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anti-Arachidonate 5-Lipoxygenase (ALOX5) Antibodies

ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. Additionally we are shipping ALOX5 Kits (70) and ALOX5 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX5 240 P09917
ALOX5 25290 P12527
ALOX5 11689 P48999
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Top anti-ALOX5 Antibodies at antibodies-online.com

Showing 10 out of 170 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using Arachidonate... Immunohistochemistry analysis of paraffin-embedded human skeletal musc... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185698 (0.3µg/ml) staining of Rat Stomach lysate (35µg protein in ... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of 5-Lipoxygenase on SL-29 lysate. Lane 1: 1:250... Immunofluorescence staining of A431 cells 50 μg Log in to see 5 to 6 Days
$205.42
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Hamster Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using Arachidonate... Immunohistochemistry analysis of paraffin-embedded human skeletal musc... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details

ALOX5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Rat (Rattus) , , , ,
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Mouse (Murine) , , , ,
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Top referenced anti-ALOX5 Antibodies

  1. Chicken Monoclonal ALOX5 Primary Antibody for IF, IP - ABIN968116 : Hundley, Prasad, Beaven: Elevated levels of cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 5 references for ABIN968116

  2. Human Polyclonal ALOX5 Primary Antibody for WB - ABIN372586 : Dwyer, Allayee, Dwyer, Fan, Wu, Mar, Lusis, Mehrabian: Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. in The New England journal of medicine 2004 (PubMed)
    Show all 5 references for ABIN372586

  3. Human Polyclonal ALOX5 Primary Antibody for ELISA, WB - ABIN185698 : Kalayci, Birben, Sackesen, Keskin, Tahan, Wechsler, Civelek, Soyer, Adalioglu, Tuncer, Israel, Lilly: ALOX5 promoter genotype, asthma severity and LTC production by eosinophils. in Allergy 2005 (PubMed)

  4. Human Polyclonal ALOX5 Primary Antibody for IHC, ELISA - ABIN1532500 : Mancini, Ortiz, Croxatto, Gallo: Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet. in BMC ophthalmology 2013 (PubMed)

  5. Human Polyclonal ALOX5 Primary Antibody for IF (p), IHC (p) - ABIN669651 : Wang, Wang, Gao, Qu: The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. in Drug discoveries & therapeutics 2014 (PubMed)

More Antibodies against ALOX5 Interaction Partners

Human Arachidonate 5-Lipoxygenase (ALOX5) interaction partners

  1. AF4 and AF4-MLL (show MLL Antibodies) mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3.

  2. the Alox-5 gene (show GPD1 Antibodies) might play a role in the differentiation of multiple drug resistant and non-resistant erythroleukemic cell lines

  3. These results suggest that COX-2 (show COX2 Antibodies) and 5-LO play roles in tumorigenesis and the progression of primary glioblastoma and that the co-expression pattern of COX-2 (show COX2 Antibodies)/5-LO may be used as an independent prognostic factor in this disease.

  4. Increased PUFA Content and 5-lipoxygenase pathway expression are associated with subcutaneous adipose tissue inflammation in obese women with type 2 diabetes.

  5. The study shows that 5-lipoxygenase (5-LO) in B cells is phosphorylated on Ser523 and demonstrates for the first time a chemical difference between 5-LO in myeloid cells and B cells.

  6. Study identified a novel splice variant of 5-LO consisting of 139 amino acids due to premature stop. It was found to be expressed in HepG2 cells only, raising the possibility for putative role in liver cancer development.

  7. GSAP (show PION Antibodies) cleavage via caspase-3 (show CASP3 Antibodies) is regulated and depend upon the availability of 5-Lipoxygenase in Alzheimer's disease.

