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anti-Apoptosis Inhibitor 5 (API5) Antibodies

API5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. Additionally we are shipping Apoptosis Inhibitor 5 Kits (6) and Apoptosis Inhibitor 5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
API5 8539 Q9BZZ5
API5 11800 O35841
API5 362170  
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Top anti-Apoptosis Inhibitor 5 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293/Jurkat/HuvEc cells, using API-5 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using API-5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to API5 on HeLa cell (antibody concentration 10 µg/mL). API5 monoclonal antibody (M01), clone 1C2 Western Blot analysis of API5 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to API5 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] API5 monoclonal antibody (M01), clone 1C2 Western Blot analysis of API5 expression in Hela S3 NE . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB API5 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the API5 antibody detected the API5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of API5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of API5 expression in HeLa (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-Apoptosis inhibitor 5 antibody, IHC(F) IHC(F): Rat Cardiac Muscle Tissue Anti-Apoptosis inhibitor 5 antibody, ICC ICC: HELA Cell 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane A: Mouse Heart lysate Lane B: Mouse Pancreas lysates probed with Rabbit Anti-API5 Polyclonal Antibody, Unconjugated (ABIN673959) at 1:300 overnight at 4 °C. Followed by HRP conjugated Goat-Anti-Rabbit IgG at 1:5000 for 90 min at 37 °C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details

API5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Apoptosis Inhibitor 5 Antibodies

  1. Human Monoclonal Apoptosis Inhibitor 5 Primary Antibody for IF, WB - ABIN394905 : Ren, Zhang, Shi, Gong: Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway. in Pathology oncology research : POR 2010 (PubMed)
    Show all 5 references for ABIN394905

  2. Human Polyclonal Apoptosis Inhibitor 5 Primary Antibody for IHC, ELISA - ABIN1534266 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  3. Human Monoclonal Apoptosis Inhibitor 5 Primary Antibody for IF, IHC (p) - ABIN521982 : Garcia-Jove Navarro, Basset, Arcondéguy, Touriol, Perez, Prats, Lacazette: Api5 contributes to E2F1 control of the G1/S cell cycle phase transition. in PLoS ONE 2013 (PubMed)

More Antibodies against Apoptosis Inhibitor 5 Interaction Partners

Human Apoptosis Inhibitor 5 (API5) interaction partners

  1. Authors propose a proapoptotic role for NP in IAV pathogenesis, whereby it suppresses expression of antiapoptotic factor API5, thus potentiating the E2F1 (show E2F1 Antibodies)-dependent apoptotic pathway and ensuring viral replication.

  2. Authors show that API5 increases the metastatic capacity of cervical cancer cells in vitro and in vivo via up-regulation of MMP-9 (show MMP9 Antibodies).

  3. rs17684886 (ZNRF1 (show ZNRF1 Antibodies)) and rs599019 (COLEC12 (show COLEC12 Antibodies)) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1 (show GORAB Antibodies)) and rs899036 (API5) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes

  4. API5 overexpression promoted cell proliferation and colony formation in CaSki cancer cells, whereas API5 knockdown inhibited the both properties in HeLa cells; API5 expression is associated with pERK1/2 in a subset of cervical cancer patients and its expression predicts poor overall survival.

  5. miR (show MLXIP Antibodies)-143 and miR (show MLXIP Antibodies)-145 and the predicted target proteins API5, ERK5 (show MAPK7 Antibodies), K-RAS (show HRAS Antibodies), and IRS-1 (show IRS1 Antibodies) display regional differences in expression in the colon

  6. Negative regulation of API-5 expression by miR-1 was demonstrated to promote apoptosis of HepG2 cells.

  7. API5 acts as an immune escape gene in tumors by rendering them resistant to apoptosis triggered by tumor antigen-specific T cells.

  8. Low miR (show MLXIP Antibodies)-224 and high API5 expression correlated with worse survival of glioblastoma patients.

  9. Api5, even if not physically interacting with E2F1 (show E2F1 Antibodies), contributes positively to E2F1 (show E2F1 Antibodies) transcriptional activity by increasing E2F1 (show E2F1 Antibodies) binding to its target promoters.

  10. structure and function of API5

Apoptosis Inhibitor 5 (API5) Antigen Profile

Protein Summary

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with API5

  • apoptosis inhibitor 5 (api5) antibody
  • apoptosis inhibitor 5 (API5) antibody
  • Apoptosis inhibitor 5 (api5) antibody
  • apoptosis inhibitor 5 (LOC100228730) antibody
  • apoptosis inhibitor 5 (Api5) antibody
  • AAC-11 antibody
  • AAC11 antibody
  • AI196452 antibody
  • API-5A antibody
  • API5 antibody
  • api5-A antibody
  • api5l1 antibody
  • MGC83290 antibody
  • sr:nyz021 antibody
  • wu:fb26c03 antibody
  • zgc:66211 antibody

Protein level used designations for API5

apoptosis inhibitor 5 , Apoptosis inhibitor 5-A , Apoptosis inhibitor 5 , apoptosis inhibitor 5-like , FIF , antiapoptosis clone 11 protein , cell migration-inducing gene 8 protein , fibroblast growth factor 2-interacting factor 2 , migration-inducing protein MIG8 , API-5 , apoptosis inhibitory protein 5

GENE ID SPECIES
321676 Danio rerio
446672 Xenopus laevis
451131 Pan troglodytes
716346 Macaca mulatta
100010659 Monodelphis domestica
100050009 Equus caballus
100078170 Ornithorhynchus anatinus
100195317 Salmo salar
100345733 Oryctolagus cuniculus
100378651 Saccoglossus kowalevskii
100380157 Xenopus (Silurana) tropicalis
100228730 Taeniopygia guttata
8539 Homo sapiens
11800 Mus musculus
362170 Rattus norvegicus
483413 Canis lupus familiaris
100522006 Sus scrofa
538968 Bos taurus
100717249 Cavia porcellus
423168 Gallus gallus
100173613 Pongo abelii
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