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Arachidonate 15-Lipoxygenase Proteins (ALOX15)

demonstrates 12-lipoxygenase and some 15-lipoxygenase enzyme activity [RGD, Feb 2006].. Additionally we are shipping Arachidonate 15-Lipoxygenase Antibodies (63) and Arachidonate 15-Lipoxygenase Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALOX15 246 P16050
ALOX15 11687 P39654
Rat ALOX15 ALOX15 81639 Q02759
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Top Arachidonate 15-Lipoxygenase Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

ALOX15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Arachidonate 15-Lipoxygenase (ALOX15) Interaction Partners

Pig (Porcine) Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. The crystal structure of a mammalian 12-lipoxygenase reveals a plausible substrate access channel for oxygen.

  2. 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1.

  3. EPR (show EREG Proteins) spectroscopy and electrospray mass spectroscopy reveal distinctive features of the iron site in leukocyte arachidonate 12-lipoxygenase (show ALOX12 Proteins).

Human Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. Hypoxia increase the production of ROS (show ROS1 Proteins) through the 15-Lipoxygenase/15-Hydroxyeicosatetraenoiccid pathway.

  2. The role of 15-LOX-1 in colitis and colitis-associated colorectal cancer

  3. variation in inflammation related genes ALOX15 and IL6 (show IL6 Proteins) was associated with bone microarchitecture and density in young adult women, but appears to be less important in the elderly

  4. Significant associations with NSAID-exacerbated respiratory disease were identified for: ALOX15 homozygous genotype and PTGS-1 (show PTGS1 Proteins) rs5789 A/A homozygous genotype

  5. limiting ALOX15 expression by AMPK (show PRKAA1 Proteins) may promote an anti-inflammatory phenotype of IL-4 (show IL4 Proteins)-stimulated human macrophages

  6. Effect of 12/15-LOX on colorectal tumorigenesis in mouse models could be affected by tumor cell type (human or mouse), relative 12/15 LOX activity in tumor cells and stroma as well as the relative tumor 13-HODE and 12-HETE levels.

  7. IGF-1 (show IGF1 Proteins) reduces lipid oxidation and foam cell formation via downregulation of 12/15-LOX to prevent atherosclerosis.

  8. enzymatic activity and the intracellular membrane-binding function of 15-LO1 appear to contribute to HIF-1alpha (show HIF1A Proteins) suppression

  9. These findings demonstrate that 15-LOX-1 expression loss in cancer cells promotes metastasis and that therapeutically targeting ubiquitous 15-LOX-1 loss in cancer cells has the potential to suppress metastasis.

  10. Loss of Alox15 altered expression of PTEN, PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins), and the transcription factor ICSBP (show IRF8 Proteins)

Rabbit Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. Results indicate 15-lipoxygenase modified LDL as a new inducer for LOX-1 (show OLR1 Proteins) expression and as a new ligand for LOX-1 (show OLR1 Proteins).

Mouse (Murine) Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. In experimental postoperative ileus, 12/15-lipoxygenase was expressed, mainly in CX3CR1 (show CX3CR1 Proteins)(+)/Ly6C(+) infiltrating monocytes, not Ly6G(+) neutrophils. 12/15-LOX mediates ileus resolution by producing proresolving docosahexaenoic acid-derived protectin (show CD59 Proteins) DX.

  2. we show that oxidized phospholipids generated by 12/15-LOX can act as substrates for key proteins required for effective autophagy and that cells deficient in this enzyme show evidence of autophagic dysfunction

  3. SHH (show SHH Proteins)-responsive 5-lipoxygenase (show ALOX5 Proteins), 15-lipoxygenase and COX-2 modulate Dectin-1 (show CLEC7A Proteins)-induced inflammatory cytokines.

  4. Effect of 12/15-LOX on colorectal tumorigenesis in mouse models could be affected by tumor cell type (human or mouse), relative 12/15 LOX activity in tumor cells and stroma as well as the relative tumor 13-HODE and 12-HETE levels.

  5. These observations provide novel insights on the role of XO in 12/15-LO-induced JamA (show F11R Proteins) tyrosine phosphorylation and TJ disruption leading to increased vascular permeability in response to HFD.

  6. IGF-1 (show IGF1 Proteins) reduces lipid oxidation and foam cell formation via downregulation of 12/15-LOX to prevent atherosclerosis.

  7. Inactivation of the Alox15 gene does not rescue homozygous knock-in mice expressing catalytically silent Gpx4 (show GPX4 Proteins).

  8. Data indicate that interleukin-6 (IL-6 (show IL6 Proteins))/signal transducer and activator of transcription 3 (STAT3 (show STAT3 Proteins)) signaling pathway.

  9. 12/15-LO determined the DC activation threshold by generating phospholipid oxidation products and a NRF2 (show NFE2L2 Proteins)-dependent antioxidative response. Deletion or inhibition accelerated maturation and shifted the cytokine profile to favor TH17 cell differentiation.

  10. This study demonstrated that lipoxygenases act cell autonomously within neurons to regulate degeneration, and are required for mitochondrial permeabilization and caspase (show CASP3 Proteins) activation in the axon

Arachidonate 15-Lipoxygenase (ALOX15) Protein Profile

Protein Summary

demonstrates 12-lipoxygenase and some 15-lipoxygenase enzyme activity

Gene names and symbols associated with ALOX15

  • arachidonate 15-lipoxygenase (ALOX15)
  • arachidonate 15-lipoxygenase (Nmul_A0532)
  • arachidonate 15-lipoxygenase (Sden_1680)
  • arachidonate 15-lipoxygenase (Swoo_2919)
  • Arachidonate 15-lipoxygenase (PCC8801_3106)
  • Arachidonate 15-lipoxygenase (Cyan8802_3014)
  • Arachidonate 15-lipoxygenase (Nwat_1315)
  • arachidonate 12-lipoxygenase (ALOX12)
  • arachidonate 15-lipoxygenase (Alox15)
  • 12-LO protein
  • 12-LOX protein
  • 15-LOX protein
  • 15-LOX-1 protein
  • 15LOX-1 protein
  • Alox12 protein
  • Alox12l protein
  • ALOX15 protein
  • L-12LO protein

Protein level used designations for ALOX15

arachidonate 15-lipoxygenase , Arachidonate 15-lipoxygenase , 12S-LOX , 12S-lipoxygenase , arachidonate 12-lipoxygenase, 12S-type , 15-LOX , 15-lipooxygenase-1 , arachidonate omega-6 lipoxygenase , 12-LOX , erythroid cell-specific 15-lipoxygenase , lipoxygenase , omega-6 lipoxygenase , arachidonate 12-lipoxygenase, leukocyte-type , 12/15-LOX

GENE ID SPECIES
748294 Pan troglodytes
3784521 Nitrosospira multiformis ATCC 25196
4018156 Shewanella denitrificans OS217
6117234 Shewanella woodyi ATCC 51908
7102416 Cyanothece sp. PCC 8801
8392342 Cyanothece sp. PCC 8802
9392786 Nitrosococcus watsonii C-113
396971 Sus scrofa
246 Homo sapiens
489458 Canis lupus familiaris
282139 Bos taurus
100009114 Oryctolagus cuniculus
11687 Mus musculus
81639 Rattus norvegicus
100174413 Pongo abelii
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