytidine deaminase
, APOBEC-related protein 9
, DNA dC->dU editing enzyme
, apolipoprotein B editing enzyme catalytic polypeptide-like 3G
, apolipoprotein B mRNA editing enzyme cytidine deaminase
, phorbolin-like protein MDS019
, apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G
, apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G