anti-Arachidonate 5-Lipoxygenase (ALOX5) Antibodies

ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. Additionally we are shipping ALOX5 Kits (62) and ALOX5 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX5 240 P09917
ALOX5 25290 P12527
ALOX5 11689 P48999
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Top anti-ALOX5 Antibodies at antibodies-online.com

Showing 10 out of 201 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using Arachidonate 5 Lipoxygenase (Ab-271) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Arachidonate 5 Lipoxygenase (Ab-271) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185698 (0.3µg/ml) staining of Rat Stomach lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated ICC, IF, SimWes, WB Detection of LOX5 in human peripheral leukocytes using ABIN258593 at 0.5(Lane 1) and 2.0 ug/ml (Lane 2). Simple Western: 5-Lipoxygenase Antibody [ABIN2585938] - Simple Western lane view shows a specific band for 5-Lipoxygenase in 0.5 mg/ml of Human Lung lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. * Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of 5-Lipoxygenase on SL-29 lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilultion of 5-Lipoxygenase. Immunofluorescence staining of A431 cells 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ALOX5 Picoband antibody,  IHC(P): Mouse Brain Tissue Anti-ALOX5 Picoband antibody,  IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-5 lipoxygenase/ALOX5 Polyclonal Antibody, Unconjugated (ABIN669651) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Hamster Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-5 Lipoxygenase antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details

ALOX5 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-ALOX5 Antibodies

  1. Chicken Monoclonal ALOX5 Primary Antibody for IF, IP - ABIN968116 : Hundley, Prasad, Beaven: Elevated levels of cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 5 references for 968116

  2. Human Polyclonal ALOX5 Primary Antibody for IF (p), IHC (p) - ABIN669651 : Wang, Wang, Gao, Qu: The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. in Drug discoveries & therapeutics 2014 (PubMed)
    Show all 2 references for 669651

  3. Human Polyclonal ALOX5 Primary Antibody for IHC, ELISA - ABIN1532500 : Mancini, Ortiz, Croxatto, Gallo: Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet. in BMC ophthalmology 2013 (PubMed)

  4. Human Polyclonal ALOX5 Primary Antibody for ICC, IF - ABIN258593 : Lin, Lin, Wu, Chiu, Tang, Hour, Liou, Tu, Yang, Fu: 5-Lipoxygenase inhibitors attenuate TNF-α-induced inflammation in human synovial fibroblasts. in PLoS ONE 2014 (PubMed)

  5. Human Polyclonal ALOX5 Primary Antibody for ELISA, WB - ABIN185698 : Kalayci, Birben, Sackesen, Keskin, Tahan, Wechsler, Civelek, Soyer, Adalioglu, Tuncer, Israel, Lilly: ALOX5 promoter genotype, asthma severity and LTC production by eosinophils. in Allergy 2005 (PubMed)

More Antibodies against ALOX5 Interaction Partners

Human Arachidonate 5-Lipoxygenase (ALOX5) interaction partners

  1. The observation that the coexpression of FLAP (show ALOX5AP Antibodies) with a subset of the 5-LOX mutants restores 5-LOX-wild-type (wt)-like levels of products formed in intact cells suggests a physical protein-protein interaction, beyond colocalization, of 5-LOX and FLAP (show ALOX5AP Antibodies).

  2. Polymorphisms in the 5-Lipoxygenase is associated with Incident Myocardial Infarction.

  3. our results define Alox5 as a key genetic effector of JAK2V617F in driving polycythemia vera (show IGF2BP3 Antibodies)

  4. Adipose tissue eicosapentaenoic acid and arachidonic acid and the ALOX-5 tandem repeat polymorphism did not significantly interact to affect the risk of myocardial infarction.

  5. coexpression of the isoforms inhibited or stimulated 5-LO-WT expression in transiently and stably transfected HEK293T cells suggesting that the isoforms have other functions than canonical leukotriene biosynthesis

  6. a novel putative protein isoform of human 5-LO that lacks exon 4, termed 5-LODelta4, was identified.

  7. Oxidative stress decreased the levels of PNPLA2 (show PNPLA2 Antibodies) transcripts with no effect on ALOX5 expression. Exogenous additions of P1 peptide or overexpression of the PNPLA2 (show PNPLA2 Antibodies) gene decreased both LTB4 (show PTGR1 Antibodies) levels and death of RPE (show RPE Antibodies) cells undergoing oxidative stress.

