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GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.. Additionally we are shipping ACAP1 Proteins (5) and ACAP1 Kits (1) and many more products for this protein.
Showing 10 out of 63 products:
Human Polyclonal ACAP1 Primary Antibody for IP, ELISA - ABIN250037
Jackson, Brown, Nie, Miura, Foroni, Sun, Hsu, Donaldson, Randazzo: ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. in The Journal of cell biology 2000
The serum lever of Alzheimer's disease were decrease and the expression of ACAP1 strongly correlated with the Mini-Mental State Examination scores of the AD patients
ACAP1 and ARAP2 (show ARAP2 Antibodies) each colocalize with Arf6 (show ARF6 Antibodies) but they did not colocalize with each other and have opposing effects on focal adhesions.
CENTB1 was up-regulated in patients with active UC as compared to UC remission and healthy control groups suggesting that it is involved in the inflammatory process.
phosphorylation of ACAP1 relieves a localized mechanism of autoinhibition in regulating cargo binding
the oncogenic potential of USP6 (show USP6 Antibodies) is linked to its ability to integrate cell migration and cytokinesis by regulating Arf6 (show ARF6 Antibodies)/ACAP1.
ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.
CENTB1 selectively down-regulates NF-kappaB (show NFKB1 Antibodies) activation via NODs pathways, creating a "feedback" loop and suggesting a novel role of CENTB1 in innate immune responses to bacteria and inflammatory responses
Results suggest that two ARF6 (show ARF6 Antibodies) downstream molecules, PIP5K (show PIKFYVE Antibodies) and ACAP1, function together in endosomal tubulation and that phosphoinositide levels may regulate endosomal dynamics.
Results suggest that ACAP1, a GTPase-activating protein (GAP) for ADP-ribosylation factor (show ARF1 Antibodies) (ARF) 6 (show ARF6 Antibodies), is part of a novel clathrin coat complex that is regulated by ARF6 (show ARF6 Antibodies) for endocytic recycling in two key physiological settings.
ACAP1 has robust, constitutive Arf6 (show ARF6 Antibodies) GAP activity in vivo, with little activity toward Arf1 (show ARF1 Antibodies).
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.
, centaurin, beta 1
, ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
, arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1-like
, arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
, Arf GAP with coiled coil, ANK repeat and PH domains 1