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APOD encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. Additionally we are shipping Apolipoprotein D Kits (44) and Apolipoprotein D Proteins (25) and many more products for this protein.
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Human Polyclonal Apolipoprotein D Primary Antibody for WB - ABIN652333
Do Carmo, Jacomy, Talbot, Rassart: Neuroprotective effect of apolipoprotein D against human coronavirus OC43-induced encephalitis in mice. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
apoD protein levels are variable across different brain regions.
The data suggest that the presence of Apo D in the nucleus, which some authors related with a specific transport, is a consequence of structural and functional alterations during oxidative stress
hepatic steatosis observed in apoD Tg mice is a consequence of increased PPARgamma (show PPARG Antibodies) transcriptional activity by AA leading to increased fatty acid uptake by the liver
The SNP rs7659 within the APOD gene might be related to risk and severity of ischemic stroke in patients.
apoD mediates binding of high density lipoprotein to low density lipoprotein and to growing T24 carcinomas, thereby highlighting the importance of apoD in lipid metabolism.
The internalization of apoD is mediated by basigin.
ApoE (show APOE Antibodies) is located in the nucleus and on the ApoD promoter in human hepatic and glioblastoma cells lines.
Rs7659, 3' UTR (show UTS2R Antibodies) polymorphism of the APOD gene was associated with early onset Alzheimer disease in APOEepsilon4 (-) subgroup. Our results suggest that the variation of the APOD gene modifies the risk for Alzheimer disease.
ApoD mRNA expression is seen in whole endometrium, stromal and epithelial cells in the secretory phase, as well as after hormonal stimulation in vitro.
We propose that strong brainstem expression of Apo D throughout adult life contributes to resistance against neurodegenerative disease and age-related degeneration, possibly by preventing oxidative stress and ensuing lipid peroxidation.
apoD may be part of an intrinsic cardioprotective system, possibly as a consequence of its antioxidation activity.
Changes in hypothalamus of ApoD(-/-) mice may indicate potential role of ApoD in regulation of endocrine functions of somatostatin (show SST Antibodies) in a receptor-dependent manner.
Abeta25-35 induces neuroprotective ApoD expression in hippocampal cells in response to stress-induced growth arrest.
The findings underscore the importance of ApoD in the regulation of plasma insulin (show INS Antibodies) levels and triglyceride metabolism, suggesting that ApoD plays an important role in the pathogenesis of dyslipidemia.
The data of this study supported that ApoD contributes to the endurance of astrocytes and decreases their reactivity level in vitro and in vivo
Scanning cytometry revealed PACAP (show ADCYAP1 Antibodies)/ApoD induced low density lipoprotein receptors (LDLR (show LDLR Antibodies)) and ApoE receptor 2 (apoER2 (show LRP8 Antibodies)) in NF200 (show NEFH Antibodies)-positive cells.
mRNA and protein expression profiles reveal that ApoD is functionally connected in an age-dependent manner to specific molecular programs triggered by injury.
Apolipoprotein D plays a significant role in lipid metabolism.
This study concluded that glutamatergic pathways seem to be particularly affected in ApoD(-/-) mice.
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.
, Apolipoprotein D
, apolipoprotein D-like