Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. Additionally we are shipping Aquaporin 4 Antibodies (136) and Aquaporin 4 Kits (44) and many more products for this protein.
Showing 9 out of 9 products:
Ordered disorder of the astrocytic dystrophin (show DMD Proteins)-associated protein complex in the norm and pathology.
the AQP4 could play a role in the regulation of water balance and ion transport in the sensory cells of zebrafish, bringing new data for the utilizing of this experimental model in the biology of sensory system.
These results suggest that AQP4 is damaged first and decrease of EAAT-2 (show SLC1A2 Proteins) may follow in pathogenesis of cortical degeneration. This is the first demonstration of decrease of AQP4 and its association with EAAT-2 (show SLC1A2 Proteins) decrease in AIDS brain, suggesting a role in the pathogenesis of HIV-associated neurocognitive disorders.
Study concludes from direct measurement of deterministic molecular dynamics in conjunction with applied-field metadynamics that the intrinsic electric field within the AQP4 channel points along the +z-axis, such that externally applied static fields in this direction serve to "open" the channel in the selectivity-filter and the asparagine-proline-alanine region.
Results indicate that T-cells bearing characteristics of both Th1 (show TH1L Proteins) and Th17 T-cells and targeting specific immunodominant epitopes of the AQP4 protein might be involved in the pathogenesis of Neuromyelitis optica
AQP4 antibody associated optic neuritis tends to involve the posterior optic pathway.
Our results suggest that AQP5 (show AQP5 Proteins) but not AQP4 contributes to salivary secretion in patients with Sjogren's syndrome, including those with neuromyelitis optica complicated with Sjogren's syndrome.
Administration of E1 + P1 and E1 + P2 decreased the inhibitory effect of E1 on the IL-6 (show IL6 Proteins) levels and AQP4 protein expression
Study shows that the processing of AQP4 by antigen presenting cells in Lewis rats produces a highly encephalitogenic AQP4 epitope (AQP4268-285)
The induction of antibodies to an AQP4 epitope in mice immunized with the TAX1BP1 (show TAX1BP1 Proteins)-derived peptide suggests that a latent HTLV-1 infection could lead to TAX1BP1 (show TAX1BP1 Proteins) antigen presentation and the production of anti-AQP4 antibodies in human neuromyelitis optica.
Based on a comparative mutagenic analysis of AQP1 (show AQP1 Proteins), AQP 3 (show AQP3 Proteins), and AQP 4, the results suggest that loop D interactions may provide a general structural framework for tetrameric assembly within the AQP family.
The study demonstrated the abnormal expression pattern of AQP1 (show AQP1 Proteins), AQP2 (show AQP2 Proteins), AQP3 (show AQP3 Proteins), and AQP4 in the kidney tissues of patients with nephrotic syndrome, providing a basis for an improved understanding of the role of aquaporins in the pathogenesis of this disease.
This study demonstrated that Subcellular localization of Aqp4 was compared between cortical and white matter astrocytes in postmortem specimens of patients with focal ischemic stroke versus controls.
TRPV4 (show TRPV4 Proteins)-AQP4 interactions 'turbocharge' astroglial sensitivity to small osmotic gradients
Elevation of AQP4 and selective cytokines in experimental autoimmune encephalitis mice provides some potential biomarkers in optic neuritis and demyelinating diseases.
This study provided the AQP4 modulates astrocyte-to-microglia communication in neuroinflammation.
AQP4 attenuates Abeta (show APP Proteins) pathogenesis despite its potentially inflammatory side-effects, thus serving as a promising target for treating Alzheimer's disease
mildly improved outcome in AQP4(-/-) mice following cortical impact injury results from reduced cytotoxic brain water
glial AQP4 is involved in the susceptibility differences of dopamine neurons between the substantia nigra and ventral tegmental area
Study characterized the brain distribution of aquaporin-4 and found that expression was high in the cerebellum and areas associated with water movement
These results demonstrate that AQP4 effects on [K(+)]e and ECS volume dynamics accelerate CSD (show CSAD Proteins) propagation.
AQP4 expression increased after traumatic brain injury and was positively correlated with edema and neurological impairments.
AQP4 plays an important role in mediating brain edema in hypoxic-ischemic encephalopathy.
constitutive recycling of AQP2 (show AQP2 Proteins) does not require phosphorylation at any C-terminal sites
In conclusion, HPO (show GFER Proteins) can decrease AQP4 expression in brain tissue of rabbits with cerebral hemorrhage to suppress the progression of brain edema and promote repairing of injured tissue.
AQP4 may play an important role in brain edema after severe scald (show RDH11 Proteins).
In the guinea pig AQP4 is localised to enteric glial cells.
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
, aquaporin 4
, aquaporin type4
, mercurial-insensitive water channel
, aquaporin 4.M23
, mercurial insensitive water channel
, water channel