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APEX1 encodes a member of the Kunitz-type serine proteinase inhibitor family.
Showing 6 out of 6 products:
Human Monoclonal APEX1 Primary Antibody for IF, WB - ABIN968192
Jayaraman, Murthy, Zhu, Curran, Xanthoudakis, Prives: Identification of redox/repair protein Ref-1 as a potent activator of p53. in Genes & development 1997
Show all 3 references for ABIN968192
Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (show PRSS3 Antibodies) accumulated tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Antibodies)) in the matrix.
Hypermethylation of TFPI2 (show TFPI2 Antibodies) promoter is increased in inflamed colon tissue.
DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.
our findings suggested that the differential expression of MMP-2 (show MMP2 Antibodies) and TFPI-2 (show TFPI2 Antibodies) have a negative correlation in pancreatic carcinoma
Our finding suggests that the decreased expression of TFPI-2 (show TFPI2 Antibodies) may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma
TMPRSS4 (show TMPRSS4 Antibodies) is upregulated by silencing of TFPI-2 (show TFPI2 Antibodies) through aberrant DNA methylation (show HELLS Antibodies) and contributes to oncogenesis in non-small cell lung cancer.
TFPI-2 (show TFPI2 Antibodies) is a down-regulated tumor suppressor gene in oral squamous cell carcinoma, probably involving epigenetic silencing mechanisms. The loss of TFPI-2 (show TFPI2 Antibodies) expression is a key event for oral tumorigenesis, especially in the process of tumor metastasis.
regulation of tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Antibodies)) expression by lysine-specific demethylase (show MBD2 Antibodies) 1 and 2
TFPI-2 (show TFPI2 Antibodies) in platelets from normal or pregnant subjects and in plasma from pregnant women binds FV/Va and regulates intrinsic coagulation and fibrinolysis
TFPI-2 (show TFPI2 Antibodies) downregulation can contribute to tumor invasion of hepatocellular carcinoma cells through alteration in the expression of metastasis-related genes.
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
placental protein 5
, retinal pigment epithelium cell factor 1