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Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H Proteins (APOBEC3H)

APOBEC3H encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. Additionally we are shipping APOBEC3H Antibodies (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOBEC3H 164668 Q6NTF7
APOBEC3H    
APOBEC3H    
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Top APOBEC3H Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,517.17
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
$2,520.83
Details

APOBEC3H Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Macaca mulatta

Pongo pygmaeus

More Proteins for Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H) Interaction Partners

Human Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H) interaction partners

  1. The eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population

  2. APOBEC3H haplotype II was able to processively deaminate multiple cytosines in a single enzyme-substrate encounter by using sliding, jumping, and intersegmental transfer movements.

  3. The existence and persistence of both types of HIV-1 Vif (show BTG1 Proteins) variant suggests the importance of APOBEC3H suppression and cell cycle regulation for HIV-1's survival in vivo.

  4. Importantly, APOBEC3H appears to use both deaminase-dependent and -independent mechanisms to target reverse transcription and restrict HIV-1 replication.

  5. stable APOBEC3H haplotypes present as in vivo barriers to HIV-1 replication, that Vif (show BTG1 Proteins) is capable of adapting to these restrictive pressures, and that an evolutionary equilibrium has yet to be reached.

  6. A3H with low anti-HIV-1 activity, APOBEC3H-hapC, is associated with the susceptibility to HIV-1 infection, whereas the A3H producing a stable protein, A3H-hapB, may confer a low risk of disease progression to AIDS.

  7. APOBEC3 (show APOBEC3F Proteins) deaminases upregulated by IFN-beta (show IFNB1 Proteins) induce E2 hypermutation of HPV16 in cervical keratinocytes.

  8. Taken together, these data validate APOBEC3H expressed at endogenous levels as a bona fide HIV-1 restriction factor.

  9. A3H-hapII is resistant to NL4-3 Vif (show BTG1 Proteins) while it is efficiently degraded by LAI Vif (show BTG1 Proteins).

  10. Amino acid changes within APOBEC3H can give rise to variants that are highly diverse in anti-viral activities and cellular localizations.

Rhesus Monkey Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H) interaction partners

  1. The arginine at position 14 of the SIV Vif (show BTG1 Proteins) is a critical residue for virus restriction by rhA3D, rhA3G and rhA3H.

APOBEC3H Protein Profile

Protein Summary

This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with APOBEC3H

  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H (APOBEC3H)
  • A3H protein
  • APOBEC3A protein
  • ARP10 protein

Protein level used designations for APOBEC3H

APOBEC-related protein 10 , ARP-10 , DNA dC->dU-editing enzyme APOBEC-3H , apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H

GENE ID SPECIES
100458762 Pongo abelii
164668 Homo sapiens
723811 Macaca mulatta
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