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Apoptotic Chromatin Condensation Inducer 1 Proteins (ACIN1)

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. Additionally we are shipping ACIN1 Antibodies (136) and ACIN1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACIN1 22985 Q9UKV3
ACIN1 56215 Q9JIX8
Rat ACIN1 ACIN1 305884  
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Top ACIN1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details

ACIN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Apoptotic Chromatin Condensation Inducer 1 (ACIN1) Interaction Partners

Human Apoptotic Chromatin Condensation Inducer 1 (ACIN1) interaction partners

  1. acinus L was identified as a potential novel mTORC1 target.

  2. Differences in the nuclear localization of Acinus-S' and Acinus-L may suggest that these two isoforms have different functional roles.

  3. the ligand-dependent splicing activity of Acinus is related to the retinoic acid-activated retinoic acid receptor (show RARA Proteins)

  4. An electronegative region on acinusS restricts SRPK2 (show SRPK2 Proteins) phosphorylation to a single specific site.

  5. Chronic low-dose radiation increases the levels of AKT (show AKT1 Proteins) and acinus proteins via NF-kappaB (show NFKB1 Proteins) activation

  6. Akt (show AKT1 Proteins) phosphorylation of acinus on serine 422 and 573 results in its resistance to caspase (show CASP3 Proteins) cleavage in the nucleus and the inhibition of acinus-dependent chromatin condensation.

  7. Acinus is not involved in DNA condensation but rather has a role in internucleosomal DNA cleavage during programmed cell death

  8. We found hypermethylation of the ACIN1 gene in early stage lung adenocarcinoma. The role of methylation status in the development and malignant transformation of lung adenocarcinoma requires clarification.

  9. identify Acinus-S' as a novel RAR (show RARA Proteins)-interacting protein[Acinus-S']

  10. The authors report here that AAC-11 (show API5 Proteins), a survival protein whose expression prevents apoptosis that occurs on deprivation of growth factors, physiologically binds to Acinus and prevents Acinus-mediated DNA fragmentation.

Mouse (Murine) Apoptotic Chromatin Condensation Inducer 1 (ACIN1) interaction partners

  1. gp70 (show EMB Proteins) enhances cellular DNA-damage-induced signaling in association with host-specific cellular proteins including acinus and MCM2 (show MCM2 Proteins) resulting in the activation of DNA-PK to phosphorylate P53 (show TP53 Proteins).

ACIN1 Protein Profile

Protein Summary

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with ACIN1

  • apoptotic chromatin condensation inducer 1b (acin1b)
  • apoptotic chromatin condensation inducer 1a (acin1a)
  • apoptotic chromatin condensation inducer 1 (acin1)
  • apoptotic chromatin condensation inducer 1 (ACIN1)
  • apoptotic chromatin condensation inducer 1 (LOC100338262)
  • apoptotic chromatin condensation inducer 1 (Acin1)
  • 2610036I19Rik protein
  • 2610510L13Rik protein
  • Acinus protein
  • acinusa protein
  • acinusb protein
  • acinusL protein
  • acinusS protein
  • Acn protein
  • C79325 protein
  • fi14c05 protein
  • fSAP152 protein
  • ik:tdsubc_2g5 protein
  • mKIAA0670 protein
  • si:zc14a17.12 protein
  • wu:fb04g06 protein
  • wu:fb40f03 protein
  • wu:fb68h03 protein
  • wu:fb80f07 protein
  • wu:fc12e10 protein
  • wu:fe06a10 protein
  • wu:fi14c05 protein
  • xx:tdsubc_2g5 protein

Protein level used designations for ACIN1

apoptotic chromatin condensation inducer in the nucleus, b , apoptotic chromatin condensation inducer in the nucleus, a , apoptotic chromatin condensation inducer 1 , apoptotic chromatin condensation inducer in the nucleus , apoptotic chromatin condensation inducer in the nucleus-like , functional spliceosome-associated protein 152 , acinus

GENE ID SPECIES
327495 Danio rerio
368893 Danio rerio
407918 Xenopus (Silurana) tropicalis
452792 Pan troglodytes
480247 Canis lupus familiaris
534600 Bos taurus
713310 Macaca mulatta
734979 Xenopus laevis
100338262 Oryctolagus cuniculus
100470890 Ailuropoda melanoleuca
100594211 Nomascus leucogenys
22985 Homo sapiens
56215 Mus musculus
305884 Rattus norvegicus
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