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anti-Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B) Antibodies

ALOX12B encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Additionally we are shipping ALOX12B Proteins (5) and ALOX12B Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX12B 242 O75342
ALOX12B 11686 O70582
ALOX12B 287425 Q2KMM4
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Top anti-ALOX12B Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB ALOX12B antibody (C-term) (ABIN654058) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ALOX12B Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ALOX12B antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ALOX12B antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB ALOX12B polyclonal antibody (A01), Lot # 051130JC01 Western Blot analysis of ALOX12B expression in Jurkat . Western Blot detection against Immunogen (36.12 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

ALOX12B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-ALOX12B Antibodies

  1. Human Polyclonal ALOX12B Primary Antibody for EIA, IHC (p) - ABIN950354 : Vahlquist, Bygum, Gånemo, Virtanen, Hellström-Pigg, Strauss, Brandrup, Fischer: Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients. in The Journal of investigative dermatology 2010 (PubMed)
    Show all 5 references for ABIN950354

  2. Human Polyclonal ALOX12B Primary Antibody for ELISA, WB - ABIN559855 : Nigam, Zafiriou, Deva, Kerstin, Geilen, Ciccoli, Sczepanski, Lohse: Hepoxilin A3 (HXA3) synthase deficiency is causative of a novel ichthyosis form. in FEBS letters 2008 (PubMed)
    Show all 2 references for ABIN559855

  3. Human Polyclonal ALOX12B Primary Antibody for FACS, IHC (p) - ABIN654058 : Han, Lan, Park, Lee, Park, Ahn, Shin, Kang, Koo, Seo, Choi, Ahn, Chanock, Kim, Rothman, Kang: Polymorphisms in innate immunity genes and risk of childhood leukemia. in Human immunology 2010 (PubMed)

More Antibodies against ALOX12B Interaction Partners

Human Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B) interaction partners

  1. We found that the contribution of the ALOX12B gene to the pathogenesis of Autosomal Recessive Congenital Ichthyosis (show LBR Antibodies) to be as important as that of TGM1 (show TGM1 Antibodies) in families of Arab Muslim origin

  2. Loss-of-function mutations in the LOX (show LOX Antibodies) genes ALOX12B and ALOXE3 (show ALOXE3 Antibodies) have been found to represent the second most common cause of autosomal recessive congenital ichthyosis (show LBR Antibodies). [review]

  3. This review covers the background to discovery of the two key lipoxygenases (LOX (show LOX Antibodies)) involved in epidermal barrier function, 12R-LOX and eLOX3 (show ALOXE3 Antibodies). [review]

  4. Autosomal recessive congenital ichthyosis (show LBR Antibodies) patients with NIPAL4 (show NIPAL4 Antibodies) mutations and abnormal ichthyin (show NIPAL4 Antibodies) expression showed increased 12R-LOX and eLOX-3 (show ALOXE3 Antibodies) staining and a colocalization signal of these LOXs that was three times the normal intensity.

  5. It was shown that 12R-lipoxygenase is involved in MUC5AC expression via ERK (show EPHB2 Antibodies)- and Sp1 (show PSG1 Antibodies)-signalling pathways.

  6. co-overproduction of the two chaperones with 12R-LOX resulted in increased solubility of 12R-LOX and allowed the purification of milligram amounts of active enzyme for structural studies by X-ray diffraction

  7. ALOX12B mutations are the leading cause of self-improving collodion ichthyosis (show LBR Antibodies) in Scandinavia, followed by ALOXE3 (show ALOXE3 Antibodies) mutations, and TGM1 (show TGM1 Antibodies) mutations

  8. 12-R-LOX (show LOX Antibodies) and COX-2 (show COX2 Antibodies) play critical roles in the regulation of growth in epidermoid carcinoma

  9. Lipoxygenase-3 (ALOXE3 (show ALOXE3 Antibodies)) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.

  10. 12R-LOX hydrolase functions in the normal process of skin differentiation, and that the loss of function mutations are the basis of the LOX (show LOX Antibodies)-dependent form of Non-bullous congenital ichthyosiform erythroderma.

Mouse (Murine) Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B) interaction partners

  1. Loss-of-function mutations in the LOX (show LOX Antibodies) genes ALOX12B and ALOXE3 (show ALOXE3 Antibodies) have been found to represent the second most common cause of autosomal recessive congenital ichthyosis (show LBR Antibodies). [review]

  2. The 12R-LOX-eLOX-3 (show ALOXE3 Antibodies) pathway plays a key role in the process of epidermal barrier acquisition by affecting lipid metabolism, as well as protein processing.

  3. Alox12b-deficient mouse skin transplants have an ichthyosiform phenotype

ALOX12B Antigen Profile

Protein Summary

This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.

Gene names and symbols associated with ALOX12B

  • arachidonate 12-lipoxygenase, 12R type (ALOX12B) antibody
  • arachidonate 12-lipoxygenase, 12R type (alox12b) antibody
  • arachidonate 12-lipoxygenase, 12R type (Alox12b) antibody
  • 12R-LOX antibody
  • ALOX12B antibody
  • Aloxe2 antibody
  • ARCI2 antibody
  • e-LOX2 antibody
  • MGC85124 antibody
  • MGC107915 antibody

Protein level used designations for ALOX12B

arachidonate 12-lipoxygenase, 12R type , arachidonate 12-lipoxygenase, 12R-type , arachidonate 12-lipoxygenase, 12R type-like , arachidonate 12-lipoxygenase, 12R-type-like , 12R-lipoxygenase , epidermis-type lipoxygenase 12 , 12R-LOX , e-LOX 2 , epidermis-type lipoxygenase 2

GENE ID SPECIES
455103 Pan troglodytes
489486 Canis lupus familiaris
504803 Bos taurus
548458 Xenopus (Silurana) tropicalis
721936 Macaca mulatta
734312 Xenopus laevis
100062323 Equus caballus
100390364 Callithrix jacchus
100474976 Ailuropoda melanoleuca
100526246 Sus scrofa
242 Homo sapiens
11686 Mus musculus
287425 Rattus norvegicus
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