Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
APOBEC3H encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. Additionally we are shipping APOBEC3H Antibodies (9) and APOBEC3H Proteins (3) and many more products for this protein.
Stable variants of APOBEC3H impose selective pressure on HIV-1.
The deamination activity of these APOBEC3H variants correlates well with their reported anti-HIV activity for the different haplotypes, suggesting that deaminase activity may be an important factor in determining their respective anti-HIV activities.
These results indicate that APOBEC3 proteins can be copackaged and can comutate the same genomes, and can cooperate to inhibit HIV replication.
There are 10 APOBEC3H residues required for the HIV-1 Vif (show BTG1 ELISA Kits) susceptibility and Vif (show BTG1 ELISA Kits) binding.
The eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population
APOBEC3H haplotype II was able to processively deaminate multiple cytosines in a single enzyme-substrate encounter by using sliding, jumping, and intersegmental transfer movements.
The existence and persistence of both types of HIV-1 Vif (show BTG1 ELISA Kits) variant suggests the importance of APOBEC3H suppression and cell cycle regulation for HIV-1's survival in vivo.
Importantly, APOBEC3H appears to use both deaminase-dependent and -independent mechanisms to target reverse transcription and restrict HIV-1 replication.
stable APOBEC3H haplotypes present as in vivo barriers to HIV-1 replication, that Vif (show BTG1 ELISA Kits) is capable of adapting to these restrictive pressures, and that an evolutionary equilibrium has yet to be reached.
A3H with low anti-HIV-1 activity, APOBEC3H-hapC, is associated with the susceptibility to HIV-1 infection, whereas the A3H producing a stable protein, A3H-hapB, may confer a low risk of disease progression to AIDS.
The arginine at position 14 of the SIV Vif (show BTG1 ELISA Kits) is a critical residue for virus restriction by rhA3D, rhA3G and rhA3H.
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.
APOBEC-related protein 10
, DNA dC->dU-editing enzyme APOBEC-3H
, apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H