  8. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ Antibodies), lipoxygenase and cyclooxygenase.

  9. Copy number variation in ALOX5 is associated with NSAIDs-induced urticaria and/or angioedema.

  10. This study identified a SNP (rs10507391) in ALOX5 gene as a novel genetic risk factor for Alzheimer's disease and body mass index.

Mouse (Murine) Arachidonate 5-Lipoxygenase (ALOX5) interaction partners

  1. This study demonstrates that LTB4 (show PTGR1 Antibodies) promotes macrophage phagocytosis of bacteria via BLT1, and that BLT2 (show LTB4R2 Antibodies) can fulfill this role in the absence of BL

  2. our results define Alox5 as a key genetic effector of JAK2V617F in driving polycythemia vera (show IGF2BP3 Antibodies)

  3. Homocysteine directly influences 5LO expression levels and establish a previously unknown cross talk between these two pathways.

  4. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ Antibodies), lipoxygenase and cyclooxygenase.

  5. Data suggest that miR (show MLXIP Antibodies)-674-5p (microRNA-674-5p) serves as a negative regulator in 5-LO (arachidonate 5-lipoxygenase) mediated autoimmune liver injury; miR (show MLXIP Antibodies)-674-5p represses expression of 5-LO in hepatocytes in the presence of IL-6 (interleukin-6 (show IL6 Antibodies)) or TNFa (tumor necrosis factor-alpha (show TNF Antibodies)).

  6. Results establish a key role of 5-Lipoxygenase in the development of the tau pathology phenotype and demonstrate it to be a novel viable therapeutic target for the pharmacologic treatment of human tauopathy.

  7. GSAP (show PION Antibodies) cleavage via caspase-3 (show CASP3 Antibodies) is regulated and depend upon the availability of 5-Lipoxygenase in Alzheimer's disease.

  8. SHH (show SHH Antibodies)-responsive 5-lipoxygenase, 15-lipoxygenase and COX-2 (show COX2 Antibodies) modulate Dectin-1 (show CLEC7A Antibodies)-induced inflammatory cytokines.

  9. involvement of lipoxygenase pathways in TNF-alpha (show TNF Antibodies)-induced production of cytokines and chemokines

  10. explored the relationship between 5-LO and central and peripheral eosinophilia in an asthma model using PAS (show PASK Antibodies) or BALB/c mice and 5-LO-deficient mutants

ALOX5 Antigen Profile

Protein Summary

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ALOX5

  • arachidonate 5-lipoxygenase (alox5) antibody
  • arachidonate 5-lipoxygenase (AFUA_4G02770) antibody
  • arachidonate 5-lipoxygenase (AOR_1_1362014) antibody
  • Arachidonate 5-lipoxygenase (lox5) antibody
  • arachidonate 5-lipoxygenase (ALOX5) antibody
  • arachidonate 5-lipoxygenase (Alox5) antibody
  • arachidonate 5-lipoxygenase (LOC100341714) antibody
  • 5-LO antibody
  • 5-LOX antibody
  • 5LO antibody
  • 5LPG antibody
  • 5LX antibody
  • AI850497 antibody
  • F730011J02 antibody
  • LOG5 antibody
  • lox5 antibody
  • LOX5A antibody
  • si:dkey-194n13.2 antibody

Protein level used designations for ALOX5

LOX2 , arachidonate 5-lipoxygenase , Arachidonate 5-lipoxygenase , LOX-5 , arachidonic 5-lipoxygenase alpha-10 isoform , arachidonic 5-lipoxygenase delta-10-13 isoform , arachidonic 5-lipoxygenase delta-13 isoform , arachidonic 5-lipoxygenase delta-p10 isoform , arachidonic acid 5-lipoxygenase , leukotriene A4 synthase , 5 - Lipoxygenase , 5-LO , 5-lipoxygenase

GENE ID SPECIES
567204 Danio rerio
3503886 Aspergillus fumigatus Af293
5994193 Aspergillus oryzae RIB40
100194803 Salmo salar
240 Homo sapiens
25290 Rattus norvegicus
477753 Canis lupus familiaris
11689 Mus musculus
100341714 Oryctolagus cuniculus
100718093 Cavia porcellus
100156205 Sus scrofa
404074 Bos taurus
423769 Gallus gallus
101117390 Ovis aries
101839970 Mesocricetus auratus
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