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Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H) ELISA Kits

APOBEC3H encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. Additionally we are shipping APOBEC3H Antibodies (7) and APOBEC3H Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human APOBEC3H APOBEC3H 164668 Q6NTF7
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More ELISA Kits for APOBEC3H Interaction Partners

Human Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H) interaction partners

  1. The eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population

  2. APOBEC3H haplotype II was able to processively deaminate multiple cytosines in a single enzyme-substrate encounter by using sliding, jumping, and intersegmental transfer movements.

  3. The existence and persistence of both types of HIV-1 Vif (show BTG1 ELISA Kits) variant suggests the importance of APOBEC3H suppression and cell cycle regulation for HIV-1's survival in vivo.

  4. Importantly, APOBEC3H appears to use both deaminase-dependent and -independent mechanisms to target reverse transcription and restrict HIV-1 replication.

  5. stable APOBEC3H haplotypes present as in vivo barriers to HIV-1 replication, that Vif (show BTG1 ELISA Kits) is capable of adapting to these restrictive pressures, and that an evolutionary equilibrium has yet to be reached.

  6. A3H with low anti-HIV-1 activity, APOBEC3H-hapC, is associated with the susceptibility to HIV-1 infection, whereas the A3H producing a stable protein, A3H-hapB, may confer a low risk of disease progression to AIDS.

  7. APOBEC3 deaminases upregulated by IFN-beta (show IFNB1 ELISA Kits) induce E2 hypermutation of HPV16 in cervical keratinocytes.

  8. Taken together, these data validate APOBEC3H expressed at endogenous levels as a bona fide HIV-1 restriction factor.

  9. A3H-hapII is resistant to NL4-3 Vif (show BTG1 ELISA Kits) while it is efficiently degraded by LAI Vif (show BTG1 ELISA Kits).

  10. Amino acid changes within APOBEC3H can give rise to variants that are highly diverse in anti-viral activities and cellular localizations.

Rhesus Monkey Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H) interaction partners

  1. The arginine at position 14 of the SIV Vif (show BTG1 ELISA Kits) is a critical residue for virus restriction by rhA3D, rhA3G and rhA3H.

APOBEC3H Antigen Profile

Antigen Summary

This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with APOBEC3H

  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H (APOBEC3H) antibody
  • A3H antibody
  • APOBEC3A antibody
  • ARP10 antibody

Protein level used designations for APOBEC3H

APOBEC-related protein 10 , ARP-10 , DNA dC->dU-editing enzyme APOBEC-3H , apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H

GENE ID SPECIES
100458762 Pongo abelii
164668 Homo sapiens
723811 Macaca mulatta
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