Arachidonate 5-Lipoxygenase (ALOX5) ELISA Kits

ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. Additionally we are shipping ALOX5 Antibodies (202) and ALOX5 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ALOX5 240 P09917
ALOX5 25290 P12527
ALOX5 11689 P48999
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Top ALOX5 ELISA Kits at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
Details
Mouse 0.058 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$891.06
Details
Rat 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
Details
Human 0.078 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Mouse 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced ALOX5 ELISA Kits

  1. Human ALOX5 ELISA Kit for Sandwich ELISA - ABIN832344 : van der Laan, Foroughi Asl, van den Borne, van Setten, van der Perk, van de Weg, Schoneveld, de Kleijn, Michoel, Björkegren, den Ruijter, Asselbergs, de Bakker, Pasterkamp: Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study. in Atherosclerosis 2015 (PubMed)

More ELISA Kits for ALOX5 Interaction Partners

Human Arachidonate 5-Lipoxygenase (ALOX5) interaction partners

  1. The observation that the coexpression of FLAP (show ALOX5AP ELISA Kits) with a subset of the 5-LOX mutants restores 5-LOX-wild-type (wt)-like levels of products formed in intact cells suggests a physical protein-protein interaction, beyond colocalization, of 5-LOX and FLAP (show ALOX5AP ELISA Kits).

  2. Polymorphisms in the 5-Lipoxygenase is associated with Incident Myocardial Infarction.

  3. our results define Alox5 as a key genetic effector of JAK2V617F in driving polycythemia vera (show IGF2BP3 ELISA Kits)

  4. Adipose tissue eicosapentaenoic acid and arachidonic acid and the ALOX-5 tandem repeat polymorphism did not significantly interact to affect the risk of myocardial infarction.

  5. coexpression of the isoforms inhibited or stimulated 5-LO-WT expression in transiently and stably transfected HEK293T cells suggesting that the isoforms have other functions than canonical leukotriene biosynthesis

  6. a novel putative protein isoform of human 5-LO that lacks exon 4, termed 5-LODelta4, was identified.

  7. Oxidative stress decreased the levels of PNPLA2 transcripts with no effect on ALOX5 expression. Exogenous additions of P1 peptide or overexpression of the PNPLA2 gene decreased both LTB4 levels and death of RPE cells undergoing oxidative stress.

  8. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ ELISA Kits), lipoxygenase and cyclooxygenase.

  9. Copy number variation in ALOX5 is associated with NSAIDs-induced urticaria and/or angioedema.

  10. This study identified a SNP (rs10507391) in ALOX5 gene as a novel genetic risk factor for Alzheimer's disease and body mass index.

Mouse (Murine) Arachidonate 5-Lipoxygenase (ALOX5) interaction partners

  1. This study demonstrates that LTB4 (show PTGR1 ELISA Kits) promotes macrophage phagocytosis of bacteria via BLT1, and that BLT2 (show LTB4R2 ELISA Kits) can fulfill this role in the absence of BL

  2. our results define Alox5 as a key genetic effector of JAK2V617F in driving polycythemia vera (show IGF2BP3 ELISA Kits)

  3. Homocysteine directly influences 5LO expression levels and establish a previously unknown cross talk between these two pathways.

  4. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ ELISA Kits), lipoxygenase and cyclooxygenase.

  5. Data suggest that miR (show MLXIP ELISA Kits)-674-5p (microRNA-674-5p) serves as a negative regulator in 5-LO (arachidonate 5-lipoxygenase) mediated autoimmune liver injury; miR (show MLXIP ELISA Kits)-674-5p represses expression of 5-LO in hepatocytes in the presence of IL-6 (interleukin-6 (show IL6 ELISA Kits)) or TNFa (tumor necrosis factor-alpha (show TNF ELISA Kits)).

  6. Results establish a key role of 5-Lipoxygenase in the development of the tau pathology phenotype and demonstrate it to be a novel viable therapeutic target for the pharmacologic treatment of human tauopathy.

  7. GSAP (show PION ELISA Kits) cleavage via caspase-3 (show CASP3 ELISA Kits) is regulated and depend upon the availability of 5-Lipoxygenase in Alzheimer's disease.

  8. SHH (show SHH ELISA Kits)-responsive 5-lipoxygenase, 15-lipoxygenase and COX-2 (show COX2 ELISA Kits) modulate Dectin-1 (show CLEC7A ELISA Kits)-induced inflammatory cytokines.

  9. involvement of lipoxygenase pathways in TNF-alpha (show TNF ELISA Kits)-induced production of cytokines and chemokines

  10. explored the relationship between 5-LO and central and peripheral eosinophilia in an asthma model using PAS (show PASK ELISA Kits) or BALB/c mice and 5-LO-deficient mutants

ALOX5 Antigen Profile

Antigen Summary

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ALOX5

  • arachidonate 5-lipoxygenase (alox5) antibody
  • arachidonate 5-lipoxygenase (AFUA_4G02770) antibody
  • arachidonate 5-lipoxygenase (AOR_1_1362014) antibody
  • Arachidonate 5-lipoxygenase (lox5) antibody
  • arachidonate 5-lipoxygenase (ALOX5) antibody
  • arachidonate 5-lipoxygenase (Alox5) antibody
  • arachidonate 5-lipoxygenase (LOC100341714) antibody
  • 5-LO antibody
  • 5-LOX antibody
  • 5LO antibody
  • 5LPG antibody
  • 5LX antibody
  • AI850497 antibody
  • F730011J02 antibody
  • LOG5 antibody
  • lox5 antibody
  • LOX5A antibody
  • si:dkey-194n13.2 antibody

Protein level used designations for ALOX5

LOX2 , arachidonate 5-lipoxygenase , Arachidonate 5-lipoxygenase , LOX-5 , arachidonic 5-lipoxygenase alpha-10 isoform , arachidonic 5-lipoxygenase delta-10-13 isoform , arachidonic 5-lipoxygenase delta-13 isoform , arachidonic 5-lipoxygenase delta-p10 isoform , arachidonic acid 5-lipoxygenase , leukotriene A4 synthase , 5 - Lipoxygenase , 5-LO , 5-lipoxygenase

GENE ID SPECIES
567204 Danio rerio
3503886 Aspergillus fumigatus Af293
5994193 Aspergillus oryzae RIB40
100194803 Salmo salar
240 Homo sapiens
25290 Rattus norvegicus
477753 Canis lupus familiaris
11689 Mus musculus
100341714 Oryctolagus cuniculus
100718093 Cavia porcellus
100156205 Sus scrofa
404074 Bos taurus
423769 Gallus gallus
101117390 Ovis aries
101839970 Mesocricetus auratus
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