Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Antibodies (119) and APOL1 Proteins (5) and many more products for this protein.
Showing 10 out of 25 products:
Human APOL1 ELISA Kit for Sandwich ELISA - ABIN419395
Van Vinh Chau, Buu Chau, Desquesnes, Herder, Phu Huong Lan, Campbell, Van Cuong, Yimming, Chalermwong, Jittapalapong, Ramon Franco, Tri Tue, Rabaa, Carrique-Mas, Pham Thi Thanh, Tran Vu Thieu, Berto et al.: A Clinical and Epidemiological Investigation of the First Reported Human Infection With the Zoonotic Parasite Trypanosoma evansi in Southeast Asia. ... in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016
zApoL1 is essential for proper blood filtration in the zebrafish glomerulus and that zApoL1 affects the expression of nephrin (show NPHS1 ELISA Kits)
Divergent intracellular biological pathways of ancestral and variant APOL1 may explain a worsened prognosis as demonstrated in Systemic Lupus Erythematosus.
Roles of APOL1 G1 and G2 variants in sickle cell disease patients: kidney is the main target.
Two APOL1 renal-risk variants are associated with longer dialysis survival in African Americans with non-diabetic end-stage renal disease.
The frequency of APOL1 risk variants ranged from 7.0% to 11.0%.
The synergy of circulating factor suPAR and APOL1 G1 or G2 on alphavbeta3 integrin activation is a mechanism for CKD.
Among African Americans with hypertension-attributed chronic kidney disease, APOL1 risk variants were not associated with an overall risk for cardiovascular disease although some signals for cardiovascular mortality were noted.
The proteomic profile of apoL1 is modified in HDLs (show CSF1R ELISA Kits) of high cardiovascular risk patients, and apoL1 plasma levels are significantly lower in serum and in HDL3 of patients that will suffer an adverse cardiac event within 3 years.
Relationships between APOL1 kidney risk variants and cardiovascular disease (CVD) susceptibility and CVD-related death remain controversial. Some studies detected an increased risk for CVD, whereas others support protection from death and subclinical CVD and cerebrovascular disease
mice with podocyte-specific expression of either APOL1 risk allele (G1 or G2), but not of the G0 allele, develop functional (albuminuria and azotemia), structural (foot-process effacement and glomerulosclerosis) and molecular (gene-expression) changes that closely resemble human kidney disease. Expression of the risk-variant APOL1 alleles interferes with endosomal trafficking and blocks autophagic flux.
APOL1 single nucleotide polymorphisms are associated with nephropathy.
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.