Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
ALOX5AP encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Additionally we are shipping ALOX5AP Kits (8) and ALOX5AP Proteins (5) and many more products for this protein.
Showing 10 out of 63 products:
Human Polyclonal ALOX5AP Primary Antibody for ELISA, ICC - ABIN268657
Finkensieper, Kieser, Bekhite, Richter, Mueller, Graebner, Figulla, Sauer, Wartenberg: The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells. in Cardiovascular research 2010
Show all 3 Pubmed References
Human Polyclonal ALOX5AP Primary Antibody for IHC (p), IHC - ABIN251683
Kaaman, Rydén, Axelsson, Nordström, Sicard, Bouloumié, Langin, Arner, Dahlman: ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance. in International journal of obesity (2005) 2006
Mouse (Murine) Monoclonal ALOX5AP Primary Antibody for WB - ABIN968396
Liu, Yin: Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies. in The Journal of biological chemistry 1998
Human Polyclonal ALOX5AP Primary Antibody for IHC, IHC (p) - ABIN4312085
Perisic, Hedin, Razuvaev, Lengquist, Osterholm, Folkersen, Gillgren, Paulsson-Berne, Ponten, Odeberg, Hedin: Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis. in Arteriosclerosis, thrombosis, and vascular biology 2013
ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin (show INS Antibodies) Resistance
Data indicate that a single amino acid mutation was sufficient to reverse the speciation observed in wild type 5-Lipoxygenase activating protein (FLAP).
BRP (show GDF5 Antibodies)-7 potently suppresses leukotriene biosynthesis by interacting with FLAP in mouse peritonitis model.
FLAP regulates phosphorylation of tau protein via modulating GSK-3beta (show GSK3b Antibodies) activity.
This study demonistrated that a a novel role for FLAP in the pathogenesis of anxiety-like behavior in mice.
Deletion of myeloid cell FLAP markedly attenuates the proliferative response to vascular injury, while preserving endothelial integrity.
A FLAP inhibitor given during critical window periods may prevent oxygen induced aberration of pulmonary alveolarization in a dose- and time-dependent manner.
the 5-LO (show ALOX5 Antibodies) pathway emerges early during embryonic stem cell differentiation into cells of the myeloid lineage
Adipose tissue from obese mice, compared with that from lean mice, exhibited increased 5-LO (show ALOX5 Antibodies) activating protein
Data show that 5-lipoxygenase (show ALOX5 Antibodies) activity increases during senescence-like growth arrest via a p53 (show TP53 Antibodies)/p21 (show D4S234E Antibodies)-dependent pathway in both human and mouse embryo fibroblasts.
The results the study indicate that SNP genetic variants of ALOX5AP might play a role in the development of SSc (show CYP11A1 Antibodies)-related pulmonary fibrosis and ventilatory dysfunction.
The observation that the coexpression of FLAP with a subset of the 5-LOX (show ALOX5 Antibodies) mutants restores 5-LOX (show ALOX5 Antibodies)-wild-type (wt)-like levels of products formed in intact cells suggests a physical protein-protein interaction, beyond colocalization, of 5-LOX (show ALOX5 Antibodies) and FLAP.
Meta-analysis suggests that the A allele at the ALOX5AP SG13S114 polymorphism is a protective factor for the ischemic stroke in the European population
Genetic polymorphisms of T-1131C APOA5 (show APOA5 Antibodies) and ALOX5AP SG13S114 can be considered risk factors for the susceptibility to ischemic stroke in Morocco.
No association was found between single-nucleotide polymorphisms of ALOX5AP or PDE4D (show PDE4D Antibodies) and the risk of overall ischemic stroke in a southeastern Chinese population. The ALOX5AP gene might be related to ischemic stroke incidence in females.
Genetic interaction of CD80 (show CD80 Antibodies) and ALOX5AP was observed in systemic lupus erythematosus in Asian populations.
findings show that several enzymes known to be involved in the biosynthesis of proinflammatory LTs, such as FLAP and cPLA2alpha (show PLA2G4A Antibodies), also contribute to LX and Rv formation
The results of this study supported the association of the epistatic interactions of ALOX5AP, THBD (show THBD Antibodies), and KNG1 (show KNG1 Antibodies) and present novel evidence for the main effect of KNG1 (show KNG1 Antibodies) gene on IS susceptibility
results of the meta-analysis indicate that ALOX5AP rs10507391/SG13S114 A>T polymorphism is not associated with the risk of cerebral infarction in the Chinese population.
ALOX5AP, CPNE3 (show CPNE3 Antibodies), IL1R2 (show IL1R2 Antibodies), IL6 (show IL6 Antibodies), TLR2 (show TLR2 Antibodies), TLR4 (show TLR4 Antibodies), and THY1 (show THY1 Antibodies) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
arachidonate 5-lipoxygenase-activating protein
, Arachidonate 5-lipoxygenase-activating protein
, MK-886-binding protein
, arachidonate 5 lipoxygenase activating protein
, 5-lipoxygenase-activating protein FLAP
, arachidonate 5-lipoxygenase activating protein
, 5-lipoxygenase-activating protein