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APOC2 encodes a lipid-binding protein belonging to the apolipoprotein gene family. Additionally we are shipping Apolipoprotein C-II Antibodies (109) and Apolipoprotein C-II Proteins (26) and many more products for this protein.
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Mouse (Murine) Apolipoprotein C-II ELISA Kit for Sandwich ELISA - ABIN810823
Cai, Ying, Song, Wang, Xu, Vanhoutte, Tang: Mice lacking prostaglandin E receptor subtype 4 manifest disrupted lipid metabolism attributable to impaired triglyceride clearance. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015
Rat (Rattus) Apolipoprotein C-II ELISA Kit for Sandwich ELISA - ABIN432455
Sucajtys-Szulc, Szolkiewicz, Swierczynski, Rutkowski: Up-regulation of Hnf1α gene expression in the liver of rats with experimentally induced chronic renal failure - A possible link between circulating PCSK9 and triacylglycerol concentrations. in Atherosclerosis 2016
the apoc2 mutant zebrafish is a robust and versatile animal model to study hypertriglyceridemia.
The results highlight the importance of charge-pair interactions within the apoC-II fibril core
Conformational rearrangement of apoC-II at lipoprotein surfaces promotes interaction with LPL (show LCP1 ELISA Kits).
Large deletion in APOC2 caused by Alu-Alu homologous recombination is associated with with apolipoprotein C-II deficiency.
No APOC2 mutations were identified in a cohort of patients with diabetic lipemia.
Six apolipoproteins (APOA1 (show APOA1 ELISA Kits), APOA2 (show APOA2 ELISA Kits), APOB (show APOB ELISA Kits), APOC2, APOC3 (show APOC3 ELISA Kits), and APOE (show APOE ELISA Kits)) were able to differentiate bladder cancer from hernia. SAA4 (show SAA4 ELISA Kits) was significantly increased in bladder cancer subgroups, whereas ProEGF was significantly decreased in bladder cancer subgroups.
STAT1 (show STAT1 ELISA Kits) bound on multienhancer 2 cooperates with RXRalpha (show RXRA ELISA Kits) located on apoCII promoter and upregulates apoCII expression only in macrophages.
Mutations in GPIHBP1 (show GPIHBP1 ELISA Kits) are rare but the associated clinical phenotype of hypertriglyceridaemia is severe
These results support a predictive change in the ratio of plasma ApoCIII (show APOC3 ELISA Kits) to ApoCII in pregnancies complicated by severe preeclampsia.
Substoichiometric concentrations of cyc (show CYCS ELISA Kits)[60-70] significantly delayed fibril formation by the fibrillogenic, linear peptides apoC-II[60-70] and apoC-II[56-76].
Activation of apoC-II fibrils by submicellar lipid (NBD-lyso-12-phosphocholine) is catalytic with release of monomer- and tetramer-bound lipid accompanying fibril elongation and growth.
A novel mouse model of apoC-II deficiency was created with an apoC-II peptide that reverses the hypertriglyceridemia.
Data show that apoC-II and LPL (show LPL ELISA Kits) mRNAs correlate temporally and geographically with surfactant lipid synthesis in preparation for birth and suggest that fatty acid recruitment from the circulation by apoC-II-activated LPL (show LPL ELISA Kits) is modulated by apoC-II secretion.
TR4 (show NR2C2 ELISA Kits) can also regulate apolipoprotein E (show APOE ELISA Kits), C-I, and C-II gene expression via the TR4 (show NR2C2 ELISA Kits) response element within the hepatic control region
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.
, apolipoprotein C2