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Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. Additionally we are shipping APOBR Antibodies (67) and many more products for this protein.
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The obesity risk alleles of non-synonymous SNPs at SH2B1 (show SH2B1 Proteins) and APOB48R have no strong effect on weight loss-related phenotypes in overweight children after a 1-year lifestyle intervention.
These findings suggest that APOB48R represents a molecular target of postprandial lipoproteins via PPAR-dependent pathways in human monocytes and macrophages and advance an important link between postprandial metabolism of dietary fats and atherogenesis.
investigation of apoB48R gene transcription in circulating monocytes: increase in apoB48R gene transcription following high-fat meal
Atherogenic remnant lipoproteins induced macrophage foam cell formation via apoB48R, indicating a potential role of apoB48R in atherosclerosis.
Nucleotide variations in the apolipoprotein B48 receptor gene is associated with hypercholesterolemia
Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis.
apolipoprotein B48 receptor
, apolipoprotein B-100 receptor
, apolipoprotein B-48 receptor
, apolipoprotein B100 receptor