  8. investigated potential mechanisms by which 5-LO13 interferes with 5-LO product biosynthesis in transfected HEK293 cells

  9. Two of the most potent/selective inhibitors (HIR (show KCNJ4 Antibodies)-303 and HIR (show KCNJ4 Antibodies)-309) were reductive inhibitors and were potent against 5-LOX in human whole blood, indicating that isoflavans can be potent and selective inhibitors against human leukocyte 5-LOX

  10. The study explores the substrate access portal of 5-Lipoxygenase.

Mouse (Murine) Arachidonate 5-Lipoxygenase (ALOX5) interaction partners

  1. Results establish a key role of 5-Lipoxygenase in the development of the tau pathology phenotype and demonstrate it to be a novel viable therapeutic target for the pharmacologic treatment of human tauopathy.

  2. GSAP (show PION Antibodies) cleavage via caspase-3 (show CASP3 Antibodies) is regulated and depend upon the availability of 5-Lipoxygenase in Alzheimer's disease.

  3. SHH (show SHH Antibodies)-responsive 5-lipoxygenase, 15-lipoxygenase and COX-2 (show COX2 Antibodies) modulate Dectin-1 (show CLEC7A Antibodies)-induced inflammatory cytokines.

  4. involvement of lipoxygenase pathways in TNF-alpha (show TNF Antibodies)-induced production of cytokines and chemokines

  5. explored the relationship between 5-LO and central and peripheral eosinophilia in an asthma model using PAS (show PASK Antibodies) or BALB/c mice and 5-LO-deficient mutants

  6. ALOX5 deficiency prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease.

  7. 5-LO activation coordinates the inflammatory immune response involved in the control of visceral leishmaniasis.

  8. 5-LO(-/-) mice subjected to kidney insult presented lower macrophage infiltration and higher levels of IL-10 (show IL10 Antibodies) than wild-type mice.

  9. Alox5 affects the osteogenic and adipogenic abilities of iPSCs in vivo and the effect of Cox2 (show COX2 Antibodies) inhibition in this system.

  10. Data show that resolvin D1 decrease nuclear 5-lipoxygenase (5-LOX) and the leukotrienes LTB4 (show PTGR1 Antibodies):LXA4 ratio by macrophages lacking calcium-sensitive kinase calcium-calmodulin-dependent protein kinase II (CaMKII (show CAMK2 Antibodies)).

ALOX5 Antigen Profile

Protein Summary

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ALOX5

  • arachidonate 5-lipoxygenase (alox5) antibody
  • arachidonate 5-lipoxygenase (AFUA_4G02770) antibody
  • arachidonate 5-lipoxygenase (AOR_1_1362014) antibody
  • Arachidonate 5-lipoxygenase (lox5) antibody
  • arachidonate 5-lipoxygenase (ALOX5) antibody
  • arachidonate 5-lipoxygenase (Alox5) antibody
  • arachidonate 5-lipoxygenase (LOC100341714) antibody
  • 5-LO antibody
  • 5-LOX antibody
  • 5LO antibody
  • 5LPG antibody
  • 5LX antibody
  • AI850497 antibody
  • F730011J02 antibody
  • LOG5 antibody
  • lox5 antibody
  • LOX5A antibody
  • si:dkey-194n13.2 antibody

Protein level used designations for ALOX5

LOX2 , arachidonate 5-lipoxygenase , Arachidonate 5-lipoxygenase , LOX-5 , arachidonic 5-lipoxygenase alpha-10 isoform , arachidonic 5-lipoxygenase delta-10-13 isoform , arachidonic 5-lipoxygenase delta-13 isoform , arachidonic 5-lipoxygenase delta-p10 isoform , arachidonic acid 5-lipoxygenase , leukotriene A4 synthase , 5 - Lipoxygenase , 5-LO , 5-lipoxygenase

GENE ID SPECIES
567204 Danio rerio
3503886 Aspergillus fumigatus Af293
5994193 Aspergillus oryzae RIB40
100194803 Salmo salar
240 Homo sapiens
25290 Rattus norvegicus
477753 Canis lupus familiaris
11689 Mus musculus
100341714 Oryctolagus cuniculus
100718093 Cavia porcellus
100156205 Sus scrofa
404074 Bos taurus
423769 Gallus gallus
101117390 Ovis aries
101839970 Mesocricetus auratus
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