anti-Apurinic/apyrimidinic Endonuclease 1 (APEX1) Antibodies

APEX1 encodes a member of the Kunitz-type serine proteinase inhibitor family.

list all antibodies Gene Name GeneID UniProt
APEX1 7980 P48307
APEX1    
APEX1    
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Top anti-Apurinic/apyrimidinic Endonuclease 1 Antibodies at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, WB Western blot analysis of Ref-1 on HeLa lysate. Lane 1:1:250, lane 2: 1:500, lane 3: 1:1000 dilution of Ref-1 FHs 50 μg Log in to see 6 to 8 Days
$220.08
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Ref-1 Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Western Blot (WB) analysis of A549 cells using Acetyl-Ref-1 (K6) Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of Jurkat, K562 cells using Acetyl-Ref-1 (K7) Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 2 to 3 Days
$653.13
Details

APEX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Apurinic/apyrimidinic Endonuclease 1 Antibodies

  1. Human Monoclonal APEX1 Primary Antibody for IF, WB - ABIN968192 : Jayaraman, Murthy, Zhu, Curran, Xanthoudakis, Prives: Identification of redox/repair protein Ref-1 as a potent activator of p53. in Genes & development 1997 (PubMed)
    Show all 3 references for 968192

More Antibodies against Apurinic/apyrimidinic Endonuclease 1 Interaction Partners

Human Apurinic/apyrimidinic Endonuclease 1 (APEX1) interaction partners

  1. our research indicated that miR (show MLXIP Antibodies)-130a functions as an oncogene (show RAB1A Antibodies) by targeting TFPI2 (show TFPI2 Antibodies), miR (show MLXIP Antibodies)-130a inhibition reduced the growth and angiogenesis of hemangioma by inactivating the FAK (show PTK2 Antibodies)/PI3K (show PIK3CA Antibodies)/Rac1/mdm2 (show MDM2 Antibodies) pathway

  2. TFPI-2 (show TFPI2 Antibodies) expression was decreased in bladder cancer. TFPI-2 (show TFPI2 Antibodies) expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis.

  3. TFPI2 (show TFPI2 Antibodies) is a useful serum biomarker for preoperative clinical diagnosis of CCC.

  4. This TPR-dependent PP5 inhibition shown by Ro 90-7501 is a unique and novel inhibitory mechanism, which might be a useful tool for studies of PP5 on both regulatory mechanism and drug discovery.

  5. Over-expression of TFPI-2 (show TFPI2 Antibodies) and aberrant promoter methylation status presented in the preeclampsia placentas, suggesting that epigenetic mechanism might contribute to the pathogenesis of preeclampsia.

  6. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (show PRSS3 Antibodies) accumulated tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Antibodies)) in the matrix.

  7. Hypermethylation of TFPI2 (show TFPI2 Antibodies) promoter is increased in inflamed colon tissue.

  8. DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.

  9. our findings suggested that the differential expression of MMP-2 (show MMP2 Antibodies) and TFPI-2 (show TFPI2 Antibodies) have a negative correlation in pancreatic carcinoma

  10. Our finding suggests that the decreased expression of TFPI-2 (show TFPI2 Antibodies) may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma

Apurinic/apyrimidinic Endonuclease 1 (APEX1) Antigen Profile

Protein Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with APEX1

  • tissue factor pathway inhibitor 2 (TFPI2) antibody
  • PP5 antibody
  • REF1 antibody
  • TFPI-2 antibody

Protein level used designations for APEX1

placental protein 5 , retinal pigment epithelium cell factor 1

GENE ID SPECIES
7980 Homo sapiens
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